Effectiveness of add-on low-dose diuretics in combination therapy for hypertension: Losartan/hydrochlorothiazide vs. candesartan/amlodipine

Hypertension Research

Volumn 30, Issue 9, 2007, Pages 831-837

  Shimosawa, Tatsuo ^a   Gohchi, Kengo ^b   Yatomi, Yutaka ^a   Fujita, Toshiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b San ikukai Hospital   (Japan)

Author keywords

Guidelines; Potassium; Uric acid

Indexed keywords

AMLODIPINE; AMLODIPINE PLUS CANDESARTAN; CANDESARTAN; CHOLESTEROL; HEMOGLOBIN A1C; HYDROCHLOROTHIAZIDE PLUS LOSARTAN; POTASSIUM; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BLOOD PRESSURE MEASUREMENT; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIASTOLIC BLOOD PRESSURE; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; FEMALE; HUMAN; HYPERTENSION; LABORATORY TEST; LOW DRUG DOSE; MALE; POTASSIUM BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC BLOOD PRESSURE; URIC ACID BLOOD LEVEL;

AGED; AMLODIPINE; ANTIHYPERTENSIVE AGENTS; ASIAN CONTINENTAL ANCESTRY GROUP; BENZIMIDAZOLES; DIURETICS; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; HYDROCHLOROTHIAZIDE; HYPERTENSION; JAPAN; LOSARTAN; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; TETRAZOLES; TREATMENT OUTCOME;

EID: 35348909647     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.30.831     Document Type: Article

References (16)

1. Chobanian AV, Bakris GL, Black HR, et al: The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003; 289: 2560-2572.
2. 2003 European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 2003; 21: 1011-1053.
3. Japanese Society of Hypertension: Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2004). Hypertens Res 2006; 29 (Suppl): S1-S105.
4. Laragh JH: Abstract, closing summary, and table of contents for Laragh's 25 lessons in pathophysiology and 12 clinical pearls for treating hypertension. Am J Hypertens 2001; 14: 1173-1177.
5. Kim-Mitsuyama S, Izumi Y, Izumiya Y, Yoshida K, Yoshiyama M, Iwao H: Additive beneficial effects of the combination of a calcium channel blocker and an angiotensin blocker on a hypertensive rat-heart failure model. Hypertens Res 2004; 27: 771-779.
6. Suzuki J, Iwai M, Li Z, et al: Effect of combination of calcium antagonist, azelnidipine, and AT1 receptor blocker, olmesartan, on atherosclerosis in apolipoprotein E-deficient mice. J Hypertens 2005; 23: 1383-1389.
7. Mancia G, Seravalle G, Grassi G: Tolerability and treatment compliance with angiotensin II receptor antagonists. Am J Hypertens 2003; 16: 1066-1073.
8. Mori H, Ukai H, Yamamoto H, et al: Current status of anti-hypertensive prescription and associated blood pressure control in Japan. Hypertens Res 2006; 29: 143-151.
9. MacKay JH, Arcuri KE, Goldberg AI, Snapinn SM, Sweet CS: Losartan and low-dose HCTZ in patients with essential hypertension. A double-blind, placebo-controlled trial of concomitant administration compared with individual components. Arch Intern Med 1996; 156: 278-285.
10. Dahlof B, Lindholm LH, Carney S, Pentikainen PJ, Ostergren J, LOA Study Group: Main results of the losartan versus amlodipine (LOA) study on drug tolerability and psychological general well-being. J Hypertens 1997; 15: 1327-1335.
11. Menard J: Critical assessment of combination therapy development. Blood Press Suppl 1993; 1: 5-9.
12. Carlsen JE, Kober L, Torp-Pedersen C, Johansen P: Relation between dose of bendrofluazide, antihypertensive effect, and adverse biochemical effects. BMJ 1990; 300: 975-978.
13. Jounela AJ, Lilja M, Lumme J, et al: Relation between low dose of HCTZ, antihypertensive effect and adverse effects. Blood Press 1994; 3: 231-235.
14. MacKenney JM, Goodman RP, Wright JT Jr, Rifai N, Aycock DG, King ME: The effect of low-dose hydrochlarothiazide on blood pressure, serum potasium, and lipoproteins. Pharmacotherapy 1986; 6: 179-184.
15. Plavinik FL, Rodrigues CI, Zanella MT, Ribeiro AB: Hypokalemia, glucose intolerance, and hyperinsulinemia during diuretic therapy. Hypertension 1992; 19 (2 Suppl): II26-II29.
16. Nakashima M, Uematsu T, Kosuge K, Kanamaru M: Pilot study of the uricosuric effect of DuP-753, a new angiotensin II receptor antagonist, in healthy subjects. Eur J Clin Pharmacol 1992; 42: 333-335.