High accumulation of calcium and phosphorus in the pineal bodies with aging

Biological Trace Element Research

Volumn 119, Issue 2, 2007, Pages 120-127

  Ongkana, Nutcharin ^a,b   Zhao, Xiao Zhen ^a,c   Tohno, Setsuko ^a   Azuma, Cho ^a   Moriwake, Yumi ^a   Minami, Takeshi ^d   Tohno, Yoshiyuki ^a  

^a NARA MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Faculty of Medicine Chiang Mai University   (Thailand)

^c FUJIAN MEDICAL UNIVERSITY   (China)

^d KINKI UNIVERSITY   (Japan)

Author keywords

Aging; Artery; Calcium; Magnesium; Phosphorus; Pineal body; Pineal gland

Indexed keywords

CALCIUM; MAGNESIUM; PHOSPHORUS;

ABDOMINAL AORTA; ADULT; AGED; AGING; ARTERY; ARTICLE; ATOMIC EMISSION SPECTROMETRY; CADAVER; COMMON CAROTID ARTERY; CORONARY ARTERY; FEMALE; HUMAN; HUMAN TISSUE; ILIAC ARTERY; MALE; PINEAL BODY; PULMONARY ARTERY; SPLEEN ARTERY; THORACIC AORTA;

AGED; AGED, 80 AND OVER; AGING; ARTERIES; CALCIUM; FEMALE; HUMANS; MAGNESIUM; MALE; MIDDLE AGED; PHOSPHORUS; PINEAL GLAND; SPECTROPHOTOMETRY, ATOMIC; SULFUR;

EID: 35348907902     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12011-007-0054-4     Document Type: Article

References (16)

1. Okudera H, Hara H, Kobayashi S et al (1986) Evaluation of the intracranial calcification associated with aging on computerized tomography. No To Shinkei 38:129-133
2. Winkler P, Helmke K (1987) Age-related incidence of pineal gland calcification in children: a roentgenological study of 1,044 skull films and a review of the literature. J Pineal Res 4:247-252
3. Kwak R, Takeuchi F, Ito S et al (1988) Intracranial physiological calcification on computed tomography (part 1): calcification of pineal region. No To Shinkei 40:569-574
4. Schmid HA, Requintina PJ, Oxenkrug GF et al (1994) Calcium, calcification, and melatonin biosynthesis in the human pineal gland: a postmortem study into age-related factors. J Pineal Res 16:178-183
5. Sandyk R (1994) The relationship of pineal calcification to cerebral atrophy on CT scan in multiple sclerosis. Int J Neurosci 76:71-79
6. Schmid HA, Raykhtsaum G (1995) Age-related differences in the structure of human pineal calcium deposits: results of transmission electron microscopy and mineralographic microanalysis. J Pineal Res 18:12-20
7. Arai Y, Yoshihara S, Iinuma K (1995) Brain CT studies in 26 cases of aged patients with Down syndrome. No To Hattatsu 27:17-22
8. Humbert W, Pevet P (1995) Calcium concretions in the pineal gland of aged rats: an ultrastructural and microanalytical study of their biogenesis. Cell Tissue Res 279:565-573
9. Humbert W, Cuisinier F, Voegel J-C et al (1997) A possible role of collagen fibrils in the process of calcification observed in the capsule of the pineal gland in aging rats. Cell Tissue Res 288:435-439
10. Swietoslawski J (1999) The age-related quantitative ultrastructural changes in pinealocytes of gerbils. Neuroendocrinol Lett 20:391-396
11. Tohno Y, Tohno S, Minami T et al (1996) Age-related changes of mineral contents in human thoracic aorta and in the cerebral artery. Biol Trace Elem Res 54:23-31
12. Pelham RW, Vaughan GM, Sandock KL et al (1973) Twenty-four hour cycle of a melatonin-like substance in the plasma of human males. J Clin Endocrinol Metab 37:341a-344a
13. Commentz JC, Fischer P, Stegner H et al (1986) Pineal calcification does not affect melatonin production. J Neural Transm Suppl 21:481-502
14. Mori R, Kodaka T, Sano T (2003) Preliminary report on the correlations among pineal concretions, prostatic calculi and age in human adult males. Anat Sci Int 78:181-184
15. Tohno Y, Tohno S, Moriwake Y et al (2001) Accumulation of calcium and phosphorus accompanied by increase of magnesium and decrease of sulfur in human arteries. Biol Trace Elem Res 82:9-19
16. Tohno S, Tohno Y, Moriwake Y et al (2001) Quantitative changes of calcium, phosphorus, and magnesium in common iliac arteries with aging. Biol Trace Elem Res 84:57-66