Preproenkephalin knockout mice show no depression-related phenotype

Neuropsychopharmacology

Volumn 32, Issue 11, 2007, Pages 2330-2337

  Bilkei Gorzo, Andras ^a   Michel, Kerstin ^a   Noble, Florence ^b   Roques, Bernard P ^b   Zimmer, Andreas ^a  

^a UNIVERSITY OF BONN   (Germany)

^b Centre National de la Recherche Scientifique   (France)

Author keywords

Animals model; Antidepressant drugs; Depression; Enkephalin; Enkephalinase inhibitor; Knockout

Indexed keywords

AMITRIPTYLINE; ANTIDEPRESSANT AGENT; FLUOXETINE; IMIPRAMINE; N [3 [(2 AMINO 4 METHYLTHIO)BUTYLDITHIO] 2 BENZYLPROPIONYL]PHENYLALANINE BENZYL ESTER; NALTRINDOLE; NIALAMIDE; PREPROENKEPHALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG EFFICACY; DRUG MECHANISM; FORCED SWIMMING TEST; GENE DELETION; GENOTYPE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; DEPRESSION; DISEASE MODELS, ANIMAL; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENKEPHALINS; ENZYME INHIBITORS; HINDLIMB SUSPENSION; IMMOBILITY RESPONSE, TONIC; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, KNOCKOUT; MOTOR ACTIVITY; NIALAMIDE; PHENOTYPE; PHENYLALANINE; PROTEIN PRECURSORS; SWIMMING; VOCALIZATION, ANIMAL;

EID: 35348887819     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1301370     Document Type: Article

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