Primary hyperaldosteronism is associated with derangement in the regulation of the hypothalamus-pituitary-adrenal axis in humans

Journal of Endocrinological Investigation

Volumn 30, Issue 7, 2007, Pages 558-563

  Giordano, R ^a   Pellegrino, M ^a   Picu, A ^a   Bonelli, L ^a   Oleandri, S E ^b   Pellissetto, C ^c   Limone, P ^c   Migliaretti, G ^d   Maccario, M ^a   Ghigo, E ^a   Arvat, Emanuela ^a  

^a Division of Endocrinology   (Italy)

^b Division of Endocrinology and Metabolism   (Italy)

^c MAURIZIANO HOSPITAL   (Italy)

^d UNIVERSITY OF TURIN   (Italy)

Author keywords

ACTH; Canrenoate; Cortisol; Humans; Hyperaldosteronism; Mineralocorticoid receptors

Indexed keywords

ALDOSTERONE; CANRENOATE POTASSIUM; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; HYDROCORTISONE; PLACEBO;

ADULT; ALDOSTERONE BLOOD LEVEL; ALDOSTERONE RELEASE; ARTICLE; BOLUS INJECTION; CLINICAL ARTICLE; CLINICAL FEATURE; CONTINUOUS INFUSION; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; CORTICOTROPIN RELEASE; DISEASE ASSOCIATION; FEMALE; FLUSHING; HORMONE RESPONSE; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; HYPERTENSION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; PRIMARY HYPERALDOSTERONISM; SIDE EFFECT; UNSPECIFIED SIDE EFFECT;

EID: 35348884312     PISSN: 03914097     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03346349     Document Type: Article

References (24)

1. Orth DN. Corticotropin-releasing hormone in humans. Endocr Rev 1992, 13: 164-91.
2. Gaillard RC, Al-Damluji S. Stress and the pituitary-adrenal axis. Baillieres Clin Endocrinol Metab 1987, 1: 319-54.
3. De Kloet ER, Vreugdenhil E, Oitzl MS, Joels M. Brain corticosteroid receptor balance in health and disease. Endocr Rev 1998, 19: 269-301.
4. Jacobson L, Sapolsky R. The role of hippocampus in feedback regulation of the hypothalamic-pituitary-adrenocortical axis. Endocr Rev 1991, 12: 118-34.
5. Funder JW. Glucocorticoid and mineralocorticoid receptors: biology and clinical relevance. Ann Rev Med 1997, 48: 231-40.
6. Draper N, Stewart PM. 11beta-hydroxysteroid dehydrogenase and the pre-receptor regulation of corticosteroid hormone action. J Endocrinol 2005, 186: 251-71.
7. Funder JW. Mineralocorticoid receptors: distribution and activation. Heart Fail Rev 2005, 10: 15-22.
8. Herman JP, Prewitt CM, Cullinan WE. Neuronal circuit regulation of the hypothalamo-pituitary-adrenocortical stress axis. Crit Rev Neurobiol 1996, 10: 371-94.
9. Herman JP, Watson SJ, Spencer RL. Defense of adrenocorticosteroid receptor expression in rat hippocampus: effects of stress and strain. Endocrinology 1999, 140: 3981-91.
10. Swanson LW. Biochemical switching in hypothalamic circuits mediating responses to stress. Prog Brain Res 1991, 87: 181-200.
11. Oittzl MS, van Haarst AD, Sutanto W, De Kloet ER. Corticosterone, brain mineralcorticoid receptors (MRs) and the activity of the hypothalamic-pituitary-adrenal (HPA) axis: the Lewis rat as an example of increased central MR capacity and a hyporesponsive HPA axis. Psychoneuroendocrinology 1995, 20: 655-75.
12. Young EA, Lopez JF, Murphy-Weinberg V, Watson SJ, Akil H. The role of mineralocorticoid receptors in hypothalamic-pituitary-adrenal axis regulation in humans. J Clin Endocrinol Metab 1998, 83: 3339-45.
13. Dodt C, Kern W, Fehm HL, Born J. Antimineralocorticoid canrenoate enhances secretory activity of the hypothalamus-pituitary-adrenocortical (HPA) axis in humans. Neuroendocrinology 1993, 58: 570-4.
14. Deuschle M, Weber B, Colla M, Muller M, Kniest A, Heuser I. Mineralocorticoid receptor also modulates basal activity of hypothalamus-pituitary-adrenocortical system in humans. Neuroendocrinology 1998, 68: 355-60.
15. Arvat E, Maccagno B, Giordano R, et al. Mineralocorticoid receptor blockade by canrenoate increases both spontaneous and stimulated adrenal function in humans. J Clin Endocrinol Metab 2001, 86: 3176-81.
16. Wiedemann K, Lauer C, Pollmacher T, Holsboer F. Sleep endocrine effects of antigluco- and antimineralocorticoids in healthy males. Am J Physiol 1994, 267: E109-14.
17. Kalman BA, Spencer RL. Rapid corticosteroid-dependent regulation of mineralocorticoid receptor protein expression in rat brain. Endocrinology 2002, 143: 4184-95.
18. Young EA, Lopez JF, Murphy-Weinberg V, Watson SJ, Akil H. Mineralocorticoid receptor function in major depression. Arch Gen Psychiatry 2003, 60: 24-8,
19. Mancini T, Kola B, Mantero F, Arnalcli G. Functional and nonfunctional adrenocortical tumors demonstrate a high responsiveness to low-dose adrenocorticotropin. J Clin Endocrinol Metab 2003, 88: 1994-8.
20. Schubert B, Fassnacht M, Beuschlein F, Zenkert S, Allolio B, Reincke M. Angiotensin II type 1 receptor and ACTH receptor expression in human adrenocortical neoplasms. Clin Endocrinol (Oxf) 2001, 54: 627-32.
21. Arnaldi G, Mancini V, Costantini C, et al. ACTH receptor mRNA in human adrenocortical tumors: overexpression in aldosteronomas. Endocr Res 1998, 24: 845-9.
22. Orth DN, Kovacs WJ. The adrenal cortex. In: Wilson JD, Foster DW eds., Williams textbook of endocrinology, Philadelphia: WB Saunders. 1992, 534-44.
23. Kater CE, Biglieri EG, Brust N, Chang B, Hirai J, Irony I. Stimulation and suppression of the mineralocorticoid hormones in normal subjects and adrenocortical disorders. Endocr Rev 1989, 10: 149-64.
24. Arvat E, Di Vito L, Lanfranco F, et al. Stimulatory effect of adrenocorticotropin on cortisol, aldosterone, and dehydroepiandrosterone secretion in normal humans: dose-response study. J Clin Endocrinol Metab 2000, 85: 3141-6.