The possible influence of LuxS in the in vivo virulence of rabbit enteropathogenic Escherichia coli

Veterinary Microbiology

Volumn 125, Issue 3-4, 2007, Pages 313-322

  Zhu, Chengru ^a,b   Feng, Shuzhang ^a   Sperandio, Venessa ^c   Yang, Zhuolu ^a   Thate, Timothy E ^a   Kaper, James B ^a   Boedeker, Edgar C ^b  

^a University of Maryland School of Medicine Center for Vaccine Development   (United States)

^b UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Autoinducer; LEE; Quorum sensing; Regulation

Indexed keywords

S RIBOSYLHOMOCYSTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BIOLUMINESCENCE; CONTROLLED STUDY; DNA STRUCTURE; ENTEROPATHOGENIC ESCHERICHIA COLI; HUMAN; HUMAN CELL; INTESTINE MUCOSA; LEE ISLAND; LUXS GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PLASMID; PROTEIN EXPRESSION; QUORUM SENSING; RABBIT;

ANIMALS; BACTERIAL ADHESION; BACTERIAL PROTEINS; CARBON-SULFUR LYASES; DNA, BACTERIAL; ENTEROPATHOGENIC ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FECES; HELA CELLS; HOMOSERINE; HUMANS; INTESTINAL DISEASES; INTESTINAL MUCOSA; LACTONES; MALE; MUTAGENESIS, INSERTIONAL; QUORUM SENSING; RABBITS; VIRULENCE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; ORYCTOLAGUS CUNICULUS;

EID: 35348824849     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetmic.2007.05.030     Document Type: Article

References (35)

1. Agin T.S., Zhu C., Johnson L.A., Thate T.E., Yang Z., and Boedeker E.C. Protection against hemorrhagic colitis in an animal model by oral immunization with isogeneic rabbit enteropathogenic Escherichia coli attenuated by truncating intimin. Infect. Immun. 73 (2005) 6608-6619
2. Bloom P.D., and Boedeker E.C. Mucosal immune responses to intestinal bacterial pathogens. Semin. Gastrointest. Dis. 7 (1996) 151-166
3. Clarke M.B., Hughes D.T., Zhu C., Boedeker E.C., and Sperandio V. The QseC sensor kinase: a bacterial adrenergic receptor. Proc. Natl. Acad. Sci. USA 103 (2006) 10420-10425
4. Day Jr. W.A., and Maurelli A.T. Shigella flexneri LuxS quorum-sensing system modulates virB expression but is not essential for virulence. Infect. Immun. 69 (2001) 15-23
5. DeLisa M.P., Valdes J.J., and Bentley W.E. Mapping stress-induced changes in autoinducer AI-2 production in chemostat-cultivated Escherichia coli K-12. J. Bacteriol. 183 (2001) 2918-2928
6. Deng W., Li Y., Vallance B.A., and Finlay B.B. Locus of enterocyte effacement from Citrobacter rodentium: sequence analysis and evidence for horizontal transfer among attaching and effacing pathogens. Infect. Immun. 69 (2001) 6323-6335
7. Donnenberg M.S., and Kaper J.B. Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector. Infect. Immun. 59 (1991) 4310-4317
8. Elliott S.J., Wainwright L.A., McDaniel T.K., Jarvis K.G., Deng Y.K., Lai L.C., McNamara B.P., Donnenberg M.S., and Kaper J.B. The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69. Mol. Microbiol. 28 (1998) 1-4
9. Gonzalez, Barrios A.F., Zuo R., Hashimoto Y., Yang L., Bentley W.E., and Wood T.K. Autoinducer 2 controls biofilm formation in Escherichia coli through a novel motility quorum-sensing regulator (MqsR, B3022). J. Bacteriol. 188 (2006) 305-316
10. Hilgers M.T., and Ludwig M.L. Crystal structure of the quorum-sensing protein LuxS reveals a catalytic metal site. Proc. Natl. Acad. Sci. USA 98 (2001) 11169-11174
11. Jordan D.M., Sperandio V., Kaper J.B., Dean-Nystrom E.A., and Moon H.W. Colonization of gnotobiotic piglets by a luxS mutant strain of Escherichia coli O157:H7. Infect. Immun. 73 (2005) 1214-1216
12. Joyce E.A., Bassler B.L., and Wright A. Evidence for a signaling system in Helicobacter pylori: detection of a luxS-encoded autoinducer. J. Bacteriol. 182 (2000) 3638-3643
13. Kaper J.B., and Sperandio V. Bacterial cell-to-cell signaling in the gastrointestinal tract. Infect. Immun. 73 (2005) 3197-3209
14. Keller L., and Surette M.G. Communication in bacteria: an ecological and evolutionary perspective. Nat. Rev. Microbiol. 4 (2006) 249-258
15. Marches O., Nougayrede J.P., Boullier S., Mainil J., Charlier G., Raymond I., Pohl P., Boury M., De Rycke J., Milon A., and Oswald E. Role of Tir and Intimin in the virulence of rabbit enteropathogenic Escherichia coli serotype O103:H2. Infect. Immun. 68 (2000) 2171-2182
16. McDaniel T.K., Jarvis K.G., Donnenberg M.S., and Kaper J.B. A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens. Proc. Natl. Acad. Sci. USA 92 (1995) 1664-1668
17. McDougald D., Rice S.A., and Kjelleberg S. Bacterial quorum sensing and interference by naturally occurring biomimics. Anal. Bioanal. Chem. 387 (2007) 445-453
18. Mellies J.L., Elliott S.J., Sperandio V., Donnenberg M.S., and Kaper J.B. The Per regulon of enteropathogenic Escherichia coli: identification of a regulatory cascade and a novel transcriptional activator, the locus of enterocyte effacement (LEE)-encoded regulator (Ler). Mol. Microbiol. 33 (1999) 296-306
19. Miller M.B., and Bassler B.L. Quorum sensing in bacteria. Annu. Rev. Microbiol. 55 (2001) 165-199
20. Nataro J.P., and Kaper J.B. Diarrheagenic Escherichia coli. Clin. Microbiol. Rev. 11 (1998) 142-201
21. Perna N.T., Mayhew G.F., Posfai G., Elliott S.J., Donnenberg M.S., Kaper J.B., and Blattner F.R. Molecular evolution of a pathogenicity island from enterohemorrhagic Escherichia coli O157:H7. Infect. Immun. 66 (1998) 3810-3817
22. Schauder S., Shokat K., Surette M.G., and Bassler B.L. The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule. Mol. Microbiol. 41 (2001) 463-476
23. Sircili M.P., Walters M., Trabulsi L.R., and Sperandio V. Modulation of enteropathogenic Escherichia coli virulence by quorum sensing. Infect. Immun. 72 (2004) 2329-2337
24. Sperandio V., Mellies J.L., Nguyen N., Shin S., and Kaper J.B. Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli. Proc. Natl. Acad. Sci. USA 96 (1999) 15196-15201
25. Sperandio V., Mellies J.L., Delahay R.M., Frankel G., Crawford J.A., Nguyen W., and Kaper J.B. Activation of enteropathogenic Escherichia coli (EPEC) LEE2 and LEE3 operons by Ler. Mol. Microbiol. 38 (2000) 781-793
26. Sperandio V., Torres A.G., Giron J.A., and Kaper J.B. Quorum sensing is a global regulatory mechanism in enterohemorrhagic Escherichia coli O157:H7. J. Bacteriol. 183 (2001) 5187-5197
27. Sperandio V., Torres A.G., Jarvis B., Nataro J.P., and Kaper J.B. Bacteria-host communication: the language of hormones. Proc. Natl. Acad. Sci. USA 100 (2003) 8951-8956
28. Surette M.G., and Bassler B.L. Quorum sensing in Escherichia coli and Salmonella typhimurium. Proc. Natl. Acad. Sci. USA 95 (1998) 7046-7050
29. Torres A.G., Giron J.A., Perna N.T., Burland V., Blattner F.R., Avelino-Flores F., and Kaper J.B. Identification and characterization of lpfABCC'DE, a fimbrial operon of enterohemorrhagic Escherichia coli O157:H7. Infect. Immun. 70 (2002) 5416-5427
30. Vendeville A., Winzer K., Heurlier K., Tang C.M., and Hardie K.R. Making 'sense' of metabolism: autoinducer-2 LuxS and pathogenic bacteria. Nat. Rev. Microbiol. 3 (2005) 383-396
31. Walters M.M.P., Sircili M.P., and Sperandio V. AI-3 synthesis is not dependent on luxS in Escherichia coli. J. Bacteriol. 188 (2006) 5668-5681
32. Walters M., and Sperandio V. Autoinducer 3 and epinephrine signaling in the kinetics of locus of enterocyte effacement gene expression in enterohemorrhagic Escherichia coli. Infect. Immun. 74 (2006) 5445-5455
33. Xavier K.B., and Bassler B.L. Interference with AI-2-mediated bacterial cell-cell communication. Nature 437 (2005) 750-753
34. Zhu C., Agin T.S., Elliott S.J., Johnson L.A., Thate T.E., Kaper J.B., and Boedeker E.C. Complete nucleotide sequence and analysis of the locus of enterocyte effacement from rabbit diarrheagenic Escherichia coli RDEC-1. Infect. Immun. 69 (2001) 2107-2115
35. Zhu C., Feng S., Thate T.E., Kaper J.B., and Boedeker E.C. Towards a vaccine for attaching/effacing Escherichia coli: a LEE-encoded regulator (ler) mutant of rabbit enteropathogenic Escherichia coli is attenuated, immunogenic, and protects rabbits from lethal challenge with the wild-type virulent strain. Vaccine 24 (2006) 3845-3855