Progesterone receptor or cytoskeletal protein?

Reproductive Sciences

Volumn 14, Issue 3, 2007, Pages 217-222

  Madsen, Gemma ^a,c   MacIntyre, David A ^a   Mesiano, Sam ^b   Smith, Roger ^a  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JOHN HUNTER HOSPITAL   (Australia)

Author keywords

Cytoskeletal proteins; Immunoblotting; Progesterone receptor

Indexed keywords

ALPHA ACTININ; CYTOSKELETON PROTEIN; DESMIN; PROGESTERONE RECEPTOR ANTIBODY; RECEPTOR ANTIBODY; UNCLASSIFIED DRUG; VIMENTIN; ACTIN; ANTIBODY; DIAGNOSTIC AGENT; PROGESTERONE RECEPTOR; SC 538 ANTIBODY, HUMAN; SC-538 ANTIBODY, HUMAN;

ARTICLE; CELL LINE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MYOMETRIUM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; ADULT; ANTIBODY SPECIFICITY; CHEMISTRY; FEMALE; IMMUNOLOGY; IMMUNOPRECIPITATION; ISOLATION AND PURIFICATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PREGNANCY; SEQUENCE ANALYSIS;

ACTINS; ADULT; ANTIBODIES; ANTIBODY SPECIFICITY; CELL LINE; CHROMATOGRAPHY, LIQUID; CYTOSKELETAL PROTEINS; DESMIN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MYOMETRIUM; PREGNANCY; RECEPTORS, PROGESTERONE; SEQUENCE ANALYSIS, PROTEIN; VIMENTIN;

EID: 35348820761     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719107302380     Document Type: Article

References (24)

1. Conneely OM, Lydon JP, De Mayo F., O'Malley BW Reproductive functions of the progesterone receptor. J Soc Gynecol Investig. 2000 ; 7 (1 suppl). S25 - S32.
2. Leonhardt SA, Edwards DP Mechanism of action of progesterone antagonists. Exp Biol Med (Maywood). 2002 ; 227: 969-980.
3. Kastner P., Krust A., Turcotte B., et al. Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J. 1990 ; 9: 1603-1614.
4. Giangrande PH, McDonnell DP The A and B isoforms of the human progesterone receptor: two functionally different transcription factors encoded by a single gene. Recent Prog Horm Res. 1999 ; 54: 291-313.
5. Giangrande PH, Kimbrel EA, Edwards DP, McDonnell DP The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding. Mol Cell Biol. 2000 ; 20: 3102-3115.
6. Vegeto E., Shahbaz MM, Wen DX, Goldman ME, O'Malley BW, McDonnell DP. Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. Mol Endocrinol. 1993 ; 7: 1244-1255.
7. Tung L., Mohamed MK, Hoeffler JP, Takimoto GS, Horwitz KB Antagonist-occupied human progesterone B-receptors activate transcription without binding to progesterone response elements and are dominantly inhibited by A-receptors. Mol Endocrinol. 1993 ; 7: 1256-1265.
8. Condon JC, Hardy DB, Kovaric K., Mendelson CR Up-regulation of the progesterone receptor (PR)-C isoform in laboring myometrium by activation of nuclear factor-kappaB may contribute to the onset of labor through inhibition of PR function. Mol Endocrinol. 2006 ; 20: 764-775.
9. Taylor AH, McParland PC, Taylor DJ, Bell SC The progesterone receptor in human term amniochorion and placenta is isoform C. Endocrinology. 2006 ; 147: 687-693.
10. Wei LL, Hawkins P., Baker C., Norris B., Sheridan PL, Quinn PG An amino-terminal truncated progesterone receptor isoform, PRc, enhances progestin-induced transcriptional activity. Mol Endocrinol. 1996 ; 10: 1379-1387.
11. Welter BH, Hansen EL, Saner KJ, Wei Y., Price TM Membrane-bound progesterone receptor expression in human aortic endothelial cells. J Histochem Cytochem. 2003 ; 51: 1049-1055.
12. O'Brien SN, Welter BH, Mantzke KA, Price TM Identification of progesterone receptor in human subcutaneous adipose tissue. J Clin Endocrinol Metab. 1998 ; 83: 509-513.
13. Mesiano S., Chan EC, Fitter JT, Kwek K., Yeo G., Smith R. Progesterone withdrawal and estrogen activation in human parturition are coordinated by progesterone receptor A expression in the myometrium. J Clin Endocrinol Metab. 2002 ; 87: 2924-2930.
14. Madsen G., Zakar T., Ku CY, Sanborn BM, Smith R., Mesiano S. Prostaglandins differentially modulate progesterone receptor-A and -B expression in human myometrial cells: evidence for prostaglandin-induced functional progesterone withdrawl. J Clin Endocrinol Metab. 2004 ; 89: 1010-1013.
15. Scheer JM, Ryan CA A method for the quantitative recovery of proteins from polyacrylamide gels. Anal Biochem. 2001 ; 298: 130-132.
16. Osborn M., Debus E., Weber K. Monoclonal antibodies specific for vimentin. Eur J Cell Biol. 1984 ; 34: 137-143.
17. Pollock L., Rampling D., Greenwald SE, Malone M. Desmin expression in rhabdomyosarcoma: influence of the desmin clone and immunohistochemical method. J Clin Pathol. 1995 ; 48: 535-538.
18. Feramisco JR, Blose SH Distribution of fluorescently labeled alpha-actinin in living and fixed fibroblasts. J Cell Biol. 1980 ; 86: 608-615.
19. Brown AG, Leite RS, Strauss JF III. Mechanisms underlying "functional" progesterone withdrawal at parturition. Ann N Y Acad Sci. 2004 ; 1034: 36-49.
20. Mesiano S. Myometrial progesterone responsiveness and the control of human parturition. J Soc Gynecol Investig. 2004 ; 11: 193-202.
21. Pieber D., Allport VC, Hills F., Johnson M., Bennett PR Interactions between progesterone receptor isoforms in myometrial cells in human labour. Mol Hum Reprod. 2001 ; 7: 875-879.
22. Merlino AA, Welsh TN, Tan H., et al. Nuclear progesterone receptors in the human pregnancy myometrium: evidence that parturition involves functional progesterone withdrawal mediated by increased expression of PR-A. J Clin Endocrinol Metab. Epub ahead of print March 6, 2007.
23. Yu JT, Lopez Bernal A. The cytoskeleton of human myometrial cells. J Reprod Fertil. 1998 ; 112: 185-198.
24. Wilkins MR, Lindskog I., Gasteiger E., et al. Detailed peptide characterization using PEPTIDEMASS-a World-Wide-Web- accessible tool. Electrophoresis. 1997 ; 18: 403-408.