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Volumn 103, Issue 3, 2007, Pages 962-971

The neuroprotective effect of Activin A and B: Implication for neurodegenerative diseases

Author keywords

Activin; Bcl 2 family; Neurodegenerative diseases; Neuronal apoptosis; Neuroprotection

Indexed keywords

ACTIVIN A; CASPASE 3; LINSIDOMINE; MYELOPID; NEUROTOXIN; OXIDOPAMINE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BCL 2; TYROSINE 3 MONOOXYGENASE;

EID: 35248897112     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2007.04785.x     Document Type: Article
Times cited : (31)

References (46)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams J. M. Cory S. (1998) The Bcl-2 protein family: arbiters of cell survival. Science 281, 1322 1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 2
    • 0036272812 scopus 로고    scopus 로고
    • Preconditioning-mediated neuroprotection: Role of nitric oxide, cGMP, and new protein expression
    • Andoh T., Chock P. B. Chiueh C. C. (2002) Preconditioning-mediated neuroprotection: role of nitric oxide, cGMP, and new protein expression. Ann. N Y Acad Sci. 962, 1 7.
    • (2002) Ann. N Y Acad Sci. , vol.962 , pp. 1-7
    • Andoh, T.1    Chock, P.B.2    Chiueh, C.C.3
  • 3
    • 0029940901 scopus 로고    scopus 로고
    • Removal of serum from primary cultures of cerebellar granule neurons induces oxidative stress and DNA fragmentation: Protection with antioxidants and glutamate receptor antagonists
    • Atabay C., Cagnoli C. M., Kharlamov E., Ikonomovic M. D. Manev H. (1996) Removal of serum from primary cultures of cerebellar granule neurons induces oxidative stress and DNA fragmentation: protection with antioxidants and glutamate receptor antagonists. J. Neurosci. Res. 43, 465 475.
    • (1996) J. Neurosci. Res. , vol.43 , pp. 465-475
    • Atabay, C.1    Cagnoli, C.M.2    Kharlamov, E.3    Ikonomovic, M.D.4    Manev, H.5
  • 4
    • 33845879870 scopus 로고    scopus 로고
    • Therapeutic targets and potential of the novel brain- permeable multifunctional iron chelator-monoamine oxidase inhbitor drug, M-30, for the treatment of Alzheimer's disease
    • Avramovich-Tirosh Y., Amit T., Bar-Am O., Zheng H., Fridkin M. Youdim M. B. (2007) Therapeutic targets and potential of the novel brain- permeable multifunctional iron chelator-monoamine oxidase inhbitor drug, M-30, for the treatment of Alzheimer's disease. J. Neurochem. 100, 490 502.
    • (2007) J. Neurochem. , vol.100 , pp. 490-502
    • Avramovich-Tirosh, Y.1    Amit, T.2    Bar-Am, O.3    Zheng, H.4    Fridkin, M.5    Youdim, M.B.6
  • 5
    • 0037441753 scopus 로고    scopus 로고
    • The establishment of a reliable cytotoxic system with SK-N-SH neuroblastoma cell culture
    • Ba F., Pang P. K. Benishin C. G. (2003) The establishment of a reliable cytotoxic system with SK-N-SH neuroblastoma cell culture. J. Neurosci. Methods 123, 11 22.
    • (2003) J. Neurosci. Methods , vol.123 , pp. 11-22
    • Ba, F.1    Pang, P.K.2    Benishin, C.G.3
  • 6
    • 15844405843 scopus 로고    scopus 로고
    • Synergistic activity of activin a and basic fibroblast growth factor on tyrosine hydroxylase expression through Smad3 and ERK1/ERK2 MAPK signaling pathways
    • Bao Y. L., Tsuchida K., Liu B., Kurisaki A., Matsuzaki T. Sugino H. (2005) Synergistic activity of activin A and basic fibroblast growth factor on tyrosine hydroxylase expression through Smad3 and ERK1/ERK2 MAPK signaling pathways. J. Endocrinol. 184, 493 504.
    • (2005) J. Endocrinol. , vol.184 , pp. 493-504
    • Bao, Y.L.1    Tsuchida, K.2    Liu, B.3    Kurisaki, A.4    Matsuzaki, T.5    Sugino, H.6
  • 7
    • 27744486071 scopus 로고    scopus 로고
    • Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine
    • Bar-Am O., Weinreb O., Amit T. Youdim M. B. (2005) Regulation of Bcl-2 family proteins, neurotrophic factors, and APP processing in the neurorescue activity of propargylamine. FASEB J. 19, 1899 1901.
    • (2005) FASEB J. , vol.19 , pp. 1899-1901
    • Bar-Am, O.1    Weinreb, O.2    Amit, T.3    Youdim, M.B.4
  • 8
    • 0028049119 scopus 로고
    • Hybridization histochemical localization of activin receptor subtypes in rat brain, pituitary, ovary, and testis
    • Cameron V. A., Nishimura E., Mathews L. S., Lewis K. A., Sawchenko P. E. Vale W. W. (1994) Hybridization histochemical localization of activin receptor subtypes in rat brain, pituitary, ovary, and testis. Endocrinology 134, 799 808.
    • (1994) Endocrinology , vol.134 , pp. 799-808
    • Cameron, V.A.1    Nishimura, E.2    Mathews, L.S.3    Lewis, K.A.4    Sawchenko, P.E.5    Vale, W.W.6
  • 9
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • Cory S. Adams J. M. (2002) The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer 2, 647 656.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 10
    • 0036020543 scopus 로고    scopus 로고
    • Modulating poly (ADP-ribose) polymerase activity: Potential for the prevention and therapy of pathogenic situations involving DNA damage and oxidative stress
    • Decker P. Muller S. (2002) Modulating poly (ADP-ribose) polymerase activity: potential for the prevention and therapy of pathogenic situations involving DNA damage and oxidative stress. Curr. Pharm. Biotechnol. 3, 275 283.
    • (2002) Curr. Pharm. Biotechnol. , vol.3 , pp. 275-283
    • Decker, P.1    Muller, S.2
  • 11
    • 19044383923 scopus 로고    scopus 로고
    • Regulation of activin mRNA and Smad2 phosphorylation by antidepressant treatment in the rat brain: Effects in behavioral models
    • Dow A. L., Russell D. S. Duman R. S. (2005) Regulation of activin mRNA and Smad2 phosphorylation by antidepressant treatment in the rat brain: effects in behavioral models. J. Neurosci. 25, 4908 4916.
    • (2005) J. Neurosci. , vol.25 , pp. 4908-4916
    • Dow, A.L.1    Russell, D.S.2    Duman, R.S.3
  • 12
    • 0032575705 scopus 로고    scopus 로고
    • A matter of life and cell death
    • Evan G. Littlewood T. (1998) A matter of life and cell death. Science 281, 1317 1322.
    • (1998) Science , vol.281 , pp. 1317-1322
    • Evan, G.1    Littlewood, T.2
  • 13
    • 0027982943 scopus 로고
    • Neuropoietic cytokines and activin a differentially regulate the phenotype of cultured sympathetic neurons
    • Fann M. J. Patterson P. H. (1994) Neuropoietic cytokines and activin A differentially regulate the phenotype of cultured sympathetic neurons. Proc. Natl Acad. Sci. USA 91, 43 47.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 43-47
    • Fann, M.J.1    Patterson, P.H.2
  • 14
    • 3042818137 scopus 로고    scopus 로고
    • Activin mRNA induced during amygdala kindling shows a spatiotemporal progression that tracks the spread of seizures
    • Foster J. A., Puchowicz M. J., McIntyre D. C. Herkenham M. (2004) Activin mRNA induced during amygdala kindling shows a spatiotemporal progression that tracks the spread of seizures. J. Comp. Neurol. 476, 91 102.
    • (2004) J. Comp. Neurol. , vol.476 , pp. 91-102
    • Foster, J.A.1    Puchowicz, M.J.2    McIntyre, D.C.3    Herkenham, M.4
  • 15
    • 0037146556 scopus 로고    scopus 로고
    • TGF-beta1 increases tyrosine hydroxylase expression by a mechanism blocked by BMP-2 in human neuroblastoma SH-SY5Y cells
    • Gomez-Santos C., Ambrosio S., Ventura F., Ferrer I. Reiriz J. (2002) TGF-beta1 increases tyrosine hydroxylase expression by a mechanism blocked by BMP-2 in human neuroblastoma SH-SY5Y cells. Brain Res. 958, 152 160.
    • (2002) Brain Res. , vol.958 , pp. 152-160
    • Gomez-Santos, C.1    Ambrosio, S.2    Ventura, F.3    Ferrer, I.4    Reiriz, J.5
  • 16
    • 0033041786 scopus 로고    scopus 로고
    • Administration of recombinant human Activin-A has powerful neurotrophic effects on select striatal phenotypes in the quinolinic acid lesion model of Huntington's disease
    • Hughes P. E., Alexi T., Williams C. E., Clark R. G. Gluckman P. D. (1999) Administration of recombinant human Activin-A has powerful neurotrophic effects on select striatal phenotypes in the quinolinic acid lesion model of Huntington's disease. Neuroscience 92, 197 209.
    • (1999) Neuroscience , vol.92 , pp. 197-209
    • Hughes, P.E.1    Alexi, T.2    Williams, C.E.3    Clark, R.G.4    Gluckman, P.D.5
  • 17
    • 0030833665 scopus 로고    scopus 로고
    • Activin exerts a neurotrophic effect on cultured hippocampal neurons
    • Iwahori Y., Saito H., Torii K. Nishiyama N. (1997) Activin exerts a neurotrophic effect on cultured hippocampal neurons. Brain Res. 760, 52 58.
    • (1997) Brain Res. , vol.760 , pp. 52-58
    • Iwahori, Y.1    Saito, H.2    Torii, K.3    Nishiyama, N.4
  • 18
    • 0033955608 scopus 로고    scopus 로고
    • Cell death mechanisms in Parkinson's disease
    • Jellinger K. A. (2000) Cell death mechanisms in Parkinson's disease. J. Neural Transm. 107, 1 29.
    • (2000) J. Neural Transm. , vol.107 , pp. 1-29
    • Jellinger, K.A.1
  • 19
    • 0028986656 scopus 로고
    • TGF-beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP+ toxicity
    • Krieglstein K., Suter-Crazzolara C., Fischer W. H. Unsicker K. (1995) TGF-beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP+ toxicity. EMBO J. 14, 736 742.
    • (1995) EMBO J. , vol.14 , pp. 736-742
    • Krieglstein, K.1    Suter-Crazzolara, C.2    Fischer, W.H.3    Unsicker, K.4
  • 20
    • 0030038423 scopus 로고    scopus 로고
    • Sequential patterns of inhibin subunit gene expression following hypoxic-ischemic injury in the rat brain
    • Lai M., Sirimanne E., Williams C. E. Gluckman P. D. (1996) Sequential patterns of inhibin subunit gene expression following hypoxic-ischemic injury in the rat brain. Neuroscience 70, 1013 1024.
    • (1996) Neuroscience , vol.70 , pp. 1013-1024
    • Lai, M.1    Sirimanne, E.2    Williams, C.E.3    Gluckman, P.D.4
  • 21
    • 0037163110 scopus 로고    scopus 로고
    • Involvement of protein kinase C activation and cell survival/cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action
    • Levites Y., Amit T., Youdim M. B. Mandel S. (2002) Involvement of protein kinase C activation and cell survival/cell cycle genes in green tea polyphenol (-)-epigallocatechin 3-gallate neuroprotective action. J. Biol. Chem. 277, 30574 30580.
    • (2002) J. Biol. Chem. , vol.277 , pp. 30574-30580
    • Levites, Y.1    Amit, T.2    Youdim, M.B.3    Mandel, S.4
  • 23
    • 0036206323 scopus 로고    scopus 로고
    • The anti-Parkinson drug, rasagiline, prevents apoptotic DNA damage induced by peroxynitrite in human dopaminergic neuroblastoma SH-SY5Y cells
    • Maruyama W., Takahashi T., Youdim M. Naoi M. (2002) The anti-Parkinson drug, rasagiline, prevents apoptotic DNA damage induced by peroxynitrite in human dopaminergic neuroblastoma SH-SY5Y cells. J. Neural Transm. 109, 467 481.
    • (2002) J. Neural Transm. , vol.109 , pp. 467-481
    • Maruyama, W.1    Takahashi, T.2    Youdim, M.3    Naoi, M.4
  • 24
    • 0038647411 scopus 로고    scopus 로고
    • Increased activin levels in cerebrospinal fluid of rabbits with bacterial meningitis are associated with activation of microglia
    • Michel U., Gerber J., E O'Connor A., Bunkowski S., Bruck W., Nau R. Phillips D. J. (2003) Increased activin levels in cerebrospinal fluid of rabbits with bacterial meningitis are associated with activation of microglia. J. Neurochem. 86, 238 245.
    • (2003) J. Neurochem. , vol.86 , pp. 238-245
    • Michel, U.1    Gerber, J.2    O'Connor A, E.3    Bunkowski, S.4    Bruck, W.5    Nau, R.6    Phillips, D.J.7
  • 25
    • 34249320190 scopus 로고    scopus 로고
    • Activin is a neuronal survival factor that is rapidly increased after transient cerebral ischemia and hypoxia in mice
    • in press.
    • Mukerji S. S., Katsman E. A., Wilber C., Haner N. A., Selman W. R. Hall A. K. (2006) Activin is a neuronal survival factor that is rapidly increased after transient cerebral ischemia and hypoxia in mice. J. Cereb. Blood Flow Metab. in press.
    • (2006) J. Cereb. Blood Flow Metab.
    • Mukerji, S.S.1    Katsman, E.A.2    Wilber, C.3    Haner, N.A.4    Selman, W.R.5    Hall, A.K.6
  • 26
    • 33749378617 scopus 로고    scopus 로고
    • Transgenic mice expressing dominant-negative activin receptor IB in forebrain neurons reveal novel functions of activin at glutamatergic synapses
    • Muller M. R., Zheng F., Werner S. Alzheimer C. (2006) Transgenic mice expressing dominant-negative activin receptor IB in forebrain neurons reveal novel functions of activin at glutamatergic synapses. J. Biol. Chem. 281, 29076 29084.
    • (2006) J. Biol. Chem. , vol.281 , pp. 29076-29084
    • Muller, M.R.1    Zheng, F.2    Werner, S.3    Alzheimer, C.4
  • 28
    • 9044252959 scopus 로고
    • Tyrosine hydroxylase. the initial step in norepinephrine biosynthesis
    • Nagatsu T., Levitt M. Udenfriend S. (1964) Tyrosine hydroxylase. The initial step in norepinephrine biosynthesis. J. Biol. Chem. 239, 2910 2917.
    • (1964) J. Biol. Chem. , vol.239 , pp. 2910-2917
    • Nagatsu, T.1    Levitt, M.2    Udenfriend, S.3
  • 29
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai Z. N., Milliman C. L. Korsmeyer S. J. (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609 619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 31
    • 0343280013 scopus 로고    scopus 로고
    • A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
    • Paull T. T., Rogakou E. P., Yamazaki V., Kirchgessner C. U., Gellert M. Bonner W. M. (2000) A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage. Curr. Biol. 10, 886 895.
    • (2000) Curr. Biol. , vol.10 , pp. 886-895
    • Paull, T.T.1    Rogakou, E.P.2    Yamazaki, V.3    Kirchgessner, C.U.4    Gellert, M.5    Bonner, W.M.6
  • 32
    • 0028575840 scopus 로고
    • Regulation of neuronal Bcl2 protein expression and calcium homeostasis by transforming growth factor type beta confers wide-ranging protection on rat hippocampal neurons
    • Prehn J. H., Bindokas V. P., Marcuccilli C. J., Krajewski S., Reed J. C. Miller R. J. (1994) Regulation of neuronal Bcl2 protein expression and calcium homeostasis by transforming growth factor type beta confers wide-ranging protection on rat hippocampal neurons. Proc. Natl Acad. Sci. USA 91, 12599 12603.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 12599-12603
    • Prehn, J.H.1    Bindokas, V.P.2    Marcuccilli, C.J.3    Krajewski, S.4    Reed, J.C.5    Miller, R.J.6
  • 33
    • 0028156743 scopus 로고
    • Expression of messenger ribonucleic acids encoding the inhibin/activin system during mid- and late-gestation rat embryogenesis
    • Roberts V. J. Barth S. L. (1994) Expression of messenger ribonucleic acids encoding the inhibin/activin system during mid- and late-gestation rat embryogenesis. Endocrinology 134, 914 923.
    • (1994) Endocrinology , vol.134 , pp. 914-923
    • Roberts, V.J.1    Barth, S.L.2
  • 36
    • 4644356541 scopus 로고    scopus 로고
    • Activin: An important regulator of wound repair, fibrosis, and neuroprotection
    • Sulyok S., Wankell M., Alzheimer C. Werner S. (2004) Activin: an important regulator of wound repair, fibrosis, and neuroprotection. Mol. Cell. Endocrinol. 225, 127 132.
    • (2004) Mol. Cell. Endocrinol. , vol.225 , pp. 127-132
    • Sulyok, S.1    Wankell, M.2    Alzheimer, C.3    Werner, S.4
  • 38
    • 0033927181 scopus 로고    scopus 로고
    • Induction of activin a is essential for the neuroprotective action of basic fibroblast growth factor in vivo
    • Tretter Y. P., Hertel M., Munz B., ten Bruggencate G., Werner S. Alzheimer C. (2000) Induction of activin A is essential for the neuroprotective action of basic fibroblast growth factor in vivo. Nat. Med. 6, 812 815.
    • (2000) Nat. Med. , vol.6 , pp. 812-815
    • Tretter, Y.P.1    Hertel, M.2    Munz, B.3    Ten Bruggencate, G.4    Werner, S.5    Alzheimer, C.6
  • 39
    • 0037791893 scopus 로고    scopus 로고
    • The roles of activin in cytoprotection and tissue repair
    • Wankell M., Werner S. Alzheimer C. (2003) The roles of activin in cytoprotection and tissue repair. Ann. N Y Acad Sci. 995, 48 58.
    • (2003) Ann. N Y Acad Sci. , vol.995 , pp. 48-58
    • Wankell, M.1    Werner, S.2    Alzheimer, C.3
  • 40
    • 6944242126 scopus 로고    scopus 로고
    • Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members
    • Weinreb O., Bar-Am O., Amit T., Chillag-Talmor O. Youdim M. B. (2004) Neuroprotection via pro-survival protein kinase C isoforms associated with Bcl-2 family members. FASEB J. 18, 1471 1473.
    • (2004) FASEB J. , vol.18 , pp. 1471-1473
    • Weinreb, O.1    Bar-Am, O.2    Amit, T.3    Chillag-Talmor, O.4    Youdim, M.B.5
  • 41
    • 33744515391 scopus 로고    scopus 로고
    • Roles of activin in tissue repair, fibrosis, and inflammatory disease
    • Werner S. Alzheimer C. (2006) Roles of activin in tissue repair, fibrosis, and inflammatory disease. Cytokine Growth Factor Rev. 17, 157 171.
    • (2006) Cytokine Growth Factor Rev. , vol.17 , pp. 157-171
    • Werner, S.1    Alzheimer, C.2
  • 42
    • 0033600478 scopus 로고    scopus 로고
    • Expression of the activin axis and neuronal rescue effects of recombinant activin a following hypoxic-ischemic brain injury in the infant rat
    • Wu D. D., Lai M., Hughes P. E., Sirimanne E., Gluckman P. D. Williams C. E. (1999) Expression of the activin axis and neuronal rescue effects of recombinant activin A following hypoxic-ischemic brain injury in the infant rat. Brain Res. 835, 369 378.
    • (1999) Brain Res. , vol.835 , pp. 369-378
    • Wu, D.D.1    Lai, M.2    Hughes, P.E.3    Sirimanne, E.4    Gluckman, P.D.5    Williams, C.E.6
  • 43
    • 0034641936 scopus 로고    scopus 로고
    • Apoptosis in the nervous system
    • Yuan J. Yankner B. A. (2000) Apoptosis in the nervous system. Nature 407, 802 809.
    • (2000) Nature , vol.407 , pp. 802-809
    • Yuan, J.1    Yankner, B.A.2
  • 44
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
    • Zha J., Harada H., Yang E., Jockel J. Korsmeyer S. J. (1996) Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L). Cell 87, 619 628.
    • (1996) Cell , vol.87 , pp. 619-628
    • Zha, J.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5
  • 45
    • 0034651876 scopus 로고    scopus 로고
    • Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathway
    • Zhang L., Himi T., Morita I. Murota S. (2000) Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathway. J. Neurosci. Res. 59, 489 496.
    • (2000) J. Neurosci. Res. , vol.59 , pp. 489-496
    • Zhang, L.1    Himi, T.2    Morita, I.3    Murota, S.4
  • 46


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