Age, gender, and skeletal variation in bone marrow composition: A preliminary study at 3.0 Tesla

Journal of Magnetic Resonance Imaging

Volumn 26, Issue 3, 2007, Pages 787-793

  Liney, Gary P ^a   Bernard, Clare P ^a   Manton, David J ^a   Turnbull, Lindsay W ^a   Langton, Chris M ^a  

^a HULL ROYAL INFIRMARY   (United Kingdom)

Author keywords

Bone marrow; Fat fraction; Fat imaging; MR spectroscopy; Osteoporosis

Indexed keywords

ADULT; AGE DISTRIBUTION; ARTICLE; BONE DENSITY; BONE DEVELOPMENT; BONE MARROW; CALCANEUS; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DUAL ENERGY X RAY ABSORPTIOMETRY; FAT CONTENT; FEMALE; HUMAN; HUMAN EXPERIMENT; LUMBAR SPINE; MALE; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OSTEOPOROSIS; POPULATION DISTRIBUTION; PRIORITY JOURNAL; QUALITY CONTROL; SEX DIFFERENCE; VERTEBRA BODY; ADIPOSE TISSUE; ADOLESCENT; AGE; BONE; CHILD; LUMBAR VERTEBRA; METABOLISM; METHODOLOGY; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY;

ADIPOSE TISSUE; ADOLESCENT; ADULT; AGE FACTORS; BONE AND BONES; BONE MARROW; CHILD; FEMALE; HUMANS; LUMBAR VERTEBRAE; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MIDDLE AGED; SEX FACTORS;

EID: 35248855497     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.21072     Document Type: Article

References (23)

1. Eriksson SA, Isberg BO, Lindgren JU. Prediction of vertebral strength by dual photon absorptiometry and qualitative computed tomography. Calcif Tissue Int 1989;44:243-250.
2. Piney A. The anatomy of bone marrow. Br Med J 1922;2:792-795.
3. Vogler JB, Murphy WA. Bone marrow imaging. Radiology 1988;168:679-693.
4. Okada Y, Aoki S, Barkovich AJ, et al. Cranial bone marrow in children: Assessment of normal development with MR imaging. Radiology 1989;171:161-164.
5. Moore SG, Dawson KL. Red and yellow marrow in the femur: age-related changes in appearance at MR imaging. Radiology 1990;175:219-223.
6. Ricci C, Cova M, Kang YS, et al. Normal age-related patterns of cellular and fatty bone marrow distribution in the axial skeleton: MR imaging study. Radiology 1990;177:83-88.
7. Jaramillo D, Laor T, Hoffer FA, et al. Epiphyseal marrow in infancy: MR imaging. Radiology 1991;180:809-812.
8. Dawson KL, Moore SG, Rowland JM. Age-related marrow changes in the pelvis: MR and anatomic findings. Radiology 1992;183:47-51.
9. De Bisschop E, Luypaert R, Louis O, Osteaux M. Fat fraction of lumbar bone marrow using in vivo proton nuclear magnetic resonance spectroscopy. Bone 1993;14:133-136.
10. Schellinger D, Lin CS, Fertikh D, et al. Normal lumbar vertebrae: anatomic, age and sex variance in subjects at proton MR spectroscopy - initial experience. Radiology 2000;215:910-916.
11. Kugel H, Jung C, Schulte O, Heindel W. Age and sex specific differences in the 1H-spectrum of vertebral bone marrow. J Magn Reson Imaging 2001;13:263-268.
12. Vande Berg BC, Lecouvert FE, Malghem J. Sex-related difference in marrow conversion in the proximal femur: does it exist? Radiology 1998;209:587-588.
13. Jenkins JPR, Stehling M, Sivewright G, Hickey DS, Hillier VF, Ishwerwood I. Quantitative magnetic resonance imaging of vertebral bodies: aT1 and T2 study. Magn Reson Imaging 1989;7:17-23.
14. Schellinger D, Lin CS, Hatipoglu HG, Fertikh D. Potential value of proton MR spectroscopy in determining bone weakness. Am J Neuroradiol 2001;22:1620-1627.
15. Schellinger D, Lin CS, Lim J, Hatipoglu HG, Pezzullo JC, Singer AJ. Bone marrow fat and bone mineral density on proton MR spectroscopy and dual energy x-ray absorptiometry: Their ratio as a new indicator of bone weakening. AJR Am J Roentgenol 2004;183:1761-1765.
16. Jagannathan NR, Singh M, Govindaraju V, et al. Volume localised in vivo proton MR spectroscopy of breast carcinoma: variation of water-fat ratio in patients receiving chemotherapy. NMR Biomed 1998;11:414-422.
17. Hussain HK, Chenevert TL, Londy FJ, et al. Hepatic fat fraction: MR imaging for quantitative measurement and display - early experience. Radiology 2005;237:1048.
18. Reeder SB, Huanzhou Y, Johnson JW, et al. T1- and T2-weighted fast spin-echo imaging of the brachial plexus and cervical spine with IDEAL water-fat separation. J Magn Reson Imaging 2006;24:825-832.
19. Traber F, Block W, Layer G, et al. Determination of 1H relaxation time of water in human bone marrow by fat-suppressed turbo spin echo in comparison to MR spectroscopic methods. J Magn Reson Imaging 1996;6:541-548.
20. Yeung DKW, Griffith JF, Antonio GE, Lee FKH, Woo J, Leung PC. Osteoporosis is associated with increased marrow fat content and decreased marrow fat unsaturatioin: a proton MR spectroscopic study. J Magn Reson Imaging 2005;22:279-285.
21. Shin TT, Liu H, Chang C, Wei A, Shen L, Yang P. Correlation of MR lumbar spine bone marrow perfusion with bone mineral density in female subjects. Radiology 2004;233:121-128.
22. Chen W, Shih TT. Correlation between the bone marrow blood perfusion and lipid water content on the lumbar spine in female subjects. J Magn Reson Imaging 2006;24:176-181.
23. Griffith JF, Yeung DKW, Antonio GE, et al. Vertebral bone mineral density, marrow perfusion and fat content in healthy men and men with osteoporosis: dynamic contrast-enhanced MR imaging and MR spectroscopy. Radiology 2005;236:945-951.