A mutational study of transmembrane helix-helix interactions

Biochimie

Volumn 89, Issue 11, 2007, Pages 1433-1437

  Prodöhl, Alexander ^a   Weber, Mathias ^a   Dreher, Carolin ^a   Schneider, Dirk ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Assembly; Cytochrome; Detergent; Protein folding; SDS; Transmembrane helix

Indexed keywords

CYTOCHROME;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ARTICLE; CELL MEMBRANE; COMPARATIVE STUDY; DIMERIZATION; MOLECULAR INTERACTION; MOLECULAR STABILITY; MUTATIONAL ANALYSIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; THERMODYNAMICS;

AMINO ACID SEQUENCE; CELL MEMBRANE; CYTOCHROME B GROUP; DIMERIZATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; MEMBRANE PROTEINS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS;

EID: 35248840065     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2007.06.006     Document Type: Article

References (19)

1. Fisher L.E., Engelman D.M., and Sturgis J.N. Effect of detergents on the association of the glycophorin a transmembrane helix. Biophys. J. 85 (2003) 3097-3105
2. Fleming K.G., and Engelman D.M. Specificity in transmembrane helix-helix interactions can define a hierarchy of stability for sequence variants. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 14340-14344
3. Russ W.P., and Engelman D.M. TOXCAT: a measure of transmembrane helix association in a biological membrane. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 863-868
4. Lemmon M.A., Flanagan J.M., Treutlein H.R., Zhang J., and Engelman D.M. Sequence specificity in the dimerization of transmembrane alpha-helices. Biochemistry 31 (1992) 12719-12725
5. Sulistijo E.S., and Mackenzie K.R. Sequence dependence of BNIP3 transmembrane domain dimerization implicates side-chain hydrogen bonding and a tandem GxxxG motif in specific helix-helix interactions. J. Mol. Biol. 364 (2006) 974-990
6. Kobus F.J., and Fleming K.G. The GxxxG-containing transmembrane domain of the CCK4 oncogene does not encode preferential self-interactions. Biochemistry 44 (2005) 1464-1470
7. Renthal R. An unfolding story of helical transmembrane proteins. Biochemistry 45 (2006) 14559-14566
8. Stewart D.H., and Brudvig G.W. Cytochrome b559 of photosystem II. Biochim. Biophys. Acta 1367 (1998) 63-87
9. Francke C., Loyal R., Ohad I., and Haehnel W. In vitro assembly of a beta2 cytochrome b559-like complex from the chemically synthesised beta-subunit encoded by the Synechocystis sp. 6803 psbF gene. FEBS Lett. 442 (1999) 75-78
10. Prodöhl A., Volkmer T., Finger C., and Schneider D. Defining the structural basis for assembly of a transmembrane cytochrome. J. Mol. Biol. 350 (2005) 744-756
11. Schneider D., and Engelman D.M. GALLEX, a measurement of heterologous association of transmembrane helices in a biological membrane. J. Biol. Chem. 278 (2003) 3105-3111
12. Finger C., Volkmer T., Prodöhl A., Otzen D.E., Engelman D.M., and Schneider D. The stability of transmembrane helix interactions measured in a biological membrane. J. Mol. Biol. 358 (2006) 1221-1228
13. Schneider D., Finger C., Prodöhl A., and Volkmer T. From interactions of single transmembrane helices to folding of -helical membrane proteins: analyzing transmembrane helix-helix interactions in bacteria. Curr. Protein Pept. Sci. 8 (2007) 45-61
14. Zhou F.X., Merianos H.J., Brunger A.T., and Engelman D.M. Polar residues drive association of polyleucine transmembrane helices. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 2250-2255
15. Doura A.K., and Fleming K.G. Complex interactions at the helix-helix interface stabilize the glycophorin a transmembrane dimer. J. Mol. Biol. 343 (2004) 1487-1497
16. MacKenzie K.R., and Engelman D.M. Structure-based prediction of the stability of transmembrane helix-helix interactions: the sequence dependence of glycophorin A dimerization. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 3583-3590
17. MacKenzie K.R., Prestegard J.H., and Engelman D.M. A transmembrane helix dimer: structure and implications. Science 276 (1997) 131-133
18. Senes A., Ubarretxena-Belandia I., and Engelman D.M. The Calpha-H⋯O hydrogen bond: a determinant of stability and specificity in transmembrane helix interactions. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 9056-9061
19. Koch H.G., and Schneider D. Assembly and stability of transmembrane cytochromes. Curr. Chem. Biol. 1 (2007) 59-74