-
1
-
-
0036458013
-
Herbal medication: Potential for adverse interactions with analgesic drugs
-
Abebe W 2002. Herbal medication: potential for adverse interactions with analgesic drugs. J Clin Pharm Ther 27: 391-401.
-
(2002)
J Clin Pharm Ther
, vol.27
, pp. 391-401
-
-
Abebe, W.1
-
3
-
-
26244454933
-
Flutamide-induced hepatotoxicity during treatment of acne - A case report
-
Amorim MFD, Amorim WPD, Duques P, Amorim PD, Vasconcelos JR 2005. Flutamide-induced hepatotoxicity during treatment of acne - A case report. An Bras Dermatol 80: 381-384.
-
(2005)
An Bras Dermatol
, vol.80
, pp. 381-384
-
-
Amorim, M.F.D.1
Amorim, W.P.D.2
Duques, P.3
Amorim, P.D.4
Vasconcelos, J.R.5
-
4
-
-
0035661051
-
Pharmacological treatment of generalized anxiety disorder: Future perspectives
-
Andreatini R, Boerngen-Lacerda R, Filho DZ 2001. Pharmacological treatment of generalized anxiety disorder: future perspectives. Rev Bras Psiquiatr 23: 233-242.
-
(2001)
Rev Bras Psiquiatr
, vol.23
, pp. 233-242
-
-
Andreatini, R.1
Boerngen-Lacerda, R.2
Filho, D.Z.3
-
5
-
-
1842431946
-
Kava hepatotoxicity: Are we any closer to the truth?
-
Anke J, Ramzan I 2004. Kava hepatotoxicity: Are we any closer to the truth? Planta Med 70: 193-196.
-
(2004)
Planta Med
, vol.70
, pp. 193-196
-
-
Anke, J.1
Ramzan, I.2
-
7
-
-
0037134254
-
Kava-kava and anxiety: Growing knowledge about the efficacy and safety
-
Bilia AR, Gallori S, Vincieri FF 2002. Kava-kava and anxiety: growing knowledge about the efficacy and safety. Life Sci 70: 2581-2597.
-
(2002)
Life Sci
, vol.70
, pp. 2581-2597
-
-
Bilia, A.R.1
Gallori, S.2
Vincieri, F.F.3
-
9
-
-
11144251633
-
Chaos in hepatology: Do we know what our patients are taking?
-
Blendis L 2005. Chaos in hepatology: do we know what our patients are taking?. Gastroenterol 128: 240.
-
(2005)
Gastroenterol
, vol.128
, pp. 240
-
-
Blendis, L.1
-
11
-
-
1842479653
-
Kava kava: Examining new reports of toxicity
-
Clouatre DL 2004. Kava kava: examining new reports of toxicity. Toxicol Lett 150: 85-96.
-
(2004)
Toxicol Lett
, vol.150
, pp. 85-96
-
-
Clouatre, D.L.1
-
12
-
-
0345564969
-
Liver function test abnormalities in users of aqueous kava extracts
-
Clough AR, Bailie RS, Currie B 2003. Liver function test abnormalities in users of aqueous kava extracts. J Toxicol-Clin Toxic 41: 821-829.
-
(2003)
J Toxicol-Clin Toxic
, vol.41
, pp. 821-829
-
-
Clough, A.R.1
Bailie, R.S.2
Currie, B.3
-
13
-
-
85039133688
-
-
Cordeiro CHG, Chung MC, Sacramento LVS 2005. Interações medicamentosas de fitoterápicos e fãrmacos: Hypericum perforatum e Piper methysticum. Rev Bras Farmacogn 13: 272-278.
-
Cordeiro CHG, Chung MC, Sacramento LVS 2005. Interações medicamentosas de fitoterápicos e fãrmacos: Hypericum perforatum e Piper methysticum. Rev Bras Farmacogn 13: 272-278.
-
-
-
-
14
-
-
4143093675
-
Composition and biological activity of traditional and commercial kava extracts
-
Côté CS, Kor C, Cohen J, Auclari K 2004. Composition and biological activity of traditional and commercial kava extracts. Biol Biophy Res Comm 322: 147-152.
-
(2004)
Biol Biophy Res Comm
, vol.322
, pp. 147-152
-
-
Côté, C.S.1
Kor, C.2
Cohen, J.3
Auclari, K.4
-
15
-
-
0037137560
-
Drug Therapy: Herbal remedies
-
De Smet PAGM 2002. Drug Therapy: herbal remedies. N Engl J Med 347: 2046-2056.
-
(2002)
N Engl J Med
, vol.347
, pp. 2046-2056
-
-
De Smet, P.A.G.M.1
-
17
-
-
0033947905
-
Myoglobinuria after ingestion of extracts of guarana, Ginkgo biloba and kava
-
Donadio V, Bonsi P, Zele I, Monari L, Liguori R, Vetrugno R, Albani F, Montagna P 2000. Myoglobinuria after ingestion of extracts of guarana, Ginkgo biloba and kava. Neural Sci 21: 124.
-
(2000)
Neural Sci
, vol.21
, pp. 124
-
-
Donadio, V.1
Bonsi, P.2
Zele, I.3
Monari, L.4
Liguori, R.5
Vetrugno, R.6
Albani, F.7
Montagna, P.8
-
18
-
-
0036081810
-
Phytotherapeutic drugs in gastroenterology and hepatology
-
Dufour JF, St-Pierre MV 2002. Phytotherapeutic drugs in gastroenterology and hepatology. Ther Umsch 59: 313-316.
-
(2002)
Ther Umsch
, vol.59
, pp. 313-316
-
-
Dufour, J.F.1
St-Pierre, M.V.2
-
19
-
-
0033749231
-
Adverse effects of herbal drugs in dermatology
-
Ernst E 2000. Adverse effects of herbal drugs in dermatology. Brit J Dermatol 43: 923.
-
(2000)
Brit J Dermatol
, vol.43
, pp. 923
-
-
Ernst, E.1
-
20
-
-
0037172395
-
Safety concerns about kava
-
Ernst E 2002. Safety concerns about kava. Lancet 359: 1865.
-
(2002)
Lancet
, vol.359
, pp. 1865
-
-
Ernst, E.1
-
21
-
-
0141517488
-
Systematic review: Hepatotoxic events associated with herbal medicinal products
-
Ernst E, Pittler MH 2003. Systematic review: hepatotoxic events associated with herbal medicinal products. Alim Pharm Ther 18: 451-471.
-
(2003)
Alim Pharm Ther
, vol.18
, pp. 451-471
-
-
Ernst, E.1
Pittler, M.H.2
-
22
-
-
0037354511
-
Anxiolytic properties of Piper methysticum extract samples and fractions in the chick social-separation- stress procedure
-
Feltenstein MW, Lambdin LC, Ganzera M, Ranjith H, Dharmaratne W, Nanayakkara NP, Khan IA, Sufka KJ 2003. Anxiolytic properties of Piper methysticum extract samples and fractions in the chick social-separation- stress procedure. Phytother Res 17: 210-216.
-
(2003)
Phytother Res
, vol.17
, pp. 210-216
-
-
Feltenstein, M.W.1
Lambdin, L.C.2
Ganzera, M.3
Ranjith, H.4
Dharmaratne, W.5
Nanayakkara, N.P.6
Khan, I.A.7
Sufka, K.J.8
-
23
-
-
0011361597
-
-
Food and Drug Administration FDA, Center for Food Safety and Applied Nutrition, U. S. Food and Drug Administration, Dietary Supplements
-
Food and Drug Administration (FDA) 2002. Kava-containing dietary supplements may be associated with severe liver injury. Center for Food Safety and Applied Nutrition, U. S. Food and Drug Administration, Dietary Supplements.
-
(2002)
Kava-containing dietary supplements may be associated with severe liver injury
-
-
-
24
-
-
0035512382
-
Herb-drug interactions: Review and assessment of report reliability
-
Fugh-Berman A, Ernst E 2001. Herb-drug interactions: Review and assessment of report reliability. Brit J Clin Pharmacol 52: 587-595.
-
(2001)
Brit J Clin Pharmacol
, vol.52
, pp. 587-595
-
-
Fugh-Berman, A.1
Ernst, E.2
-
25
-
-
0037650196
-
Fatal fulminant hepatic failure induced by a natural therapy containing kava
-
Gow PJ, Connelly NJ, Hill RL, Crowley P, Angus PW 2003. Fatal fulminant hepatic failure induced by a natural therapy containing kava. Med J Aust 178: 442-443.
-
(2003)
Med J Aust
, vol.178
, pp. 442-443
-
-
Gow, P.J.1
Connelly, N.J.2
Hill, R.L.3
Crowley, P.4
Angus, P.W.5
-
26
-
-
0032906281
-
Kawain limits excitation in CA 1 pyramidal neurons of rats by modulating ionic currents and attenuating excitatory synaptic transmission
-
Grunze H, Walder J 1999. Kawain limits excitation in CA 1 pyramidal neurons of rats by modulating ionic currents and attenuating excitatory synaptic transmission. Hum Psychopharmacol Clin Exp 14: 63-66.
-
(1999)
Hum Psychopharmacol Clin Exp
, vol.14
, pp. 63-66
-
-
Grunze, H.1
Walder, J.2
-
27
-
-
0033901357
-
Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice
-
Hentze H, Gantner F, Kolb SA, Wendel A 2000. Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice. Am J Path 156: 2045-2056.
-
(2000)
Am J Path
, vol.156
, pp. 2045-2056
-
-
Hentze, H.1
Gantner, F.2
Kolb, S.A.3
Wendel, A.4
-
29
-
-
0037974273
-
Identification of novel electrophilic metabolites of Piper methysticum Forst (Kava)
-
Johnson BM, Qiu HX, Zhang S, Zhang F, Burdette JE, Yu L, Boltom JL, Breemen RB 2003. Identification of novel electrophilic metabolites of Piper methysticum Forst (Kava). Chem Res Toxicol 16: 733-740.
-
(2003)
Chem Res Toxicol
, vol.16
, pp. 733-740
-
-
Johnson, B.M.1
Qiu, H.X.2
Zhang, S.3
Zhang, F.4
Burdette, J.E.5
Yu, L.6
Boltom, J.L.7
Breemen, R.B.8
-
30
-
-
0035192830
-
Causality assessment versus guilt-by-association in drug hepatotoxicity
-
Kaplowitz N 2001. Causality assessment versus guilt-by-association in drug hepatotoxicity. Hepatology 33: 308-310.
-
(2001)
Hepatology
, vol.33
, pp. 308-310
-
-
Kaplowitz, N.1
-
31
-
-
0036257307
-
Biochemical and cellular mechanisms of toxic liver injury
-
Kaplowitz N 2002. Biochemical and cellular mechanisms of toxic liver injury. Semin Liver Dis 22: 137-144.
-
(2002)
Semin Liver Dis
, vol.22
, pp. 137-144
-
-
Kaplowitz, N.1
-
32
-
-
0035823136
-
Fulminant liver failure after administration of the herbal antidepressant Kava-Kava
-
Kraft M, Spahn TW, Menzel J, Senninger N, Dietl KH, Herbst H, Domschke W, Lerch MM 2001. Fulminant liver failure after administration of the herbal antidepressant Kava-Kava. Dtsch Med Wochenschr 126: 970-972.
-
(2001)
Dtsch Med Wochenschr
, vol.126
, pp. 970-972
-
-
Kraft, M.1
Spahn, T.W.2
Menzel, J.3
Senninger, N.4
Dietl, K.H.5
Herbst, H.6
Domschke, W.7
Lerch, M.M.8
-
33
-
-
0001013981
-
The origin and distribution of kava (Piper methysticum Frost. f. and Piper wichmanii C. DC., Piperaceae) a phytochemical approach
-
Lebot V, Levesque J 1989. The origin and distribution of kava (Piper methysticum Frost. f. and Piper wichmanii C. DC., Piperaceae) a phytochemical approach. Allertonia 5: 223-281.
-
(1989)
Allertonia
, vol.5
, pp. 223-281
-
-
Lebot, V.1
Levesque, J.2
-
34
-
-
0041342015
-
Drug-induced hepatotoxicity
-
Lee WM 2003. Drug-induced hepatotoxicity. N Engl J Med 349: 474-485.
-
(2003)
N Engl J Med
, vol.349
, pp. 474-485
-
-
Lee, W.M.1
-
35
-
-
0346422376
-
Clinical efficacy of kava extract WSR 1490 in sleep disturbances associated with anxiety disorders. Results of a multicenter, randomized, placebo-controlled, double-blind clinical trial
-
Lehrl S 2004. Clinical efficacy of kava extract WSR 1490 in sleep disturbances associated with anxiety disorders. Results of a multicenter, randomized, placebo-controlled, double-blind clinical trial. J Affect Disorders 78: 101-110.
-
(2004)
J Affect Disorders
, vol.78
, pp. 101-110
-
-
Lehrl, S.1
-
36
-
-
0029994146
-
Hepatotoxicity of the herbal medicine germander: Metabolic activation of its furano diterpenoids by cytochrome P450 3A Depletes cytoskeleton-associated protein thiols and forms plasma membrane blebs in rat hepatocytes
-
Lekehal M, Pessayre D, Lereau JM, Moulis C, Fouraste I, Fau D 1996. Hepatotoxicity of the herbal medicine germander: metabolic activation of its furano diterpenoids by cytochrome P450 3A Depletes cytoskeleton-associated protein thiols and forms plasma membrane blebs in rat hepatocytes. Hepatology 24: 212-2188.
-
(1996)
Hepatology
, vol.24
, pp. 212-2188
-
-
Lekehal, M.1
Pessayre, D.2
Lereau, J.M.3
Moulis, C.4
Fouraste, I.5
Fau, D.6
-
37
-
-
85039089555
-
-
Maddrey WC 2003. Clinicophathological patterns of drug-induced liver disease. In: Kaplowitz N, Deleve LD. Drug induced Liver Disease. New York: Marcel Dekker, Inc. 724p.
-
Maddrey WC 2003. Clinicophathological patterns of drug-induced liver disease. In: Kaplowitz N, Deleve LD. Drug induced Liver Disease. New York: Marcel Dekker, Inc. 724p.
-
-
-
-
38
-
-
15444368643
-
Drug-induced hepatotoxicity
-
Maddrey WC 2005. Drug-induced hepatotoxicity. J Clin Gastroenterol 39(S2): 83-89.
-
(2005)
J Clin Gastroenterol
, vol.39
, Issue.S2
, pp. 83-89
-
-
Maddrey, W.C.1
-
40
-
-
0036842023
-
Inhibition of human cytochrome P450 activities by kava extract and kavalactones
-
Mathews JM, Etheridge AS, Black SR 2002. Inhibition of human cytochrome P450 activities by kava extract and kavalactones. Drug Metab Dispos 30: 1153-1157.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1153-1157
-
-
Mathews, J.M.1
Etheridge, A.S.2
Black, S.R.3
-
41
-
-
85039131333
-
Medicines Control Agency
-
MCA, December 20, Accessed October 12, 2005, at
-
MCA 2005. Medicines Control Agency. Investigation of Kava Kava Leads to Ban Following Voluntary Withdrawal. December 20, 2002. Accessed October 12, 2005, at http://www.mca.gov.uk/whatsnew/pressreleases/Kava211202.pdf.
-
(2002)
Investigation of Kava Kava Leads to Ban Following Voluntary Withdrawal
-
-
-
42
-
-
0036460858
-
Life-threatening parkinsonism induced by kava-kava
-
Meseguer E, Taboada R, Sánchez V, Mena MA, Campos V, Yébenes JG 2002. Life-threatening parkinsonism induced by kava-kava. Mov Disorders 17: 195-196.
-
(2002)
Mov Disorders
, vol.17
, pp. 195-196
-
-
Meseguer, E.1
Taboada, R.2
Sánchez, V.3
Mena, M.A.4
Campos, V.5
Yébenes, J.G.6
-
43
-
-
0032501120
-
Herbal medicinals: Selected clinical considerations focusing on known or potential drug-herb interactions
-
Miller LG 1998. Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions. Arch Intern Med 158: 2200-2211.
-
(1998)
Arch Intern Med
, vol.158
, pp. 2200-2211
-
-
Miller, L.G.1
-
44
-
-
33745513992
-
Acute hepatitis due to kava-kava and St John's Wort: An immune-mediated mechanism?
-
Musch E, Chrissafidou A, Malek M 2006. Acute hepatitis due to kava-kava and St John's Wort: an immune-mediated mechanism? Dtsch Med Wochenschr 131: 1214-1217.
-
(2006)
Dtsch Med Wochenschr
, vol.131
, pp. 1214-1217
-
-
Musch, E.1
Chrissafidou, A.2
Malek, M.3
-
45
-
-
0019799332
-
A method for estimating the probability of adverse drug reactions
-
Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, Janecek E, Domecq C, Greenblatt DJ 1981. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 30: 239-245.
-
(1981)
Clin Pharmacol Ther
, vol.30
, pp. 239-245
-
-
Naranjo, C.A.1
Busto, U.2
Sellers, E.M.3
Sandor, P.4
Ruiz, I.5
Roberts, E.A.6
Janecek, E.7
Domecq, C.8
Greenblatt, D.J.9
-
46
-
-
32644469104
-
Drug-related Hepatotoxicity
-
Navarro VJ, Senior JR 2006. Drug-related Hepatotoxicity. N Engl J Med 354: 131-739.
-
(2006)
N Engl J Med
, vol.354
, pp. 131-739
-
-
Navarro, V.J.1
Senior, J.R.2
-
47
-
-
2442710270
-
In vitro toxicity of kava alkaloid, pipermethystine, in HepG2 cells compared to kavalactones
-
Nerurkar PV, Dragull K, Tang CS 2004. In vitro toxicity of kava alkaloid, pipermethystine, in HepG2 cells compared to kavalactones. Toxicol Sci 79: 106-111.
-
(2004)
Toxicol Sci
, vol.79
, pp. 106-111
-
-
Nerurkar, P.V.1
Dragull, K.2
Tang, C.S.3
-
48
-
-
0026466184
-
Acute hepatitis caused by wild germander. Hepatotoxicity of herbal remedies. Two cases
-
Pauwels A, Thierman-Duffaud D, Azanowsky JM, Loiseau D, Biour M, Levy VG 1992. Acute hepatitis caused by wild germander. Hepatotoxicity of herbal remedies. Two cases. Gastroenterol Clin Biol 16: 92-95.
-
(1992)
Gastroenterol Clin Biol
, vol.16
, pp. 92-95
-
-
Pauwels, A.1
Thierman-Duffaud, D.2
Azanowsky, J.M.3
Loiseau, D.4
Biour, M.5
Levy, V.G.6
-
49
-
-
0033971030
-
Efficacy of kava extract for treating anxiety: Systematic review and meta-analysis
-
Pittler MH, Ernst E 2000. Efficacy of kava extract for treating anxiety: systematic review and meta-analysis. J Clin Psychopharmacol 20: 84-89.
-
(2000)
J Clin Psychopharmacol
, vol.20
, pp. 84-89
-
-
Pittler, M.H.1
Ernst, E.2
-
52
-
-
0043263837
-
Hepatic injury due to traditional aqueous extracts of kava root in New Caledonia
-
Russmann S, Barguil Y, Cabalion P, Kritsanida M, Duhet D, Lauterburg B 2003. Hepatic injury due to traditional aqueous extracts of kava root in New Caledonia. Eur J Gastroenterol Hepatol 15: 1033-1036.
-
(2003)
Eur J Gastroenterol Hepatol
, vol.15
, pp. 1033-1036
-
-
Russmann, S.1
Barguil, Y.2
Cabalion, P.3
Kritsanida, M.4
Duhet, D.5
Lauterburg, B.6
-
53
-
-
33746832671
-
-
Accessed: June 29, 2006, at
-
Schmidt M 2006. Is kava really hepatotoxic? Accessed: June 29, 2006, at http://www.taxtyranny.ca/images/HTML/KavaKava/Articles/KavaReview.pdf.
-
(2006)
Is kava really hepatotoxic
-
-
Schmidt, M.1
-
55
-
-
0037826020
-
Aqueous kava extracts do not affect liver function tests in rats
-
Singh YN, Devkota AK 2003. Aqueous kava extracts do not affect liver function tests in rats. Planta Med 69: 496-499.
-
(2003)
Planta Med
, vol.69
, pp. 496-499
-
-
Singh, Y.N.1
Devkota, A.K.2
-
56
-
-
0036100226
-
Identification of factors determining kava lactone content and chemotype in kava (Piper methysticum Forst, f.)
-
Siméoni P, Lebot V 2002. Identification of factors determining kava lactone content and chemotype in kava (Piper methysticum Forst, f.). Biochem Syst Ecol 30: 413-424.
-
(2002)
Biochem Syst Ecol
, vol.30
, pp. 413-424
-
-
Siméoni, P.1
Lebot, V.2
-
57
-
-
0037555313
-
Herbal medicines and epilepsy: The potential for benefit and adverse effects
-
Spinella M 2001. Herbal medicines and epilepsy: The potential for benefit and adverse effects. Epilepsy Behav 2: 524-532.
-
(2001)
Epilepsy Behav
, vol.2
, pp. 524-532
-
-
Spinella, M.1
-
58
-
-
0036261506
-
A Systematic review of the safety of kava extract in the treatment of anxiety
-
Stevinson C, Alyson H, Ernst E 2002. A Systematic review of the safety of kava extract in the treatment of anxiety. Drug Safety 25: 251-261.
-
(2002)
Drug Safety
, vol.25
, pp. 251-261
-
-
Stevinson, C.1
Alyson, H.2
Ernst, E.3
-
59
-
-
0037973477
-
Hepatitis induced by Kava (Piper methysticum rhizoma)
-
Stickel F, Baumüller HM, Seitz K, Vasilakis D, Seitz G, Seitz HK, Schuppan D 2003. Hepatitis induced by Kava (Piper methysticum rhizoma). J Hepatol 39: 62-67.
-
(2003)
J Hepatol
, vol.39
, pp. 62-67
-
-
Stickel, F.1
Baumüller, H.M.2
Seitz, K.3
Vasilakis, D.4
Seitz, G.5
Seitz, H.K.6
Schuppan, D.7
-
61
-
-
0037532579
-
Kava extracts: Safety and risks including rare hepatotoxicity
-
Teschke R, Gaus W, Loew D 2003. Kava extracts: Safety and risks including rare hepatotoxicity. Phytomedicine 10: 440-446.
-
(2003)
Phytomedicine
, vol.10
, pp. 440-446
-
-
Teschke, R.1
Gaus, W.2
Loew, D.3
-
62
-
-
22344442003
-
Medicinal plants for insomnia: A review of their pharmacology, efficacy and tolerability
-
Wheatley D 2005. Medicinal plants for insomnia: a review of their pharmacology, efficacy and tolerability. J Psychopharmacol 4: 414-421.
-
(2005)
J Psychopharmacol
, vol.4
, pp. 414-421
-
-
Wheatley, D.1
-
63
-
-
0141839116
-
Kava lactones and the kava-kava controversy
-
Whitton PA, Lau A, Salisbury A, Whitehouse JS, Evans CS 2003. Kava lactones and the kava-kava controversy. Phytochemistry 64: 673-679.
-
(2003)
Phytochemistry
, vol.64
, pp. 673-679
-
-
Whitton, P.A.1
Lau, A.2
Salisbury, A.3
Whitehouse, J.S.4
Evans, C.S.5
-
64
-
-
19444376971
-
Drug metabolism and variability among patients in drug response
-
Wilkinson GR 2005. Drug metabolism and variability among patients in drug response. N Engl J Med 352: 2211-2221.
-
(2005)
N Engl J Med
, vol.352
, pp. 2211-2221
-
-
Wilkinson, G.R.1
-
65
-
-
0037911516
-
Isolation and synthesis of TNF-alpha release inhibitors from Fijian kawa (Piper methysticum)
-
Yamada M, Kohno T, Asakawa Y 2003. Isolation and synthesis of TNF-alpha release inhibitors from Fijian kawa (Piper methysticum). Phytomedicine 10: 309-317.
-
(2003)
Phytomedicine
, vol.10
, pp. 309-317
-
-
Yamada, M.1
Kohno, T.2
Asakawa, Y.3
|