Effect of perindopril on coronary remodelling: Insights from a multicentre, randomized study

European Heart Journal

Volumn 28, Issue 19, 2007, Pages 2326-2331

  Rodriguez Granillo, Gastón A ^a,b   De Winter, Sebastiaan ^a   Bruining, Nico ^a   Ligthart, Jurgen M R ^a   García García, Héctor M ^a   Valgimigli, Marco ^a   De Feyter, Pim J ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b Sanatorio Otamendi y Miroli   (Argentina)

Author keywords

ACE inhibitor; Atherosclerosis; EUROPA; Progression; Regression; Remodelling

Indexed keywords

ANTILIPEMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; NITRATE; PERINDOPRIL; THROMBOCYTE SLOWING FACTOR;

ADULT; ARTICLE; ATHEROSCLEROTIC PLAQUE; BLOOD VESSEL WALL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY REMODELLING; DRUG EFFICACY; FEMALE; FOLLOW UP; HEART FAILURE; HUMAN; INTRAVASCULAR ULTRASOUND; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CARDIOVASCULAR DISEASES; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; DISEASE PROGRESSION; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; OBSERVER VARIATION; PERINDOPRIL; REGRESSION ANALYSIS; TREATMENT OUTCOME; ULTRASONOGRAPHY, INTERVENTIONAL; VENTRICULAR REMODELING;

EID: 35148846084     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehm255     Document Type: Article

References (25)

1. Glagov S, Weisenberg E, Zarins CK, Stankunavicius R, Kolettis GJ. Compensatory enlargement of human atherosclerotic coronary arteries. New Engl J Med 1987;316:1371-1375.
2. Pasterkamp G, Schoneveld AH, van der Wal AC, Haudenschild CC, Clarijs RJ, Becker AE, Hillen B, Borst C. Relation of arterial geometry to luminal narrowing and histologic markers for plaque vulnerability: the remodeling paradox. J Am Coll Cardiol 1998;32:655-662.
3. Varnava AM, Mills PG, Davies MJ. Relationship between coronary artery remodeling and plaque vulnerability. Circulation 2002;105:939-943.
4. Burke AP, Kolodgie FD, Farb A, Weber D, Virmani R. Morphological predictors of arterial remodeling in coronary atherosclerosis. Circulation 2002;105:297-303.
5. Rodriguez-Granillo GA, Serruys PW, Garcia-Garcia HM, Aoki J, Valgimigli M, van Mieghem CA, Mc Fadden E, de Jaegere PP, de Feyter P. Coronary artery remodelling is related to plaque composition. Heart 2006;92:388- 391.
6. Yusuf S, Sleight P, Pogue J, Bosch J, Davies R, Dagenais G. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. New Engl J Med 2000;342:145-153.
7. Fox KM. Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study). Lancet 2003;362:782-788.
8. The CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS). New Engl J Med 1987;316: 1429-1435.
9. The SOLVD Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions, congestive heart failure. New Engl J Med 1991;325:293-302.
10. De Ciuceis C, Amiri F, Brassard P, Endemann DH, Touyz RM, Schiffrin EL. Reduced vascular remodeling, endothelial dysfunction, and oxidative stress in resistance arteries of angiotensin II-infused macrophage colony-stimulating factor-deficient mice: evidence for a role in inflammation in angiotensin-induced vascular injury. Arterioscler Thromb Vasc Biol 2005;25:2106-2113.
11. Dupuis F, Atkinson J, Liminana P, Chillon JM. Comparative effects of the angiotensin II receptor blocker, telmisartan, and the angiotensin-converting enzyme inhibitor, ramipril, on cerebrovascular structure in spontaneously hypertensive rats. J Hypertens 2005;23:1061-1066.
12. Ward MR, Pasterkamp G, Yeung AC, Borst C. Arterial remodeling. Mechanisms and clinical implications. Circulation 2000;102:1186-1191.
13. Hibi K, Ward MR, Honda Y, Suzuki T, Jeremias A, Okura H, Hassan AH, Maehara A, Yeung AC, Pasterkamp G, Fitzgerald PJ, Yock PG. Impact of different definitions on the interpretation of coronary remodeling determined by intravascular ultrasound. Catheter Cardiovasc Interv 2005;65:233- 239.
14. Rodriguez-Granillo GA, Agostoni P, Garcia-Garcia H, Biondi-Zoccai GGL, Mc Fadden E, Amoroso G, de Jaegere P, Bruining N, de Feyter P, Serruys PW. Meta-analysis of the studies assessing temporal changes in coronary plaque volume using intravascular ultrasound. Am J Cardiol 2007;99:5-10.
15. Rodriguez-Granillo GA, Bruining N, de Winter S, Vos J, Ligthart JM, Deckers J, Simoons ML, Fox K, de Feyter PJ. Long-term effect of perindopril on coronary atherosclerosis progression: results from the multicenter, randomized PERindopril's Prospective Effect on Coronary aTherosclerosis by angiography and IntraVascular ultrasound Evaluation (PERSPECTIVE) study, an EUROPA substudy. Am J Cardiol 2007 (in press).
16. De Winter SA, Hamers R, Degertekin M, Tanabe K, Lemos PA, Serruys PW, Roelandt JR, Bruining N. Retrospective image-based gating of intracoronary ultrasound images for improved quantitative analysis: the intelligate method. Catheter Cardiovasc Interv 2004;61:84-94.
17. Hausmann D, Lundkvist AJ, Friedrich GJ, Mullen WL, Fitzgerald PJ, Yock PG. Intracoronary ultrasound imaging: intraobserver and interobserver variability of morphometric measurements. Am Heart J 1994;128:674- 680.
18. de Winter SA, Heller I, Hamers R, de Feyter PJ, Serruys PWC, Roelandt JRTC, Bruining N. Computer assisted three-dimensional plaque characterization in ultracoronary ultrasound studies. Comput Cardiol 2003;30:73-76.
19. von Birgelen C, Klinkhart W, Mintz GS, Papatheodorou A, Herrmann J, Baumgart D, Haude M, Wieneke H, Ge J, Erbel R. Plaque distribution and vascular remodeling of ruptured and nonruptured coronary plaques in the same vessel: an intravascular ultrasound study in vivo. J Am Coll Cardiol 2001;37:1864-1870.
20. Smits PC, Pasterkamp G, Quarles van Ufford MA, Eefting FD, Stella PR, de Jaegere PP, Borst C. Coronary artery disease: arterial remodelling and clinical presentation. Heart 1999;82:461-464.
21. Sipahi I, Tuzcu EM, Schoenhagen P, Nicholls SJ, Ozduran V, Kapadia S, Nissen SE. Compensatory enlargement of human coronary arteries during progression of atherosclerosis is unrelated to atheroma burden: serial intravascular ultrasound observations from the REVERSAL trial. Eur Heart J 2006;27:1664-1670.
22. Schieffer B, Bunte C, Witte J, Hoeper K, Boger RH, Schwedhelm E, Drexler H. Comparative effects of AT1-antagonism and angiotensin-converting enzyme inhibition on markers of inflammation and platelet aggregation in patients with coronary artery disease. J Am Coll Cardiol 2004;44:362-368.
23. Schoenhagen P, Tuzcu EM, Apperson-Hansen C, Wang C, Wolski K, Lin S, Sipahi I, Nicholls SJ, Magyar WA, Loyd A, Churchill T, Crowe T, Nissen SE. Determinants of arterial wall remodeling during lipid-lowering therapy: serial intravascular ultrasound observations from the Reversal of Atherosclerosis with Aggressive Lipid Lowering Therapy (REVERSAL) trial. Circulation 2006;113:2826-2834.
24. Valgimigli M, Rodriguez-Granillo GA, Garcia-Garcia HM, Vaina S, De Jaegere P, de Feyter P, Serruys PW. Plaque composition in the left main stem mimics the distal but not the proximal tract of the left coronary artery: influence of clinical presentation, length of the left main trunk, lipid profile and systemic levels of C-reactive protein. J Am Coll Cardiol 2007;49:23-31.
25. Bruining N, Hamers R, Teo TJ, de Feijter PJ, Serruys PW, Roelandt JR. Adjustment method for mechanical Boston scientific corporation 30 MHz intravascular ultrasound catheters connected to a Clearview console Mechanical 30 MHz IVUS catheter adjustment. Int J Cardiovasc Imaging 2004;20:83-91.