Quantification of protein synthesis in the human brain using L-[1- 11C]-leucine PET: Incorporation of factors for large neutral amino acids in plasma and for amino acids recycled from tissue

Journal of Nuclear Medicine

Volumn 47, Issue 11, 2006, Pages 1787-1795

  Sundaram, Senthil K ^a   Muzik, Otto ^a,b   Chugani, Diane C ^a   Mu, Fanrong ^a   Mangner, Thomas J ^a   Chugani, Harry T ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHILDREN'S HOSPITAL OF MICHIGAN   (United States)

Author keywords

11C leucine; Brain protein synthesis; Compartmental modeling; Large neutral amino acids; Positron emission tomography

Indexed keywords

AMINO ACID; BRAIN PROTEIN; LEUCINE C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; CARBON; DIAGNOSTIC AGENT; LEUCINE; PROTEIN;

ADULT; AMINO ACID ANALYSIS; AMINO ACID BLOOD LEVEL; ARTERIAL BLOOD; ARTICLE; BLOOD SAMPLING; BRAIN; COMPARTMENT MODEL; CORRELATION ANALYSIS; DRUG UPTAKE; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN SYNTHESIS; QUANTITATIVE ANALYSIS; SEX DIFFERENCE; STATISTICAL SIGNIFICANCE; BLOOD; CHEMISTRY; KINETICS; METABOLISM; METHODOLOGY; MIDDLE AGED; PATHOLOGY;

ADULT; AMINO ACIDS, NEUTRAL; BRAIN; CARBON RADIOISOTOPES; FEMALE; HUMANS; KINETICS; LEUCINE; MALE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; PROTEIN BIOSYNTHESIS; PROTEINS; SEX FACTORS;

EID: 35148829059     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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