Alternative trial design in amyotrophic lateral sclerosis saves time and patients

Amyotrophic Lateral Sclerosis

Volumn 8, Issue 5, 2007, Pages 266-269

  Groeneveld, Geert Jan ^a   Graf, Michael ^b   Van der Tweel, Ingeborg ^c   Van den Berg, Leonard H ^a   Ludolph, Albert C ^d  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^c UTRECHT UNIVERSITY   (Netherlands)

^d UNIVERSITY OF ULM   (Germany)

Author keywords

Classical trial; Design; Randomized trial; Sequential trial design; Trial methodology

Indexed keywords

ALPHA TOCOPHEROL; PLACEBO; RILUZOLE;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CLINICAL RESEARCH; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; GERMANY; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; METHODOLOGY; OVERALL SURVIVAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE; SEQUENTIAL ANALYSIS; STATISTICAL MODEL; SURVIVAL RATE; TIME MANAGEMENT;

AMYOTROPHIC LATERAL SCLEROSIS; CLINICAL TRIALS AS TOPIC; CONFIDENCE INTERVALS; DOUBLE-BLIND METHOD; HUMANS; ODDS RATIO; RESEARCH DESIGN; RETROSPECTIVE STUDIES; SAMPLE SIZE; SURVIVAL ANALYSIS; TIME FACTORS; VITAMIN E;

EID: 35148828169     PISSN: 17482968     EISSN: 1471180X     Source Type: Journal    
DOI: 10.1080/17482960701419497     Document Type: Article

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