Evaluation of hardware in a small-animal SPECT system using reconstructed images

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 6515, Issue , 2007, Pages

  Hesterman, Jacob Y ^a   Kupinski, Matthew A ^a   Clarkson, Eric ^a   Wilson, Donald W ^a   Barrett, Harrison H ^a  

^a UNIVERSITY OF ARIZONA   (United States)

Author keywords

AUC; Differential point response function; Image quality, hardware evaluation; SPECT

Indexed keywords

DIFFERENTIAL POINT-RESPONSE FUNCTION; GAUSSIAN CHANNELS; HARDWARE EVALUATION; MULTI-PINHOLE APERTURES;

ANIMALS; COMPUTER HARDWARE; IMAGE QUALITY; IMAGING SYSTEMS; SYSTEMS ANALYSIS; THREE DIMENSIONAL;

IMAGE RECONSTRUCTION;

EID: 35148818792     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.709730     Document Type: Conference Paper

References (21)

1. S. R. Meikle, P. Kench, M. Kassiou, and R. B. Banati, "Small animal SPECT and its place in the matrix of molecular imaging technologies," Physics in Medicine and Biology 50, pp. R45-R61, 2005.
2. T. F. Massoud and S. S. Gambhir, "Molecular imaging in living subjects: seeing fundamental biological processes in a new light," Genes and Development 17, pp. 545-580, 2003.
3. N. Schramm, G. Ebel, U. Engeland, T. Schurrat, M. Behe, and T. Behr, "High-resolution SPECT using multipinhole collimation," IEEE Transactions on Nuclear Science 50(3), pp. 315-320, 2003.
4. F. J. Beekman, F. van der Have, B. Vastenhouw, A. J. van der Linden, P. P. van Rijk, J. P. H. Burbach, and M. P. Smith, "U-SPECT-I: A novel system for submillimeter-resolution tomography with radiolabeled molecules in mice," The Journal of Nuclear Medicine 46(7), pp. 1194-1200, 2005.
5. L. R. Furenlid, D. W. Wilson, Y. C. Chen, H. Kim, P. J. Pietraski, M. J. Crawford, and H. H. Barrett, "FastSPECT II: A second-generation high-resolution dynamic SPECT imager," IEEE Transactions on Nuclear Science 51(3), pp. 631-635, 2004.
6. T. Funk, P. Depres, W. C. Barber, K. S. Shah, and B. H. Hasegawa, "A multipinhole small animal SPECT system with submillimeter spatial resolution," Medical Physics 33(5), pp. 1259-1268, 2006.
7. R. Zimmerman, S. Moore, and A. Mahmood, "Performance of a triple-detector, multiple-pinhole SPECT system with iodine and indium isotopes," in Nuclear Science Symposium Conference Record, 2004 IEEE, 4, pp. 2427-2429, 2004.
8. B. Tsui, Y. Wang, B. Yoder, and E. Frey, "Micro-SPECT," in Biomedical Imaging, 2002. Proceedings, 2002 IEEE International Symposium on, pp. 373-376, 2002.
9. J. Hesterman, M. Kupinski, L. Furenlid, and D. Wilson, "Experimental task-based optimization of a four-camera variable-pinhole small-animal SPECT system," in Proceedings of SPIE, 5749, p. 300, 2005.
10. D. W. Wilson, Noise and resolution properties of FB and MLEM reconstructed SPECT images. PhD thesis, University of North Carolina at Chapel Hill, 1994.
11. H. H. Barrett and K. J. Myers, Foundations of Image Science, Wiley, Hoboken. New Jersey, 2004.
12. Y.-C. Chen, L. R. Furenlid, D. W. Wilson, and H. H. Barrett, Small-Animal SPECT Imaging, ch. 12, pp. 195-201. Springer, 2005.
13. J. Rolland and H. Barrett, "Effect of random background inhomogeneity on observer detection performance," Journal of the Optical Society of America A 9(5), pp. 649-658, 1992.
14. H. H. Barrett, "Objective assessment of image quality: effects of quantum noise and object variability," Journal of the Optical Society of America A, 1990.
15. B. D. Gallas, "One-Shot estimate of MRMC variance: AUC," Academic Radiology 13, pp. 353-362, 2006.
16. K. Fukunaga and R. R. Hayes, "Effects of sample size in classifier design," IEEE Transactions on Pattern Analysis and Machine Intelligence 11, pp. 873-885, August 1989.
17. K. J. Myers, Visual perception in correlated noise. PhD thesis, University of Arizona, 1985.
18. H. Barrett, C. Abbey, B. Gallas, and M. Eckstein, "Stabilized estimates of Hotelling-observer detection performance in patient-structured noise," Proceedings of SPIE 3340, pp. 27-43, 1998.
19. C. K. Abbey and H. H. Barrett, "Human- and model-observer performance in ramp-spectrum noise: effects of regularization and object variability," Journal of the Optical Society of America A 18, pp. 473-488, March 2001.
20. Correspondence with Dr. Yuchuan Wang of Johns Hopkins University.
21. K. Gross, Assessing and Optimizing Pinhole SPECT Imaging Systems for Detection Tasks. PhD thesis, University of Arizona, 2006.