Mucoadhesive bilayer tablets of propranolol hydrochloride

AAPS PharmSciTech

Volumn 8, Issue 3, 2007, Pages

  Patel, Vishnu M ^a,b   Prajapati, Bhupendra G ^b   Patel, Harsha V ^c   Patel, Karshanbhi M ^b  

^a APMC College of Pharmaceutical Education and Research   (India)

^b GANPAT UNIVERSITY   (India)

^c Indukaka Ipcowala College of Pharmacy   (India)

Author keywords

Bilayer device; Buccal drug delivery; Carbopol 934; Mucoadhesion; Propranolol hydrochloride; Sodium alginate

Indexed keywords

ALGINIC ACID; CARBOMER; ETHYL CELLULOSE; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIFFUSION; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG RELEASE; DRUG STABILITY; EX VIVO STUDY; FEMALE; IN VITRO STUDY; MALE; MOUTH CAVITY; NONHUMAN; PH MEASUREMENT; PROCESS OPTIMIZATION; RABBIT; SALIVA ANALYSIS; SUSTAINED DRUG RELEASE; TABLET DISINTEGRATION; TABLET FORMULATION; TABLET FRIABILITY; TABLET HARDNESS; TABLET SURFACE; TABLET THICKNESS; TACHYCARDIA; WEIGHT;

EID: 35148812297     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt0803051     Document Type: Article

References (22)

1. Gavini E, Sanna V, Juliano C, Bonferoni MC, Giunchedi P. Mucoadhesive vaginal tablets as veterinary delivery system for the controlled release of an antimicrobial drug, Acriflavine. AAPS PharmSciTech. 2002;3:Article 20.[serial online].
2. Harris D, Robinson JR. Drug delivery via the mucous membranes of the oral cavity. J Pharm Sci. 1992;81:1-10.
3. Ali J, Khar RK, Ahuja A. Formulation and characterization of a buccoadhesive erodible tablet for the treatment of oral lesions. Pharmazie. 1998;53:329-334.
4. Kohda Y, Kobayashi H, Baba Y, et al. Controlled release of lidocaine hydrochloride from buccal mucosa-adhesive films with solid dispersion. Int J Pharm. 1983;15:147-155.
5. Nair MK, Chien YW. Development of anticandidal delivery systems. II. mucoadhesive devices for prolonged drug delivery in the oral cavity. Drug Dev Ind Pharm. 1996;22:243-253.
6. Parodi B, Russo E, Caviglioli G, Cafaggi S, Bignardi G. Development and characterization of a buccoadhesive dosage form of oxycodone hydrochloride. Drug Dev Ind Pharm. 1996;22:445-450.
7. Shin SC, Bum JP, Choi JS. Enhanced bioavailability by buccal administration of triamcinolone acetonide from the bioadhesive gels in rabbits. Int J Pharm. 2000;209:37-43.
8. Nagai T, Konishi R. Buccal/gingival drug delivery systems. J Control Release. 1987;6:353-360.
9. Cid E, Mella F, Lucchini L, Carcamo M, Monasterio J. Plasma concentrations and bioavailability of propranolol by oral, rectal and intravenous administration in man. Biopharm Drug Dispos. 1986;7:559-566.
10. Walle T, Conradi EC, Walle UK, Fagan TC, Gaffney TE. The predictable relationship between plasma levels and dose during chronic propranolol therapy. Clin Pharmacol Ther. 1978;24:668-677.
11. Kemken J, Ziegler A, Muller BW. Pharmacodynamic effects of transdermal bupranolol and timolol in vivo: comparison of micro emulsions and matrix patches as vehicle. Methods Find Exp Clin Pharmacol. 1991;13:361-365.
12. Gupta A, Garg S, Khar RK. Measurement of bioadhesive strength of muco-adhesive buccal tablets: design of an in-vitro assembly. Indian Drugs. 1992;30:152-155.
13. Bottenberg P, Cleymaet R, Muynek CD, Remon JP, Coomans D, Slop D. Development and testing of bioadhesive, fluoride-containing slow-release tablets for oral use. J Pharm Pharmacol. 1991;43:457-464.
14. Kemken J, Ziegler A, Muller BW. Investigation into the pharmacodynamic effects of dermally administered microemulsions containing beta-blockers. J Pharm Pharmacol. 1991;43:679-684.
15. De Vries ME, Bodde HE, Verhoef JC, Junginger HE. Developments in buccal drug delivery. Crit Rev Ther Drug Carrier Syst. 1991;8: 271-303.
16. Chidambaram N, Srivatsava AK. Buccal drug delivery systems. Drug Dev Ind Pharm. 1995;21:1009-1036.
17. Duchene D, Touchard F, Pappas NA. Pharmaceutical and medical aspects of bioadhesive systems for drug administration. Drug Dev Ind Pharm. 1988;14:283-318.
18. Guo JH, Cooklock M. The effect of backing materials and multilayered systems on the characteristics of bioadhesive buccal patches. J Pharm Pharmacol. 1996;48:255-257.
19. Peppas NA, Bury PA. Surface interfacial and molecular aspects of polymer bioadhesion on soft tissues. J Control Release. 1985;2:257-275.
20. Ilango R, Kavimani S, Mullaicharam AR, Jayakar B. In vitro studies on buccal strips of glibenclamide using chitosan. Indian J Pharm Sci. 1997;59:232-235.
21. Agarwal V, Mishra B. Design, development, and biopharmaceutical properties of buccoadhesive compacts of omeprazole. Drug Dev Ind Pharm. 1999;25:701-709.
22. Peppas NA. Analysis of Fickian and non-Fickian drug release from polymers. Pharm Acta Helv. 1985;60:110-111.