Optimal fed-batch cultivation when mass transfer becomes limiting

Biotechnology and Bioengineering

Volumn 98, Issue 3, 2007, Pages 706-710

  Villadsen, John ^a   Patil, Kiran R ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Aerobic fed batch; Avoiding stress responses; Exponential versus constant feed rate; Minimizing total cultivation time; Oxygen limitation

Indexed keywords

BIOMASS; DRUG PRODUCTS; GLUCOSE; MASS TRANSFER; OXYGEN; PROTEINS;

AEROBIC FED BATCH; AVOIDING STRESS RESPONSES; EXPONENTIAL VERSUS CONSTANT FEED RATE; MINIMIZING TOTAL CULTIVATION TIME; OXYGEN LIMITATION;

BIOMEDICAL ENGINEERING;

ENDOTOXIN; GLUCOSE;

ARTICLE; BIOMASS; CARBON SOURCE; CONCENTRATION (PARAMETERS); FED BATCH CULTURE; STRESS;

BACTERIA, AEROBIC; BIOREACTORS; CELL CULTURE TECHNIQUES; CELL SURVIVAL; COMPUTER SIMULATION; GLUCOSE; MODELS, BIOLOGICAL; OXYGEN;

EID: 35048889542     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21451     Document Type: Article

References (3)

1. Nielsen J, Villadsen J, Lidén G. 2002. Bioreaction engineering principles, 2nd edition. New York: Kluwer Academic/Plenum Publishers (Now: Springer Verlag).
2. Svensson M. 2006. The temperature-limited fed-batch technique for control of Escherichia coli cultures. PhD thesis KTH (Stockholm).
3. Svensson M, Han Silfversparre G, Häggström L, Enfors SO. 2005. Control of endotoxin release in Escherichia coli fed batch cultures. Bioprocess Biosyst Eng 27:91-97.