The study of vascular smooth muscle cells proliferation stimulated by Apelin-13

Chinese Pharmacological Bulletin

Volumn 23, Issue 7, 2007, Pages

  Li, Feng ^a   Li, Lan Fang ^a   Qin, Xu Ping ^a   Pan, Wei Nan ^a   Feng, Fen ^a   Chen, Feng ^a   Zhu, Bing Yang ^a   Liao, Duan Fang ^a   Chen, Lin Xi ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Apelin; APJ; Cyclin D1; Vascular smooth muscle cells

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; APELIN 13; CHINESE DRUG; CYCLIN D1; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STIMULATION; CLINICAL STUDY; CONTROLLED STUDY; DRUG EFFECT; FLOW CYTOMETRY; NONHUMAN; PROTEIN EXPRESSION; RAT; THORACIC AORTA; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

EID: 35048877864     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. O'Dowd B F, Heiber M, Chan A, et al. A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11 [J]. Gene,1993,136(1-2):355-60.
2. Tatemoto K, Hosoya M, Habata Y, et al. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor[J]. Biochem Biophys Res Commun,1998,251:471-6.
3. Hosoya M, Kawamata Y, Fukusumi S, et al. Molecular and functional characteristics of APJ. Tissue distribution of mRNA and interaction with the endogenous ligand Apelin [J]. J Biol Chem, 2000,275:21061-7.
4. Masri B, Knibiehler B, Audigier Y. Apelin signalling: a promising pathway from cloning to pharmacology [J]. Cellular Signalling, 2005,174:415-26.
5. Kasai A, Shintani N, Oda M, et al. Apelin is a novel angiogenic factor in retinal endothelial cells [J]. Biochem Biophys Res Commun,2004, 325(2):395-400.
6. Xie H, Tang S Y, Cui R R, et al. Apelin and its receptor are expressed in human osteoblasts[J]. Regul Pept,2006,134(2-3):118-25.
7. (125)I]-(Pyr(1) Apelin-13 is a novel radioligand for localizing the APJ orphan receptor in human and rat tissues with evidence for a vasoconstrictor role in man[J]. Br J Pharmacol,2001,132(6):1255-60.
8. Kleinz M J, Davenport A P. Immunocytochemical localization of the endogenous vasoactive peptide Apelin to human vascular and endocardial endothelial cells [J]. Regulatory peptides,2004,118(3):119-25.
9. Kleinz M J, Skepper J N, Davenport A P. Immunocytochemical localisation of the Apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells[J]. Regulatory peptides,2005,126(3):233-40.
10. Zhang X Y, Liu Y H, Liao D F, et al. Effect of Losartan and CGRP on the proliferation of vascular smooth muscle cell induced by angiotensin II [J]. Chin Pharmacol Bull,2006,22(1):101-5.
11. Cheng X, Cheng X S, Pang C C. Venous dilator effect of Apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats[J]. Eur J Pharmacol,2003,470(3):171-5.
12. Ishida J, Hashimoto T, Hashimoto Y, et al. Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo [J]. J Biol Chem,2004,279(25):26274-9.
13. Hashimoto T, Kihara M, Ishida J, et al. Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells[J]. Arterioscler Thromb Vasc Biol,2006,26(6):1267-72.
14. Chen M M, Ashley E A, Deng D X, et al. Novel role for the potent endogenous inotrope Apelin in human cardiac dysfunction[J]. Circulation, 2003,108(12):1432-9.