Engineering a selective small-molecule substrate binding site into a deoxyribozyme

Angewandte Chemie - International Edition

Volumn 46, Issue 39, 2007, Pages 7420-7424

  Höbartner, Claudia ^a   Silverman, Scott K ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Deoxyribozymes; Hydrogen bonds; Nucleic acids; Receptors; RNA recognition

Indexed keywords

ENZYMES; HYDROGEN BONDS; NUCLEIC ACIDS; SUBSTRATES;

DEOXYRIBOZYMES; RECEPTORS; RNA RECOGNITION;

MOLECULAR STRUCTURE;

DEOXYRIBOZYME; PURINE NUCLEOTIDE; PYRIMIDINE NUCLEOTIDE;

ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; METABOLISM;

BINDING SITES; CATALYSIS; CYTOSINE NUCLEOTIDES; DNA, CATALYTIC; MOLECULAR STRUCTURE; PURINE NUCLEOTIDES; SUBSTRATE SPECIFICITY;

EID: 35048862889     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200702217     Document Type: Article

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16. See the Supporting Information for all data that is not shown in the figures.
17. [9] and a similar trend is observed with 10DM24 (see the Supporting Information).
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