메뉴 건너뛰기




Volumn 80, Issue 4, 2007, Pages 279-285

Beta-2-adrenergic receptor polymorphisms and changes in lipids induced by metoprolol

Author keywords

2 receptor; Adrenoceptors; Polymorphism

Indexed keywords

ANTILIPEMIC AGENT; ARGININE; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; GLUTAMINE; GLYCINE; LIPID; METOPROLOL;

EID: 35048860060     PISSN: 00317012     EISSN: None     Source Type: Journal    
DOI: 10.1159/000106554     Document Type: Article
Times cited : (12)

References (49)
  • 2
    • 0023194433 scopus 로고
    • Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions
    • Kobilka BK, Frielle T, Dohlman HG, Bolanowski MA, Dixon RA, Keller P, Caron MG, Lefkowitz RJ: Delineation of the intronless nature of the genes for the human and hamster beta 2-adrenergic receptor and their putative promoter regions. J Biol Chem 1987;262:7321-7327.
    • (1987) J Biol Chem , vol.262 , pp. 7321-7327
    • Kobilka, B.K.1    Frielle, T.2    Dohlman, H.G.3    Bolanowski, M.A.4    Dixon, R.A.5    Keller, P.6    Caron, M.G.7    Lefkowitz, R.J.8
  • 3
    • 0034108680 scopus 로고    scopus 로고
    • Beta(2)-adrenergic receptor pharmacogenetics
    • Liggett SB: Beta(2)-adrenergic receptor pharmacogenetics. Am J Respir Crit Care Med 2000;161:S197-S201.
    • (2000) Am J Respir Crit Care Med , vol.161
    • Liggett, S.B.1
  • 4
    • 0035090301 scopus 로고    scopus 로고
    • Association analysis of beta(2)-adrenergic receptor polymorphisms with hypertension in Japanese
    • Kato N, Sugiyama T, Morita H, Kurihara H, Sato T, Yamori Y, Yazaki Y: Association analysis of beta(2)-adrenergic receptor polymorphisms with hypertension in Japanese. Hypertension 2001;37:286-292.
    • (2001) Hypertension , vol.37 , pp. 286-292
    • Kato, N.1    Sugiyama, T.2    Morita, H.3    Kurihara, H.4    Sato, T.5    Yamori, Y.6    Yazaki, Y.7
  • 6
  • 7
    • 0042868378 scopus 로고    scopus 로고
    • Beta-adrenoceptor genotype influences the response to carvedilol in patients with congestive heart failure
    • Kaye DM, Smirk B, Williams C, Jennings G, Esler M, Holst D: Beta-adrenoceptor genotype influences the response to carvedilol in patients with congestive heart failure. Pharmacogenetics 2003;13:379-382.
    • (2003) Pharmacogenetics , vol.13 , pp. 379-382
    • Kaye, D.M.1    Smirk, B.2    Williams, C.3    Jennings, G.4    Esler, M.5    Holst, D.6
  • 9
    • 8144221767 scopus 로고    scopus 로고
    • Interaction between cardiac sympathetic drive and heart rate in heart failure: Modulation by adrenergic receptor genotype
    • Kaye DM, Smirk B, Finch S, Williams C, Esler MD: Interaction between cardiac sympathetic drive and heart rate in heart failure: modulation by adrenergic receptor genotype. J Am Coll Cardiol 2004;44:2008-2015.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 2008-2015
    • Kaye, D.M.1    Smirk, B.2    Finch, S.3    Williams, C.4    Esler, M.D.5
  • 13
    • 3242713280 scopus 로고    scopus 로고
    • Beta 2-adrenergic receptor polymorphisms and haplotypes are associated with airways hyperresponsiveness among nonsmoking men
    • Litonjua AA, Silverman EK, Tantisira KG, Sparrow D, Sylvia JS, Weiss ST: Beta 2-adrenergic receptor polymorphisms and haplotypes are associated with airways hyperresponsiveness among nonsmoking men. Chest 2004;126:66-74.
    • (2004) Chest , vol.126 , pp. 66-74
    • Litonjua, A.A.1    Silverman, E.K.2    Tantisira, K.G.3    Sparrow, D.4    Sylvia, J.S.5    Weiss, S.T.6
  • 15
    • 3242759712 scopus 로고    scopus 로고
    • Le Souef PN: Beta2 adrenoceptor Arg16Gly polymorphism, airway responsiveness, lung function and asthma in infants and children
    • Turner SW, Khoo SK, Laing IA, Palmer LJ, Gibson NA, Rye P, Landau LI, Goldblatt J, Le Souef PN: beta2 adrenoceptor Arg16Gly polymorphism, airway responsiveness, lung function and asthma in infants and children. Clin Exp Allergy 2004;34:1043-1048.
    • (2004) Clin Exp Allergy , vol.34 , pp. 1043-1048
    • Turner, S.W.1    Khoo, S.K.2    Laing, I.A.3    Palmer, L.J.4    Gibson, N.A.5    Rye, P.6    Landau, L.I.7    Goldblatt, J.8
  • 16
    • 33747797059 scopus 로고    scopus 로고
    • Beta2-adrenoreceptor polymorphisms and asthma
    • Wjst M: Beta2-adrenoreceptor polymorphisms and asthma. Lancet 2006;368:710-711.
    • (2006) Lancet , vol.368 , pp. 710-711
    • Wjst, M.1
  • 17
    • 0242269451 scopus 로고    scopus 로고
    • The Gly16-> Arg16 and Gln27->Glu27 polymorphisms of beta2-adrenergic receptor are associated with metabolic syndrome in men
    • Dallongeville J, Helbecque N, Cottel D, Amouyel P, Meirhaeghe A: The Gly16-> Arg16 and Gln27->Glu27 polymorphisms of beta2-adrenergic receptor are associated with metabolic syndrome in men. J Clin Endocrinol Metab 2003;88:4862-4866.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4862-4866
    • Dallongeville, J.1    Helbecque, N.2    Cottel, D.3    Amouyel, P.4    Meirhaeghe, A.5
  • 18
    • 0033923680 scopus 로고    scopus 로고
    • The Q/E27 polymorphism in the beta2-adrenoceptor gene is associated with increased body weight and dyslipoproteinaemia involving triglyceride-rich lipoproteins
    • Ehrenborg E, Skogsberg J, Ruotolo G, Large V, Eriksson P, Arner P, Hamsten A: The Q/E27 polymorphism in the beta2-adrenoceptor gene is associated with increased body weight and dyslipoproteinaemia involving triglyceride-rich lipoproteins. J Intern Med 2000;247:651-656.
    • (2000) J Intern Med , vol.247 , pp. 651-656
    • Ehrenborg, E.1    Skogsberg, J.2    Ruotolo, G.3    Large, V.4    Eriksson, P.5    Arner, P.6    Hamsten, A.7
  • 19
    • 0031436966 scopus 로고    scopus 로고
    • Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function
    • Large V, Hellstrom L, Reynisdottir S, Lonnqvist F, Eriksson P, Lannfelt L, Arner P: Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function. J Clin Invest 1997;100:3005-3013.
    • (1997) J Clin Invest , vol.100 , pp. 3005-3013
    • Large, V.1    Hellstrom, L.2    Reynisdottir, S.3    Lonnqvist, F.4    Eriksson, P.5    Lannfelt, L.6    Arner, P.7
  • 20
    • 33749353201 scopus 로고    scopus 로고
    • Beta2-adrenoceptor polymorphisms relate to obesity through blunted leptin-mediated sympathetic activation
    • Masuo K, Katsuya T, Kawaguchi H, Fu Y, Rakugi H, Ogihara T, Tuck ML: Beta2-adrenoceptor polymorphisms relate to obesity through blunted leptin-mediated sympathetic activation. Am J Hypertens 2006;19:1084-1091.
    • (2006) Am J Hypertens , vol.19 , pp. 1084-1091
    • Masuo, K.1    Katsuya, T.2    Kawaguchi, H.3    Fu, Y.4    Rakugi, H.5    Ogihara, T.6    Tuck, M.L.7
  • 21
    • 33846100236 scopus 로고    scopus 로고
    • Wessel J, Moratorio G, Rao F, Mahata M, Zhang L, Greene W, Rana BK, Kennedy BP, Khandrika S, Huang P, Lillie EO, Shih PA, Smith DW, Wen G, Hamilton BA, Ziegler MG, Witztum JL, Schork NJ, Schmid-Schonbein GW, O'Connor DT: C-reactive protein, an 'intermediate phenotype' for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/beta- adrenergic pathway loci. J Hypertens 2007;25:329-343.
    • Wessel J, Moratorio G, Rao F, Mahata M, Zhang L, Greene W, Rana BK, Kennedy BP, Khandrika S, Huang P, Lillie EO, Shih PA, Smith DW, Wen G, Hamilton BA, Ziegler MG, Witztum JL, Schork NJ, Schmid-Schonbein GW, O'Connor DT: C-reactive protein, an 'intermediate phenotype' for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/beta- adrenergic pathway loci. J Hypertens 2007;25:329-343.
  • 22
    • 0034125622 scopus 로고    scopus 로고
    • Influence of genetic polymorphisms in the beta2-adrenoceptor on desensitization in human lung mast cells
    • Chong LK, Chowdry J, Ghahramani P, Peachell PT: Influence of genetic polymorphisms in the beta2-adrenoceptor on desensitization in human lung mast cells. Pharmacogenetics 2000;10:153-162.
    • (2000) Pharmacogenetics , vol.10 , pp. 153-162
    • Chong, L.K.1    Chowdry, J.2    Ghahramani, P.3    Peachell, P.T.4
  • 23
    • 0035807591 scopus 로고    scopus 로고
    • The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization
    • Dishy V, Sofowora GG, Xie HG, Kim RB, Byrne DW, Stein CM, Wood AJ: The effect of common polymorphisms of the beta2-adrenergic receptor on agonist-mediated vascular desensitization. N Engl J Med 2001;345:1030-1035.
    • (2001) N Engl J Med , vol.345 , pp. 1030-1035
    • Dishy, V.1    Sofowora, G.G.2    Xie, H.G.3    Kim, R.B.4    Byrne, D.W.5    Stein, C.M.6    Wood, A.J.7
  • 25
    • 0033621973 scopus 로고    scopus 로고
    • beta2-adrenergic receptor polymorphisms at amino acid 16 differentially influence agonist-stimulated blood pressure and peripheral blood flow in normal individuals
    • Hoit BD, Suresh DP, Craft L, Walsh RA, Liggett SB: beta2-adrenergic receptor polymorphisms at amino acid 16 differentially influence agonist-stimulated blood pressure and peripheral blood flow in normal individuals. Am Heart J 2000;139:537-542.
    • (2000) Am Heart J , vol.139 , pp. 537-542
    • Hoit, B.D.1    Suresh, D.P.2    Craft, L.3    Walsh, R.A.4    Liggett, S.B.5
  • 28
    • 1642544641 scopus 로고    scopus 로고
    • Beta2-adrenoceptor polymorphisms: Relation between in vitro and in vivo phenotypes
    • Leineweber K, Brodde OE: Beta2-adrenoceptor polymorphisms: relation between in vitro and in vivo phenotypes. Life Sci 2004;74:2803-2814.
    • (2004) Life Sci , vol.74 , pp. 2803-2814
    • Leineweber, K.1    Brodde, O.E.2
  • 31
    • 0034032303 scopus 로고    scopus 로고
    • Obesity - a genetic disease of adipose tissue?
    • Arner P: Obesity - a genetic disease of adipose tissue? Br J Nutr 2000;83(suppl 1):S9-S16.
    • (2000) Br J Nutr , vol.83 , Issue.SUPPL. 1
    • Arner, P.1
  • 32
    • 0034744185 scopus 로고    scopus 로고
    • Common variants in the beta2-(Gln27Glu) and beta3-(Trp64Arg)-adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes
    • Carlsson M, Orho-Melander M, Hedenbro J, Groop LC: Common variants in the beta2-(Gln27Glu) and beta3-(Trp64Arg)-adrenoceptor genes are associated with elevated serum NEFA concentrations and type II diabetes. Diabetologia 2001;44:629-636.
    • (2001) Diabetologia , vol.44 , pp. 629-636
    • Carlsson, M.1    Orho-Melander, M.2    Hedenbro, J.3    Groop, L.C.4
  • 33
    • 33846786457 scopus 로고    scopus 로고
    • Studies of the associations between functional beta(2)-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects
    • Gjesing AP, Andersen G, Burgdorf KS, Borch-Johnsen K, Jorgensen T, Hansen T, Pedersen O: Studies of the associations between functional beta(2)-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects. Diabetologia 2007;50:563-568.
    • (2007) Diabetologia , vol.50 , pp. 563-568
    • Gjesing, A.P.1    Andersen, G.2    Burgdorf, K.S.3    Borch-Johnsen, K.4    Jorgensen, T.5    Hansen, T.6    Pedersen, O.7
  • 34
    • 0033624581 scopus 로고    scopus 로고
    • Polymorphisms of the beta2-adrenergic receptor gene (ADRB2) in relation to cardiovascular risk factors in men
    • Rosmond R, Ukkola O, Chagnon M, Bouchard C, Bjorntorp P: Polymorphisms of the beta2-adrenergic receptor gene (ADRB2) in relation to cardiovascular risk factors in men. J Intern Med 2000;248:239-244.
    • (2000) J Intern Med , vol.248 , pp. 239-244
    • Rosmond, R.1    Ukkola, O.2    Chagnon, M.3    Bouchard, C.4    Bjorntorp, P.5
  • 35
    • 0035167532 scopus 로고    scopus 로고
    • Beta-2 adrenergic receptor variants are associated with subcutaneous fat accumulation in response to long-term overfeeding
    • Ukkola O, Tremblay A, Bouchard C: Beta-2 adrenergic receptor variants are associated with subcutaneous fat accumulation in response to long-term overfeeding. Int J Obes Relat Metab Disord 2001;25:1604-1608.
    • (2001) Int J Obes Relat Metab Disord , vol.25 , pp. 1604-1608
    • Ukkola, O.1    Tremblay, A.2    Bouchard, C.3
  • 36
    • 33645106319 scopus 로고    scopus 로고
    • New treatment strategies for patients with hypertension and insulin resistance
    • Kurtz TW: New treatment strategies for patients with hypertension and insulin resistance. Am J Med 2006;119:S24-S30.
    • (2006) Am J Med , vol.119
    • Kurtz, T.W.1
  • 37
    • 27144503123 scopus 로고    scopus 로고
    • Di Renzo G: Beta-Blockade and increased dyslipidemia in patients bearing Glu27 variant of beta2 adrenergic receptor gene
    • Iaccarino G, Trimarco V, Lanni F, Cipolletta E, Izzo R, Arcucci O, De Luca N, Di Renzo G: beta-Blockade and increased dyslipidemia in patients bearing Glu27 variant of beta2 adrenergic receptor gene. Pharmacogenomics J 2005;5:292-297.
    • (2005) Pharmacogenomics J , vol.5 , pp. 292-297
    • Iaccarino, G.1    Trimarco, V.2    Lanni, F.3    Cipolletta, E.4    Izzo, R.5    Arcucci, O.6    De Luca, N.7
  • 38
    • 18744402754 scopus 로고    scopus 로고
    • Polymorphic variants of the beta2-adrenergic receptor (ADRB2) gene and ADRB2-related propanolol-induced dyslipidemia in the Colombian population
    • Isaza C, Henao J, Ramirez E, Cuesta F, Cacabelos R: Polymorphic variants of the beta2-adrenergic receptor (ADRB2) gene and ADRB2-related propanolol-induced dyslipidemia in the Colombian population. Methods Find Exp Clin Pharmacol 2005;27:237-244.
    • (2005) Methods Find Exp Clin Pharmacol , vol.27 , pp. 237-244
    • Isaza, C.1    Henao, J.2    Ramirez, E.3    Cuesta, F.4    Cacabelos, R.5
  • 39
    • 2342443107 scopus 로고    scopus 로고
    • Rapid identification of single nucleotide polymorphisms by fluorescence-based capillary electrophoresis
    • Bernat M, Titos E, Claria J: Rapid identification of single nucleotide polymorphisms by fluorescence-based capillary electrophoresis. Genet Mol Res 2002;1:72-78.
    • (2002) Genet Mol Res , vol.1 , pp. 72-78
    • Bernat, M.1    Titos, E.2    Claria, J.3
  • 40
    • 0034896764 scopus 로고    scopus 로고
    • Identification of N-acetyltransferase 2 and CYP2C19 genotypes for hair, buccal cell swabs, or fingernails compared with blood
    • Tanigawara Y, Kita T, Hirono M, Sakaeda T, Komada F, Okumura K: Identification of N-acetyltransferase 2 and CYP2C19 genotypes for hair, buccal cell swabs, or fingernails compared with blood. Ther Drug Monit 2001;23:341-346.
    • (2001) Ther Drug Monit , vol.23 , pp. 341-346
    • Tanigawara, Y.1    Kita, T.2    Hirono, M.3    Sakaeda, T.4    Komada, F.5    Okumura, K.6
  • 42
    • 0345730916 scopus 로고    scopus 로고
    • Genotype Gly/Gly of the Arg16Gly polymorphism of the beta2-adrenergic receptor is associated with elevated fasting serum insulin concentrations, but not with acute insulin response to glucose, in type 2 diabetic patients
    • Ikarashi T, Hanyu O, Maruyama S, Souda S, Kobayashi C, Abe E, Ukisu J, Naganuma K, Suzuki A, Toya M, Kaneko S, Suzuki K, Nakagawa O, Aizawa Y: Genotype Gly/Gly of the Arg16Gly polymorphism of the beta2-adrenergic receptor is associated with elevated fasting serum insulin concentrations, but not with acute insulin response to glucose, in type 2 diabetic patients. Diabetes Res Clin Pract 2004;63:11-18.
    • (2004) Diabetes Res Clin Pract , vol.63 , pp. 11-18
    • Ikarashi, T.1    Hanyu, O.2    Maruyama, S.3    Souda, S.4    Kobayashi, C.5    Abe, E.6    Ukisu, J.7    Naganuma, K.8    Suzuki, A.9    Toya, M.10    Kaneko, S.11    Suzuki, K.12    Nakagawa, O.13    Aizawa, Y.14
  • 44
    • 3342881024 scopus 로고    scopus 로고
    • Obesity studies in candidate genes (in Spanish)
    • Ochoa Mdel C, Marti A, Martinez JA: Obesity studies in candidate genes (in Spanish). Med Clin (Barc) 2004;122:542-551.
    • (2004) Med Clin (Barc) , vol.122 , pp. 542-551
    • Ochoa Mdel, C.1    Marti, A.2    Martinez, J.A.3
  • 45
    • 0032965116 scopus 로고    scopus 로고
    • Beta-blocker effects on plasma lipids during prolonged treatment of hypertensive patients with hypercholesterolemia
    • Fogari R, Zoppi A, Corradi L, Preti P, Mugellini A, Lusardi P: Beta-blocker effects on plasma lipids during prolonged treatment of hypertensive patients with hypercholesterolemia. J Cardiovasc Pharmacol 1999;33:534-539.
    • (1999) J Cardiovasc Pharmacol , vol.33 , pp. 534-539
    • Fogari, R.1    Zoppi, A.2    Corradi, L.3    Preti, P.4    Mugellini, A.5    Lusardi, P.6
  • 46
    • 0033970797 scopus 로고    scopus 로고
    • Diuretics and beta-blockers: Is there a risk for dyslipidemia?
    • Weir MR, Moser M: Diuretics and beta-blockers: is there a risk for dyslipidemia? Am Heart J 2000;139:174-183.
    • (2000) Am Heart J , vol.139 , pp. 174-183
    • Weir, M.R.1    Moser, M.2
  • 49
    • 0036682101 scopus 로고    scopus 로고
    • Single nucleotide polymorphism seeking long term association with complex disease
    • Kirk BW, Feinsod M, Favis R, Kliman RM, Barany F: Single nucleotide polymorphism seeking long term association with complex disease. Nucleic Acids Res 2002;30:3295-3311.
    • (2002) Nucleic Acids Res , vol.30 , pp. 3295-3311
    • Kirk, B.W.1    Feinsod, M.2    Favis, R.3    Kliman, R.M.4    Barany, F.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.