Research into putative biological mechanisms of mental disorders has been of no value to clinical psychiatry

British Journal of Psychiatry

Volumn 191, Issue OCT., 2007, Pages 285-290

  Kingdon, David ^a   Young, Allan H ^b  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; CHLORPROMAZINE; CLOZAPINE; CORTICOSTEROID; LITHIUM;

ALZHEIMER DISEASE; ANXIETY; BIPOLAR DISORDER; CHROMATOGRAPHY; DEPRESSION; DEXAMETHASONE SUPPRESSION TEST; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MENTAL DISEASE; NEUROIMAGING; PSYCHOSIS; REVIEW; SCHIZOPHRENIA;

BIOLOGICAL PSYCHIATRY; MENTAL DISORDERS; PERSONALITY; RESEARCH; STEREOTYPING;

EID: 35048836141     PISSN: 00071250     EISSN: None     Source Type: Journal    
DOI: 10.1192/bjp.bp.107.035675     Document Type: Review

References (31)

1. Angermeyer, M. C. & Matschinger, H. (2005) Causal beliefs and attitudes to people with schizophrenia. Trend analysis based on data from two population surveys in Germany. British Journal of Psychiatry, 186, 331-334.
2. Baldessarini, R., Tondo, L., Davis, P., et al (2006) Decreased risk of suicides and attempts during lithium treatment: a meta-analytic review. Bipolar disorders, 8, 625-639.
3. Bauer, M., Adli, M., Baethge, C., et al (2003) Lithium augmentation in refractory depression: clinical evidence and neurobiological mechanisms. Canadian Journal of Psychiatry, 48, 440-448.
4. Bentall, R. P. (2004) Madness Explained: Psychosis and Human Nature. Penguin Books.
5. Cade, J. F. (1975) Lithium - when, why and how? Medical Journal of Australia, 1 (22), 684-686.
6. Craddock, N. & Owen, M. J. (2005) The beginning of the end for the Kraepelinian dichotomy. British Journal of Psychiatry, 186, 364-366.
7. Cunningham Owens, D. G., Carroll, A., Fattah, S., et al (2001) A randomized, controlled trial of a brief interventional package for schizophrenic out-patients. Acta Psychiatrica Scandinavica, 103, 362-369.
8. Gartside, S. E., Leitch, M. M. & Young, A. H. (2003) Altered glucocorticoid rhythm attenuates the ability of a chronic SSRI to elevate forebrain 5-HT: implications for the treatment of depression. Neuropsychopharmacology, 28, 1572-1578.
9. Geddes, J. R., Burgess, S., Hawton, K., et al (2004) Long term lithium therapy for bipolar disorder: systematic review and meta-analysis of randomized controlled trials. American Journal of Psychiatry 161, 217-222.
10. Guze, S. B. (1989) Biological psychiatry: is there any other kind? Psychological Medicine, 19, 315-323.
11. Hall, W. (2006) Is cannabis use psychotogenic? Lancet, 367, 193-195.
12. Kane, J., Honigfeld, G., Singer, J., et al (1988) Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. Archives of General Psychiatry, 45, 789-796.
13. Kendell, R. E. (1975) The Role of Diagnosis in Psychiatry. Blackwell.
14. Kendell, R. E. (2001) The distinction between mental and physical illness. British Journal of Psychiatry, 178, 490-493.
15. Kendell, R. E. & Zeally, A. K. (1988) Companion to Psychiatric Studies. Churchill Livingstone.
16. Kingdon, D. (2006a) Health research funding: mental health research continues to be underfunded. BMJ, 332, 1510.
17. Kingdon, D. (2006b) Psychological and social interventions for schizophrenia. BMJ, 333, 212-213.
18. Kingdon, D. G. & Turkington, D. (2005) Cognitive Therapy of Schizophrenia. Guilford.
19. Kingdon, D., Sharma, T. & Hart, D. (2004) What attitudes do psychiatrists hold towards people with mental illness? Psychiatric Bulletin, 28, 401-406.
20. Kingdon, D., Gibson, A., Turkington, D., et al (2007) Acceptable terminology and subgroups in schizophrenia: an exploratory study. Social Psychiatry and Psychiatric Epidemiology, in press.
21. Kunugi, H., Ida, I., Owashi, T., et al (2006) Assessment of the dexamethasone/CRH test as a state-dependent marker for hypothalamic-pituitary-adrenal (HPA) axis abnormalities in major depressive episode: a multicenter study. Neuropsychopharmacology, 31, 212-220.
22. Lopez-Munoz, F., Alamo, C., Cuenca, E., et al (2005) History of the discovery and clinical introduction of chlorpromazine. Annals of Clinical Psychiatry, 17, 113-135.
23. Meaney, M. J. & Szyf, M. (2005) Maternal care as a model for experience-dependent chromatin plasticity? Trends in Neurosciences, 28, 456-463.
24. Myin-Germeys, I., Delespaul, P. & Van, O. J. (2005) Behavioral sensitization to daily life stress in psychosis. Psychological Medicine, 35, 733-741.
25. Nitrini, R. (2005) The cure of one of the most frequent types of dementia: a historical parallel. Alzheimer Disease and Associated Disorders, 19, 156-158.
26. Rathod, S., Kingdon, D., Smith, P., et al (2005) Insight into schizophrenia: the effects of cognitive behavioural therapy on the components of insight and association with sociodemographics - data on a previously published randomised controlled trial. Schizophrenia Research, 74, 211-219.
27. Read, J., Agar, K., Argyle, N., et al (2003) Sexual and physical abuse during childhood and adulthood as predictors of hallucinations, delusions and thought disorder. Psychology and Psychotherapy, 76, 1-22.
28. Teskey, P. (2006) What's in a name? A case for changing the 'S' word. Schizophrenia Digest, 4, 36-37.
29. Watson, S., Gallagher, P., Ritchie, J. C., et al (2004) Hypothalamic-pituitary-adrenal axis function in patients with bipolar disorder. British Journal of Psychiatry, 184, 496-502.
30. Watson, S., Gallagher, P., Smith, M. S., et al (2006) The dex/CRH test-Is it better than the DST? Psychoneuroendocrinology 31, 889-894.
31. Young, A. H., Gallagher, P., Watson, S., et al (2004) Improvements in neurocognitive function and mood following adjunctive treatment with mifepristone (RU-486) in bipolar disorder. Neuropsychopharmacology, 29, 1538-1545.