Activation-coupled membrane-type 1 matrix metalloproteinase membrane trafficking

Biochemical Journal

Volumn 407, Issue 2, 2007, Pages 171-177

  Wu, Yi I ^a,e   Munshi, Hidayatullah G ^a   Snipas, Scott J ^b   Salvesen, Guy S ^b   Fridman, Rafael ^c   Stack, M Sharon ^a,d  

^a NORTHWESTERN UNIVERSITY   (United States)

^b BURNHAM INSTITUTE   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d University of Missouri   (United States)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

1 PI ( 1 proteinase inhibitor); Furin; MT1 MMP (membrane type 1 matrix metalloproteinase); Trafficking

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; BIOLOGICAL MEMBRANES; CELL CULTURE; COLLAGEN; ONCOLOGY;

FURIN; METALLOPROTEINASE;

ENZYMES;

ALPHA 1 ANTITRYPSIN; ENZYME PRECURSOR; FURIN; MATRIX METALLOPROTEINASE 14;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CANCER GROWTH; CELL SURFACE; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; WILD TYPE;

ANIMALS; CERCOPITHECUS AETHIOPS; COLLAGEN; COS CELLS; ENZYME ACTIVATION; ENZYME PRECURSORS; GLYCOSYLATION; HUMANS; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 2; PROTEASE INHIBITORS; PROTEIN ENGINEERING; PROTEIN TRANSPORT; TRANSFECTION;

EID: 35048822384     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20070552     Document Type: Article

References (29)

1. Sternlicht, M. D. and Werb, Z. (2001) How matrix metalloproteinases regulate cell behavior. Annu. Rev. Cell Dev. Biol. 17, 463-516
2. Mayer, G., Boileau, G. and Bendayan, M. (2003) Furin interacts with proMT1-MMP and integrin αV at specialized domains of renal cell plasma membrane. J. Cell Sci. 116, 1763-1773
3. Holmbeck, K., Bianco, P., Caterina, J., Yamada, S., Kromer, M., Kuznetsov, S. A., Mankani, M., Robey, P. G., Poole, A. R., Pidoux, I. et al. (1999) MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell 99, 81-92
4. Hotary, K., Allen, E., Punturieri, A., Yana, I. and Weiss, S. J. (2000) Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3. J. Cell Biol. 149, 1309-1323
5. Hotary, K. B., Allen, E. D., Brooks, P. C., Dana, N. S., Long, M. W. and Weiss, S. J. (2003) Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix. Cell 114, 33-45
6. Jiang, A., Lehti, K., Wang, X., Weiss, S. J., Keski-Oja, J. and Pei, D. (2001) Regulation of membrane-type matrix metalloproteinase 1 activity by dynamin-mediated endocytosis. Proc. Natl. Acad. Sci. U.S.A. 98, 13693-13698
7. Wu, Y. I., Munshi, H. G., Sen, R., Snipas, S. J., Salvesen, G. S., Fridman, R. and Stack, M. S. (2004) Glycosylation broadens the substrate profile of membrane type 1 matrix metalloproteinase. J. Biol. Chem. 279, 8278-8289
8. Yana, I. and Weiss, S. J. (2000) Regulation of membrane type-1 matrix metalloproteinase activation by proprotein convertases. Mol. Biol. Cell 11, 2387-2401
9. Toth, M., Hernandez-Barrantes, S., Osenkowski, P., Bernardo, M. M., Gervasi, D. C., Shimura, Y., Meroueh, O., Kotra, L. P., Galvez, B. G., Arroyo, A. G. et al. (2002) Complex pattern of membrane type 1 matrix metalloproteinase shedding. Regulation by autocatalytic cells surface inactivation of active enzyme. J. Biol. Chem. 277, 26340-26350
10. Thomas, G. (2002) Furin at the cutting edge: from protein traffic to embryogenesis and disease. Nat. Rev. Mol. Cell Biol. 3, 753-766
11. Brennan, S. O., Owen, M. C., Boswell, D. R., Lewis, J. H. and Carrell, R. W. (1984) Circulating prealbumin associated with a variant proteinase inhibitor. Biochim. Biophys. Acta 802, 24-28
12. Anderson, E. D., Thomas, L., Hayflick, J. S. and Thomas, G. (1993) Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed α1-antitrypsin variant. J. Biol. Chem. 268, 24887-24891
13. Toth, M., Bernardo, M. M., Gervasi, D. C., Soloway, P. D., Wang, Z., Bigg, H. F., Overall, C. M., DeClerck, Y. A., Tschesche, H., Cher, M. L. et al. (2000) Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (membrane type 1)-MMP-dependent activation of pro-MMP-2. J. Biol. Chem. 275, 41415-41423
14. Ellerbroek, S. M., Wu, Y. I., Overall, C. M. and Stack, M. S. (2001) Functional interplay between type I collagen and cell surface matrix metalloproteinase activity. J. Biol. Chem. 276, 24833-24842
15. Munshi, H. G., Wu, Y. I., Ariztia, E. V. and Stack, M. S. (2002) Calcium regulation of matrix metalloproteinase-mediated migration in oral squamous cell carcinoma cells. J. Biol. Chem. 277, 41480-41488
16. Tam, E. M., Wu, Y. I., Butler, G. S., Stack, M. S. and Overall, C. M. (2002) Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage. J. Biol. Chem. 277, 39005-39014
17. Munshi, H. G. and Stack, M. S. (2002) Analysis of matrix degradation. Methods Cell Biol. 69, 195-205
18. Munshi, H. G., Wu, Y. I., Mukhopadhyay, S., Sassano, A., Koblinski, J. E., Platanias, L. C. and Stack, M. S. (2004) Differential regulation of membrane type I-matrix metalloproteinase activity by ERK1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinase-2 expression controls TGFβ1-induced pericellular collagenolysis. J. Cell Biol. 279, 39042-39050
19. Molloy, S. S., Anderson, E. D., Jean, F. and Thomas, G. (1999) Bi-cycling the furin pathway: from TGN localization to pathogen activation and embryogenesis. Trends Cell Biol. 9, 28-35
20. Watanabe, T., Nakagawa, T., Ikemizu, J., Nagahama, M., Murakami, K. and Nakayama, K. (1992) Sequence requirements for precursor cleavage within the constitutive secretory pathway. J. Biol. Chem. 267, 8270-8274
21. Oda, K., Misumi, Y., Sohda, M., Takami, N., Sakaki, Y. and Ikehara, Y. (1991) Selective processing of proalbumin determined by site-specific mutagenesis. Biochem. Biophys. Res. Commun. 175, 690-696
22. Pelham, H. R. (1991) Multiple targets for brefeldin A. Cell 67, 449-451
23. Lehmann, M., Rigot, V., Seidah, N. G., Marvaldi, J. and Lissitzky, J. C. (1996) Lack of integrin α-chain endoproteolytic cleavage in furin-deficient human colon adenocarcinoma cells LoVo. Biochem. J. 317, 803-809
24. Sato, T., Kondo, T., Fujisawa, T., Seiki, M. and Ito, A. (1999) Furin-independent pathway of membrane type 1-matrix metalloproteinase activation in rabbit dermal fibroblasts. J. Biol. Chem. 274, 37280-37284
25. Mazzone, M., Baldassarre, M., Beznoussenko, G., Giacchetti, G., Cao, J., Zucker, S., Luini, A. and Buccione, R. (2004) Intracellular processing and activation of membrane type 1 matrix metalloprotease depends on its partitioning into lipid domains. J. Cell. Sci. 117, 6275-6287
26. Remacle, A. G., Rozanov, D. V., Fugere, M., Day, R. and Strongin, A. Y. (2006) Furin regulates the intracellular activation and the uptake rate of cell surface-associated MT1-MMP. Oncogene 25, 5648-5655
27. Cao, J., Hymowitz, M., Conner, C., Bahou, W. F. and Zucker, S. (2000) The propeptide domain of membrane type 1-matrix metalloproteinase acts as an intramolecular chaperone when expressed in trans with the mature sequence in COS-1 cells. J. Biol. Chem. 275, 29648-29653
28. Cao, J., Drews, M., Lee, H. M., Conner, C., Bahou, W. F. and Zucker, S. (1998) The propeptide domain of membrane type 1 matrix metalloproteinase is required for binding of tissue inhibitor of metalloproteinases and for activation of pro-gelatinase A. J. Biol. Chem. 273, 34745-34752
29. Okumura, Y., Sato, H., Seiki, M. and Kido, H. (1997) Proteolytic activation of the precursor of membrane type 1 matrix metalloproteinase by human plasmin. A possible cell surface activator. FEBS Lett. 402, 181-184