Relationship between parathyroid hormone and cardiac abnormalities in chronic dialysis patients

Internal Medicine

Volumn 46, Issue 18, 2007, Pages 1507-1512

  Fujii, Hideki ^a   Kim, Jong Il ^b   Abe, Takaya ^a   Umezu, Michio ^a   Fukagawa, Masafumi ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Chibune Hospital   (Japan)

Author keywords

Cardiac abnormalities; Hemodialysis; Left ventricular hypertrophy; Parathyroid hormone

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; CALCIUM CARBONATE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; INSULIN; ORAL ANTIDIABETIC AGENT; PARATHYROID HORMONE; SEVELAMER; VITAMIN D;

ADULT; AGED; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORRELATION ANALYSIS; DIABETES MELLITUS; DIASTOLIC DYSFUNCTION; DISEASE ASSOCIATION; ECHOCARDIOGRAPHY; FEMALE; HEART DISEASE; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE MASS; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE SEPTUM; HEMODIALYSIS; HEMODIALYSIS PATIENT; HIGH RISK POPULATION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; PARATHYROID HORMONE BLOOD LEVEL; PATHOGENESIS; RISK FACTOR; SYSTOLIC DYSFUNCTION;

AGED; ECHOCARDIOGRAPHY; FEMALE; HEART VENTRICLES; HUMANS; HYPERTROPHY, LEFT VENTRICULAR; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; PARATHYROID HORMONE; RENAL DIALYSIS; VENTRICULAR FUNCTION, LEFT;

EID: 34948904385     PISSN: 09182918     EISSN: 13497235     Source Type: Journal    
DOI: 10.2169/internalmedicine.46.0269     Document Type: Article

References (20)

1. Patient Registration Committee, Japanese Society for Dialysis Therapy, Tokyo, Japan. An overview of regular dialysis treatment in Japan as of 31 December 2003. Ther Apher Dial 9: 431-458, 2005.
2. Parfrey PS, Foley RN, Harnett JD, Kent GM, Murray DC, Barre PE. Outcome and risk factors for left ventricular disorders in chronic uraemia. Nephrol Dial Transplant 11: 1277-1285, 1996.
3. Foley RN, Parfrey PS, Harnett JD, et al. Clinical and echocardiographic disease in patients starting end-stage renal disease therapy. Kidney Int 47: 186-192, 1995.
4. Harnett JD, Parfrey PS, Griffiths SM, Gault MH, Barre P, Guttmann RD. Left ventricular hypertrophy in end-stage renal disease. Nephron 48 (2): 107-115, 1988.
5. Bogin E, Massry SG, Harary I. Effect of parathyroid hormone on rat heart cells. J Clin Invest 67: 1215-1227, 1981.
6. Amann K, Ritz E, Wiest G, Klaus G, Mall G. A role of parathyroid hormone for the activation of cardiac fibroblasts in uremia. J Am Soc Nephrol 4 (10): 1814-1819, 1994.
7. Andersson P, Rydberg E, Willenheimer R. Primary hyperparathyroidism and heart disease - a review. Eur Heart J 25: 1776-1787, 2004.
8. Stefenelli T, Abela C, Frank H, et al. Cardiac abnormalities in patients with primary hyperparathyroidism: implications for follow-up. J Clin Endocrinol Metab 82: 106-112, 1997.
9. Verdecchia P, Carini G, Circo A, et al. Left ventricular mass and cardiovascular morbidity in essential hypertension: the MAVI study. J Am Coll Cardiol 38: 1829-1835, 2001.
10. Langle F, Abela C, Koller-Strametz J, et al. Primary hyperparathyroidism and the heart: cardiac abnormalities correlated to clinical and biochemical data. World J Surg 18: 619-624, 1994.
11. Piovesan A, Molineri N, Casasso, F, et al. Left ventricular hypertrophy in primary hyperparathyroidism. Effects of successful parathyroidectomy. Clin Endocrinol 50: 321-328, 1999.
12. Strozecki P, Adamowicz A, Nartowicz E, Odrowaz-Sypniewska G, Wlodarczyk Z, Manitius J. Parathormon, calcium, phosphorus, and left ventricular structure and function in normotensive hemodialysis patients. Ren Fail 23: 115-126, 2001.
13. Fagugli RM, Pasini P, Quintaliani G, et al. Association between extracellular water, left ventricular mass and hypertension in haemodialysis patients. Nephrol Dial Transplant 18: 2332-2338, 2003.
14. Katoh Y, Klein KL, Kaplan RA, Sanborn WG, Kurokawa K. Parathyroid hormone has a positive inotropic action in the rat. Endocrinology 109: 2252-1154, 1981.
15. Drueke T, Fauchet M, Fleury J, et al. Effect of parathyroidectomy on left-ventricular function in haemodialysis patients. Lancet 1: 112-114, 1980.
16. Goto N, Tominaga Y, Matsuoka S, et al. Cardiovascular complications caused by advanced secondary hyperparathyroidism in chronic dialysis patients; special focus on dilated cardiomyopathy. Clin Exp Nephrol 9: 138-141, 2005.
17. Hara S, Ubara Y, Arizono K, et al. Relation between parathyroid hormone and cardiac function in long-term hemodialysis patients. Miner Electrolyte Metab 21: 72-76, 1995.
18. Fellner SK, Lang RM, Neumann A, Bushinsky DA, Borow KM. Parathyroid hormone and myocardial performance in dialysis patients. Am J Kidney Dis 18: 320-325, 1991.
19. Park CW, Oh YS, Shin YS, et al. Intravenous calcitriol regresses myocardial hypertrophy in hemodialysis patients with secondary hyperparathyroidism. Am J Kidney Dis 33: 73-81, 1999.
20. Achinger SG, Ayus JC. The role of vitamin D in left ventricular hypertrophy and cardiac function. Kidney Int (Suppl.) 95: S37-S42, 2005. Review.