Tachyphylaxis of the ECL-cell response to PACAP: Receptor desensitization and/or depletion of secretory products

British Journal of Pharmacology

Volumn 152, Issue 2, 2007, Pages 240-248

  Bernsand, M ^a   Hakanson R ^a   Norlen P ^a,b  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

ECL cells; Gastrin; Histamine; Histidine decarboxylase; Microdialysis; PACAP; Pancreastatin; Rat stomach; Somatostatin

Indexed keywords

CELL MARKER; GASTRIN; HISTAMINE; HISTIDINE DECARBOXYLASE; HORMONE RECEPTOR BLOCKING AGENT; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE 27; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR; OMEPRAZOLE; PANCREASTATIN; PEPTIDE; PRL 2903; SOMATOSTATIN; SOMATOSTATIN RECEPTOR 2 ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL FUNCTION; CONTINUOUS INFUSION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE INCREASE; ENTEROCHROMAFFIN LIKE CELL; FEMALE; GASTRIN BLOOD LEVEL; HISTAMINE METABOLISM; HISTAMINE RELEASE; LOW DRUG DOSE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION; STOMACH MUCOSA; TACHYPHYLAXIS;

ANIMALS; ENTEROCHROMAFFIN-LIKE CELLS; FEMALE; GASTRINS; HISTAMINE; HISTIDINE DECARBOXYLASE; MICRODIALYSIS; PANCREATIC HORMONES; PEPTIDES, CYCLIC; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SOMATOSTATIN; SOMATOSTATIN; STOMACH; TACHYPHYLAXIS;

EID: 34948896419     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707385     Document Type: Article

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