Methodological evaluation on PCR-DGGE technique in detecting DNA mutation and single nucleotide polymorphism

Journal of Sichuan University (Medical Science)

Volumn 38, Issue 5, 2007, Pages 882-884

  Lu, Xiao Jun ^a   Jia, Yong Qian ^a   Fan, Hong ^a   Zhang, Lei ^a   Jia, Jin ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

DGGE; DNA sequencing analysis; Mutation; Polymorphism analysis

Indexed keywords

EID: 34948884687     PISSN: 1672173X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Fischer SG, Lerman LS. DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels; correspondence with melting theory. Proc Natl Acad Sci U SA, 1983;80(6);1579-1583.
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7. Fodde R, Losekoot M. Mutation detection by denaturing gradient gel electrophoresis (DGGE). Hum Mutat,1994;3(2):83-94.
8. Guldberg P, Guttler F. Mutation screening versus gene scanning for genotyping phenylketonuria patients. J Inherit Metab Dis, 1994;17(3):359-361.