Structure and phospholipase function of peroxiredoxin 6: Identification of the catalytic triad and its role in phospholipid substrate binding

Journal of Lipid Research

Volumn 48, Issue 10, 2007, Pages 2306-2318

  Manevich, Yefim ^a   Reddy, Konda S ^b   Shuvaeva, Tea ^a   Feinstein, Sheldon I ^a   Fisher, Aron B ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Circular dichroism; Fluorescence resonance energy transfer; Lipid binding; Liposomes; Peroxidase; Site directed mutagenesis

Indexed keywords

PEROXIREDOXIN; PHOSPHOLIPASE; PHOSPHOLIPASE A2; PHOSPHOLIPID; PROTEIN PEROXIREDOXIN 6; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; FLUORESCENCE RESONANCE ENERGY TRANSFER; LIGHT SCATTERING; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE;

ANIMALS; CATALYSIS; CIRCULAR DICHROISM; GLUTATHIONE PEROXIDASE; HYDROLYSIS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MUTAGENESIS, SITE-DIRECTED; MUTATION; PEROXIREDOXIN VI; PHOSPHOLIPASES; PHOSPHOLIPIDS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RATS; RECOMBINANT PROTEINS;

EID: 34948878714     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M700299-JLR200     Document Type: Article

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