Periportal and sinusoidal liver dendritic cells suppressing T helper type 1-mediated hepatitis

Gut

Volumn 56, Issue 10, 2007, Pages 1445-1451

  Watanabe, Tomohiro ^a   Katsukura, Hiroaki ^a   Chiba, Tsutomu ^a   Kita, Toru ^a   Wakatsuki, Yoshio ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD11 ANTIGEN; CD4 ANTIGEN; CYTOKINE; LIPOSOME; OVALBUMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CELL THERAPY; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; HEPATITIS; HUMORAL IMMUNITY; IMMUNOREACTIVITY; INHIBITION KINETICS; LIVER CELL; LIVER INJURY; LIVER PROTECTION; LIVER SINUSOID; MALE; MOUSE; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; TH1 CELL; TH2 CELL;

ADMINISTRATION, ORAL; ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD11C; APOPTOSIS; CELL DIFFERENTIATION; CYTOKINES; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; HEPATITIS, AUTOIMMUNE; IMMUNE TOLERANCE; LIVER; MALE; MICE; MICE, INBRED BALB C; OVALBUMIN; PORTAL VEIN; SPLEEN; TH1 CELLS; TH2 CELLS;

EID: 34948860483     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2007.121251     Document Type: Article

References (29)

1. Crispe IN, Giannandrea M, Klein I, et al. Cellular and molecular mechanisms of liver tolerance. Immunol Rev 2006;213:101- 18.
2. Crispe IN. Hepatic T cells and liver tolerance. Nat Rev Immunol 2003;3:51-62.
3. Thomson AW, Lu L. Are dendritic cells the key to liver transplant tolerance? Immunol Today 1999;20:27-32.
4. Thomson AW, Drakes ML, Zahorchak AF, et al. Hepatic dendritic cells: immunobiology and role in liver transplantation. J Leukoc Biol 1999;66:322-30.
5. Callery MP, Kamei T, Flye MW. The effect of portacaval shunt on delayed-hypersensitivity responses following antigen feeding. J Surg Res 1989;46:391-4.
6. Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000;343:230-8.
7. Lau AH, Thomson AW. Dendritic cells and immune regulation in the liver. Gut 2003;52:307-14.
8. Watanabe T, Katsukura H, Shirai Y, et al. A liver tolerates a portal antigen by generating CD11c cells, which select Fas Ligand Th2 cells via apoptosis. Hepatology 2003;38:403-12.
9. Knolle PA, Schmitt E, Jin S, et al. Induction of cytokine production in naive CD4(+) T cells by antigen- presenting murine liver sinusoidal endothelial cells but failure to induce differentiation toward Th1 cells. Gastroenterology 1999;116:1428-40.
10. Khanna A, Morelli AE, Zhong C, et al. Effects of liver-derived dendritic cell progenitors on Th1- and Th2- like cytokine responses in vitro and in vivo. J Immunol 2000;164:1346-54.
11. Czaja AJ, Cookson S, Constantini PK, et al. Cytokine polymorphisms associated with clinical features and treatment outcome in type 1 autoimmune hepatitis. Gastroenterology 1999;117:645-52.
12. Harada K, Van de Water J, Leung PS, et al. In situ nucleic acid hybridization of cytokines in primary biliary cirrhosis: predominance of the Th1 subset. Hepatology 1997;25:791-6.
13. Bo X, Broome U, Remberger M, et al. Tumour necrosis factor alpha impairs function of liver derived T lymphocytes and natural killer cells in patients with primary sclerosing cholangitis. Gut 2001;49:131- 41.
14. Nishimura T, Ohta A. A critical role for antigen-specific Th1 cells in acute liver injury in mice. J Immunol 1999;162:6503-9.
15. Tjandra K, Sharkey KA, Swain MG. Progressive development of a Th1-type hepatic cytokine profile in rats with experimental cholangitis. Hepatology 2000;31:280-90.
16. Watanabe T, Yoshida M, Shirai Y, et al. Administration of an antigen at a high dose generates regulatory CD4+ T cells expressing CD95 ligand and secreting IL4 in the liver. J Immunol 2002;168:2188-99.
17. Watanabe T, Yamori M, Kita T, et al. CD4+CD25+ T cells regulate colonic localization of CD4 T cells reactive to a microbial antigen. Inflamm Bowel Dis 2005;11:541-50.
18. Watanabe T, Katsukura H, Shirai Y, et al. Helper CD4 T cells for IgE response to a dietary antigen develop in the liver. J Allergy Clin Immunol 2003;111:1375-85.
19. Watanabe T, Kitani A, Murray PJ, et al. Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis. Immunity 2006;25:473-85.
20. Lu L, Bonham CA, Liang X, et al. Liver-derived DEC205+B220+CD19- dendritic cells regulate T cell responses. J Immunol 2001;166:7042-52.
21. Limmer A, Ohl J, Wingender G, et al. Cross-presentation of oral antigens by liver sinusoidal endothelial cells leads to CD8 T cell tolerance. Eur J Immunol 2005;35:2970-81.
22. Knolle PA. Involvement of the liver in the induction of CD8 T cell tolerance towards oral antigen. Z Gastroenterol 2006;44:51-6.
23. Hiasa Y, Akbar SM, Abe M, et al. Dendritic cell subtypes in autoimmune liver diseases; decreased expression of HLA DR and CD123 on type 2 dendritic cells. Hepatol Res 2002;22:241-249.
24. Akbar SM, Yamamoto K, Miyakawa H, et al. Peripheral blood T-cell responses to pyruvate dehydrogenase complex in primary biliary cirrhosis: role of antigen-presenting dendritic cells. Eur J Clin Invest 2001;31:639-46.
25. Kanto T, Hayashi N, Takehara T, et al. Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals. J Immunol 1999;162:5584- 91.
26. Sicherer S. Food allergy. Lancet 2002;360:701.
27. Collins AM, Leach S, Payne J, et al. A role for the hepatobiliary system in IgE-mediated intestinal inflammation in the rat. Clin Exp Allergy 1999;29:262-70.
28. Ito K, Inagaki-Ohara K, Murosaki S, et al. Murine model of IgE production with a predominant Th2-response by feeding protein antigen without adjuvants. Eur J Immunol 1997;27:3427-37.
29. Legendre C, Caillat-Zucman S, Samuel D, et al. Transfer of symptomatic peanut allergy to the recipient of a combined liver-and-kidney transplant. N Engl J Med 1997;337:822-4.