Dermatoporosis: A chronic cutaneous insufficiency/fragility syndrome - Clinicopathological features, mechanisms, prevention and potential treatments

Dermatology

Volumn 215, Issue 4, 2007, Pages 284-294

  Kaya, Gürkan ^a   Saurat, Jean Hilaire ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

CD44; Dermatoporosis; Hyaluronate; Skin aging

Indexed keywords

ARTICLE; CHRONIC CUTANEOUS INSUFFICIENCY; CLINICAL FEATURE; CUTANEOUS PARAMETERS; DERMATOPOROSIS; DISEASE SEVERITY; FRAGILITY SYNDROME; HUMAN; PATHOGENESIS; PRIORITY JOURNAL; PURPURA; SKIN ATROPHY; SKIN BLEEDING; SKIN DISEASE; SKIN INJURY; SKIN NECROSIS; SKIN SCAR;

AGE FACTORS; ATROPHY; HUMANS; PROGNOSIS; SEVERITY OF ILLNESS INDEX; SKIN; SKIN AGING; SKIN DISEASES;

EID: 34948843556     PISSN: 10188665     EISSN: None     Source Type: Journal    
DOI: 10.1159/000107621     Document Type: Article

References (41)

1. Saurat JH: Quand la peau devient insuffisante (editorial). Méd Hyg 2004;2472:476.
2. Saurat JH: Dermatoporosis. The functional side of skin aging (editorial). Dermatology 2007;215:271-272.
3. Colomb D, Pinçon JA, Lartaud J: Individualisation anatomo-clinique d'une forme méconnue de la peau sénile: les pseudo-cicatrices stellaires spontanées. Leurs rapports avec le purpura de Bateman. Ann Dermatol Syphil 1967;94:273-286.
4. Colomb D: Stellate spontaneous pseudoscars: senile and presenile forms, especially those forms caused by prolonged corticoid therapy. Arch Dermatol 1972;105:551-554.
5. Prins C: L'insuffisance cutanée. Méd Hyg 2004;2472:478-480.
6. Schoepe S, Schäcke H, May E, Asadullah K: Glucocorticoid therapy-induced skin atrophy. Exp Dermatol 2006;15:406-420.
7. Tomic-Canic M, Brem H: Gene array technology and pathogenesis of chronic wounds. Am J Surg 2004;188(1A suppl):67-72.
8. Ralston SH, De Crombrugghe B: Genetic regulation of bone mass and susceptibility to osteoporosis. Gene Dev 2006;20:2492-2506.
9. Robert L, Labat-Robert J: Aging of connective tissues: from genetic to epigenetic mechanisms. Biogerontology 2000;1:123-131.
10. Giacomoni PU, Rein G: Factors of skin ageing share common mechanisms. Biogerontology 2001;2:219-229.
11. Hornebeck W: Down-regulation of tissue inhibitor of matrix metalloprotease-1 (TIMP-1) in aged human skin contributes to matrix degradation and impaired cell growth and survival. Pathol Biol 2003;51:569-573.
12. Meyer MA, Chawla KK: Mechanical Behavior of Materials. Upper Saddle River, Prentice-Hall, 1999, pp 98-103.
13. Toole BP, Lowther DA: The organisation of the hexosamine containing compounds in bovine skin. Biochim Biophys Acta 1966;121:315-322.
14. Harkness RD: Functional aspects of connective tissues of skin;in Balazes EA (ed): Chemistry and Molecular Biology of InterCellular Matrix. London, Academic Press, 1970, vol 3, pp 1309-1340.
15. Viidik A, Danielsen CC, Oxlund HC: On fundamental and phenomenological models, structure and mechanical properties of collagen, elastin and glycosaminoglycan complexes. Biorheology 1982;19:437-451.
16. Silver FH: Biological Materials: Structure, Mechanical Properties, and Modeling of Soft Tissues. New York, New York University Press, 1987, pp 75-79.
17. Dunn MG, Silver FH: Viscoelastic behavior of human connective tissues: relative contribution of viscous and elastic components. Connect Tissue Res 1983;12:59-70.
18. Silver FH, Kato YP, Ohno M, Wasserman AJJ: Analysis of mammalian connective tissue: relationship between hierarchical structures and mechanical properties. J Long Term Eff Med Implants 1992;2:165-198.
19. Wainwright SA, Biggs WD, Curry JD, Cosline JM: Mechanical Designs in Organisms. London, Arnold, 1976.
20. Silver FH, Seehra GP, Freeman JW, DeVore D: Viscoelastic properties of young and old human dermis: a proposed molecular mechanism for elastic energy storage in collagen and elastin. J Appl Polym Sci 2002;86:1978-1985.
21. Arumugam V, Naresh MD, Sanjeevi R: Effect of strain rate on the fracture behaviour of skin. J Biosci 1994;19:307-313.
22. Kamath YK, Weigmann HD: Fractography of human hair. J Appl Polym Sci 1982;27:3809-3823.
23. Arumugam V, Naresh MD, Somanathan N, Sanjeevi R: Effect of strain rate on the fracture behaviour of collagen. J Mater Sci 1992;27:2649-2652.
24. Arumugam V, Sanjeevi R: Effect of strain rate on the mode of fracture in elastoidin. J Mater Sci 1987;22:2691-2694.
25. Passeron T, Ortonne JP: Skin ageing and its prevention (in French). Presse Méd 2003;32:1474-1482.
26. Ma W, Wlaschek M, Tantcheva-Poor I, Schneider LA, Naderi L, Razi-Wolf Z, Schuller J, Scharffetter-Kochanek K: Chronological ageing and photoageing of the fibroblasts and the dermal connective tissue. Clin Exp Dermatol 2001;26:592-599.
27. Sellheyer K: Pathogenesis of solar elastosis: synthesis or degradation? J Cutan Pathol 2003;30:123-127.
28. Calikoglu E, Sorg O, Tran C, Grand D, Carraux P, Saurat JH, Kaya G: UVA and UVB decrease the expression of CD44 and hyaluronate in mouse epidermis which is counteracted by topical retinoids. Photochem Photobiol 2006;82:1342-1347.
29. Ghersetich I, Lotti T, Campanile G, Grappone C, Dini G: Hyaluronic acid in cutaneous intrinsic aging. Int J Dermatol 1994;33:119-122.
30. Kaya G, Tran C, Sorg O, Hotz R, Grand D, Carraux P, Didierjean L, Stamenkovic I, Saurat JH: Hyaluronate fragments reverse skin atrophy by a CD44-dependent mechanism. PLoS Med 2006;3:e493.
31. Fraser JRE, Laurent TC: Turnover and metabolism of hyaluronan: the biology of hyaluronan. CIBA Found Symp 1989;143:41-59.
32. Laurent TC, Fraser JR: Hyaluronan. FASEB J 1992;6:2397-2404. 33 Stamenkovic I, Aruffo A, Amiot M, Seed B: The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronatebearing cells. EMBO J 1991;10:343-348.
33. Bennett KL, Jackson DG, Simon JC, Tanczos E, Peach R, Modrell B, Stamenkovic I, Plowman G, Aruffo A: CD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factor. J Cell Biol 1995;128:687-698.
34. Kaya G, Rodriguez I, Jorcano JL, Vassalli P, Stamenkovic I: Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation. Genes Dev 1997;11:996-1007.
35. Kaya G, Tran C, Sorg O, Hotz R, Grand D, Carraux P, Didierjean L, Stamenkovic I, Saurat JH: CD44-dependent mouse skin hyperplasia induced by topical hyaluronate fragments. J Invest Dermatol 2004;123:A2.
36. Didierjean L, Carraux P, Grand D, Sass JO, Nau H, Saurat JH: Topical retinaldehyde increases skin content of retinoic acid and exerts biologic activity in mouse skin. J Invest Dermatol 1996;107:714-719.
37. Xiao JH, Feng X, Di W, Peng ZH, Li LA, Chambon P, Voorhees JJ: Identification of heparin-binding EGF-like growth factor as a target in intercellular regulation of epidermal basal cell growth by suprabasal retinoic acid receptors. EMBO J 1999;18:1539-1548.
38. Margelin D, Medaisko C, Lombard D, Picard J, Fourtanier A: Hyaluronic acid and dermatan sulfate are selectively stimulated by retinoic acid in irradiated and nonirradiated hairless mouse skin. J Invest Dermatol 1996;106:505-509.
39. Tammi R, Ripellino JA, Margolis RU, Maibach HI, Tammi M: Hyaluronate accumulation in human epidermis treated with retinoic acid in skin organ culture. J Invest Dermatol 1989;92:326-332.
40. Lundin A, Berne B, Michaelsson G: Topical retinoic acid treatment of photoaged skin: its effects on hyaluronan distribution in epidermis and on hyaluronan and retinoic acid in suction blister fluid. Acta Derm Venereol 1992;72:423-427.
41. Kaya G, Grand D, Hotz R, Augsburger E, Carraux P, Didierjean L, Saurat JH: Upregulation of CD44 and hyaluronate synthases by topical retinoids in mouse skin. J Invest Dermatol 2005;124:284-287.