Role of Ser216 in the mechanism of action of membrane-bound lytic transglycosylase B: Further evidence for substrate-assisted catalysis

FEBS Letters

Volumn 581, Issue 25, 2007, Pages 4988-4992

  Reid, Christopher W ^a   Legaree, Blaine A ^a   Clarke, Anthony J ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

1,6 anhydromuropeptide; HPAEC; Lytic transglycosylase; Peptidoglycan; Site directed mutagenesis; Substrate assisted catalysis; Zymogram

Indexed keywords

1,6 ANHYDROMURAMOYL; ENZYME; GLYCOSYLTRANSFERASE; HYDROLASE; MEMBRANE ENZYME; N ACETYLGLUCOSAMINE; N ACETYLMURAMIC ACID; SER 216 ENZYME; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL CELL; BINDING AFFINITY; CATALYSIS; ENZYME MECHANISM; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; WILD TYPE;

BACTERIAL PROTEINS; BINDING SITES; CATALYSIS; GLYCOSYLTRANSFERASES; KINETICS; MEMBRANE PROTEINS; MUTAGENESIS, SITE-DIRECTED; PEPTIDOGLYCAN; PSEUDOMONAS AERUGINOSA; SERINE;

BACTERIA (MICROORGANISMS); PSEUDOMONAS AERUGINOSA;

EID: 34948837924     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.09.037     Document Type: Article

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