Discovery and characterization of novel, potent, non-peptide parathyroid hormone-1 receptor antagonists

Journal of Medicinal Chemistry

Volumn 50, Issue 20, 2007, Pages 4789-4792

  McDonald, Iain M ^a   Austin, Carol ^a   Buck, Ildiko M ^a   Dunstone, David J ^a   Gaffen, John ^a   Griffin, Eric ^a   Harper, Elaine A ^a   Hull, Robert A D ^a   Kalindjian, S Barret ^a   Linney, Ian D ^a   Low, Caroline M R ^a   Patel, Dipa ^a   Pether, Michael J ^a   Raynor, Michelle ^a   Roberts, Sonia P ^a   Shaxted, Mark E ^a   Spencer, John ^a   Steel, Katherine I M ^a   Sykes, David A ^a   Wright, Paul T ^a   Xun, Wei ^a   more..

^a James Black Foundation   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1,3,4 BENZOTRIAZEPINE DERIVATIVE; CYCLIC AMP; PARATHYROID HORMONE RECEPTOR 1; PARATHYROID HORMONE RECEPTOR 1 ANTAGONIST; PARATHYROID HORMONE RECEPTOR 2; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DRUG POTENCY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; NONHUMAN; PROCESS OPTIMIZATION; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANIMALS; BENZAZEPINES; BINDING, COMPETITIVE; CELL LINE; CELL LINE, TUMOR; CRICETINAE; CRICETULUS; CYCLIC AMP; HUMANS; MICE; RADIOLIGAND ASSAY; RECEPTOR, PARATHYROID HORMONE, TYPE 1; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34948830135     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0707626     Document Type: Article

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