-
1
-
-
0031895616
-
Lipoprotein(a) and lipoprotein profile in healthy centenarians: A reappraisal of vascular risk factors
-
Baggio, G., Donazzan, S., Monti, D., Mari, D., Martini, S., Gabelli, C., Dalla Vestra, M., Previato, L., Guido, M., Pigozzo, S., Cortella, I., Crepaldi, G. & Franceschi, C. (1998) Lipoprotein(a) and lipoprotein profile in healthy centenarians: A reappraisal of vascular risk factors. FASEB J 12, 433-437.
-
(1998)
FASEB J
, vol.12
, pp. 433-437
-
-
Baggio, G.1
Donazzan, S.2
Monti, D.3
Mari, D.4
Martini, S.5
Gabelli, C.6
Dalla Vestra, M.7
Previato, L.8
Guido, M.9
Pigozzo, S.10
Cortella, I.11
Crepaldi, G.12
Franceschi, C.13
-
2
-
-
0034616230
-
Association between an interleukin-6 promoter and 3' flanking region haplotype and reduced Alzheimer's disease risk in a German population
-
Bagli, M., Papassotiropoulos, A., Knapp, M., Jessen, F., Luise Rao, M., Maier, W. & Heun, R. (2000) Association between an interleukin-6 promoter and 3' flanking region haplotype and reduced Alzheimer's disease risk in a German population. Neurosci Lett 283, 109-112.
-
(2000)
Neurosci Lett
, vol.283
, pp. 109-112
-
-
Bagli, M.1
Papassotiropoulos, A.2
Knapp, M.3
Jessen, F.4
Luise Rao, M.5
Maier, W.6
Heun, R.7
-
3
-
-
0043231492
-
Polymorphisms of the gene encoding the inflammatory cytokine interleukin-6 determine the magnitude of the increase in soluble interleukin-6 receptor levels in Alzheimer's disease. Results of a pilot study
-
Bagli, M., Papassotiropoulos, A., Hampel, H., Becker, K., Jessen, F., Burger, K., Ptok, U., Rao, M. L., Moller, H. J., Maier, W. & Heun, R. (2003) Polymorphisms of the gene encoding the inflammatory cytokine interleukin-6 determine the magnitude of the increase in soluble interleukin-6 receptor levels in Alzheimer's disease. Results of a pilot study. Eur Arch Psychiatry Clin Neurosci 253, 44-48.
-
(2003)
Eur Arch Psychiatry Clin Neurosci
, vol.253
, pp. 44-48
-
-
Bagli, M.1
Papassotiropoulos, A.2
Hampel, H.3
Becker, K.4
Jessen, F.5
Burger, K.6
Ptok, U.7
Rao, M.L.8
Moller, H.J.9
Maier, W.10
Heun, R.11
-
4
-
-
0034849867
-
A gender-dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity
-
Bonafe, M., Olivieri, F., Cavallone, L., Giovanetti, S., Mayegiani, F., Cardelli, M., Pieri, C., Marra, M., Antonicelli, R., Lisa, R., Rizzo, M. R., Prolisso, G., Monti, D. & Franceschi, C. (2001) A gender-dependent genetic predisposition to produce high levels of IL-6 is detrimental for longevity. Eur J Immunol 31, 2357-2361.
-
(2001)
Eur J Immunol
, vol.31
, pp. 2357-2361
-
-
Bonafe, M.1
Olivieri, F.2
Cavallone, L.3
Giovanetti, S.4
Mayegiani, F.5
Cardelli, M.6
Pieri, C.7
Marra, M.8
Antonicelli, R.9
Lisa, R.10
Rizzo, M.R.11
Prolisso, G.12
Monti, D.13
Franceschi, C.14
-
5
-
-
0024423898
-
Rapid detection and sequencing of alleles in the 3′ flanking region of the interleukin-6 gene
-
Bowcock, A. M., Ray, A., Erlich, H. & Sehga, P. B. (1989) Rapid detection and sequencing of alleles in the 3′ flanking region of the interleukin-6 gene. Nucleic Acids Res 17, 6855-6864.
-
(1989)
Nucleic Acids Res
, vol.17
, pp. 6855-6864
-
-
Bowcock, A.M.1
Ray, A.2
Erlich, H.3
Sehga, P.B.4
-
6
-
-
0035573649
-
Interleukin-6 gene-174g > c and -572g > c promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery
-
Brull, D. J., Montgomery, H. E., Sanders, J., Dhamrait, S., Luong, L., Rumley, A., Lowe, G. D. & Humphries, S. E. (2001) Interleukin-6 gene-174g > c and -572g > c promoter polymorphisms are strong predictors of plasma interleukin-6 levels after coronary artery bypass surgery. Arterioscler Thromb Vasc Biol 21, 1458-1463.
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1458-1463
-
-
Brull, D.J.1
Montgomery, H.E.2
Sanders, J.3
Dhamrait, S.4
Luong, L.5
Rumley, A.6
Lowe, G.D.7
Humphries, S.E.8
-
7
-
-
3242699699
-
Interleukin 6-174 G/C promoter gene polymorphism in centenarians: No evidence of association with human longevity or interaction with apolipoprotein E alleles
-
Capurso, C., Solfrizzi, V., D'Introno, A., Colacicco, A. M., Capurso, S. A., Semeraro, C., Capurso, A. & Panza, F. (2004) Interleukin 6-174 G/ C promoter gene polymorphism in centenarians: No evidence of association with human longevity or interaction with apolipoprotein E alleles. Exp Gerontol 39, 1109-1114.
-
(2004)
Exp Gerontol
, vol.39
, pp. 1109-1114
-
-
Capurso, C.1
Solfrizzi, V.2
D'Introno, A.3
Colacicco, A.M.4
Capurso, S.A.5
Semeraro, C.6
Capurso, A.7
Panza, F.8
-
8
-
-
2342495723
-
Modest implication of interleukin-6 promoter polymorphisms in longevity
-
Christiansen, L., Bathum, L., Andersen-Ranberg, K., Jeune, B. & Christensen, K. (2004) Modest implication of interleukin-6 promoter polymorphisms in longevity. Mech Ageing Dev 125, 391-395.
-
(2004)
Mech Ageing Dev
, vol.125
, pp. 391-395
-
-
Christiansen, L.1
Bathum, L.2
Andersen-Ranberg, K.3
Jeune, B.4
Christensen, K.5
-
9
-
-
0034101197
-
The 30 untranslated region of messenger RNA: A molecular hotspot for pathology?
-
Conne, B., Stutz, A. & Vassalli, J. D. (2000) The 30 untranslated region of messenger RNA: A molecular hotspot for pathology? Nat Med 6, 637-641.
-
(2000)
Nat Med
, vol.6
, pp. 637-641
-
-
Conne, B.1
Stutz, A.2
Vassalli, J.D.3
-
10
-
-
0027265827
-
Increased cytokine production in mononuclear cells of healthy elderly people
-
Fagiolo, U., Cossarizza, A., Scala, E., Fanales-Belasio, E., Ortolani, C., Cozzi, E., Monti, D., Franceschi, C. & Paganelli, R. (1993) Increased cytokine production in mononuclear cells of healthy elderly people. Eur J Immunol 23, 2375-2378.
-
(1993)
Eur J Immunol
, vol.23
, pp. 2375-2378
-
-
Fagiolo, U.1
Cossarizza, A.2
Scala, E.3
Fanales-Belasio, E.4
Ortolani, C.5
Cozzi, E.6
Monti, D.7
Franceschi, C.8
Paganelli, R.9
-
11
-
-
0033024330
-
Serum IL-6 level and the development of disability in older persons
-
Ferrucci, L., Harris, T. B., Guralnik, J. M., Tracy, R. P., Corti, M. C., Cohen, H. J., Penninx, B., Pahor, M., Wallace, R. & Havlik, R. J. (1999) Serum IL-6 level and the development of disability in older persons. J Am Geriatr Soc 47, 639-646.
-
(1999)
J Am Geriatr Soc
, vol.47
, pp. 639-646
-
-
Ferrucci, L.1
Harris, T.B.2
Guralnik, J.M.3
Tracy, R.P.4
Corti, M.C.5
Cohen, H.J.6
Penninx, B.7
Pahor, M.8
Wallace, R.9
Havlik, R.J.10
-
12
-
-
0032189103
-
The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis
-
Fishman, D., Faulds, G., Jeffery, R., Mohamed-Ali, V., Yudkin, J. S., Humphries, S. & Woo, P. (1998) The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 102, 1369-1376.
-
(1998)
J Clin Invest
, vol.102
, pp. 1369-1376
-
-
Fishman, D.1
Faulds, G.2
Jeffery, R.3
Mohamed-Ali, V.4
Yudkin, J.S.5
Humphries, S.6
Woo, P.7
-
13
-
-
1642462956
-
The -174G/C polymorphism of IL-6 is useful to screen old subjects at risk for atherosclerosis or to reach successful ageing
-
Giacconi, R., Cipriano, C., Albanese, F., Boccoli, G., Saba, V., Olivieri, F., Franceschi, C. & Mocchegiani, E. (2004) The -174G/C polymorphism of IL-6 is useful to screen old subjects at risk for atherosclerosis or to reach successful ageing. Exp Gerontol 39, 621-628.
-
(2004)
Exp Gerontol
, vol.39
, pp. 621-628
-
-
Giacconi, R.1
Cipriano, C.2
Albanese, F.3
Boccoli, G.4
Saba, V.5
Olivieri, F.6
Franceschi, C.7
Mocchegiani, E.8
-
14
-
-
33747139333
-
IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4
-
Grallert, H., Huth, C., Kolz, M., Meisinger, C., Herder, C., Strassburger, K., Giani, G., Wichmann, H. E., Adamski, J., Illig, T. & Rathmann, W. (2006) IL-6 promoter polymorphisms and quantitative traits related to the metabolic syndrome in KORA S4. Exp Gerontol 41, 737-745.
-
(2006)
Exp Gerontol
, vol.41
, pp. 737-745
-
-
Grallert, H.1
Huth, C.2
Kolz, M.3
Meisinger, C.4
Herder, C.5
Strassburger, K.6
Giani, G.7
Wichmann, H.E.8
Adamski, J.9
Illig, T.10
Rathmann, W.11
-
15
-
-
0033134682
-
Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly
-
Harris, T. B., Ferrucci, L., Tracy, R. P., Corti, M. C., Wacholder, S., Ettinger, W. H. Jr., Heimovitz, H., Cohen, H. J. & Wallace, R. (1999) Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am J Med 106, 506-512.
-
(1999)
Am J Med
, vol.106
, pp. 506-512
-
-
Harris, T.B.1
Ferrucci, L.2
Tracy, R.P.3
Corti, M.C.4
Wacholder, S.5
Ettinger, W.H.6
Heimovitz, H.7
Cohen, H.J.8
Wallace, R.9
-
16
-
-
12344285281
-
Interleukin-6 -174G/C polymorphism and longevity: A follow-up study
-
Hurme, M., Lehtimaki, T., Jylha, M., Karhunen, P. J. & Hervonen, A. (2005) Interleukin-6 -174G/C polymorphism and longevity: A follow-up study. Mech Ageing Dev 126, 417-418.
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 417-418
-
-
Hurme, M.1
Lehtimaki, T.2
Jylha, M.3
Karhunen, P.J.4
Hervonen, A.5
-
17
-
-
0043092123
-
Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain
-
Licastro, F., Grimaldi, L. M., Bonafe, M., Martina, C., Olivieri, F., Cavallone, L., Giovanietti, S., Masliah, E. & Franceschi, C. (2003) Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain. Neurobiol Aging 24, 921-926.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 921-926
-
-
Licastro, F.1
Grimaldi, L.M.2
Bonafe, M.3
Martina, C.4
Olivieri, F.5
Cavallone, L.6
Giovanietti, S.7
Masliah, E.8
Franceschi, C.9
-
18
-
-
0030857328
-
Polymorphisms of the interleukin-6 gene are associated with bone mineral density
-
Murray, R. E., McGuigan, F., Grant, S. F., Reid, D. M. & Ralston, S. H. (1997) Polymorphisms of the interleukin-6 gene are associated with bone mineral density. Bone 21, 89-92.
-
(1997)
Bone
, vol.21
, pp. 89-92
-
-
Murray, R.E.1
McGuigan, F.2
Grant, S.F.3
Reid, D.M.4
Ralston, S.H.5
-
19
-
-
0032914896
-
A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease
-
Papassotiropoulos, A., Bagli, M., Jessen, F., Bayer, T. A., Maier, W., Rao, M. L. & Heun, R. (1999) A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer's disease. Ann Neurol 45, 666-668.
-
(1999)
Ann Neurol
, vol.45
, pp. 666-668
-
-
Papassotiropoulos, A.1
Bagli, M.2
Jessen, F.3
Bayer, T.A.4
Maier, W.5
Rao, M.L.6
Heun, R.7
-
20
-
-
0032707262
-
Decreased frequency of apolipoprotein E epsilon4 allele from Northern to Southern Europe in Alzheimer's disease patients and centenarians
-
Panza, F., Solfrizzi, V., Torres, F., Mastroianni, F., Del Parigi, A., Colacicco, A. M., Basile, A. M., Capurso, C., Noya, R. & Capurso, A. (1999) Decreased frequency of apolipoprotein E epsilon4 allele from Northern to Southern Europe in Alzheimer's disease patients and centenarians. Neurosci Lett 277, 53-56.
-
(1999)
Neurosci Lett
, vol.277
, pp. 53-56
-
-
Panza, F.1
Solfrizzi, V.2
Torres, F.3
Mastroianni, F.4
Del Parigi, A.5
Colacicco, A.M.6
Basile, A.M.7
Capurso, C.8
Noya, R.9
Capurso, A.10
-
21
-
-
1542298274
-
Vascular genetic factors and human longevity
-
Panza, F., D'Introno, A., Colacicco, A. M., Capurso, C., Capurso, S., Kehoe, P. G., Capurso, A. & Solfrizzi, V. (2004) Vascular genetic factors and human longevity. Mech Ageing Dev 125, 169-178.
-
(2004)
Mech Ageing Dev
, vol.125
, pp. 169-178
-
-
Panza, F.1
D'Introno, A.2
Colacicco, A.M.3
Capurso, C.4
Capurso, S.5
Kehoe, P.G.6
Capurso, A.7
Solfrizzi, V.8
-
22
-
-
23244447027
-
Molecular determinants of human longevity. Chapter 7
-
In: (Ed. Makowski, G.) New York: Academic Press, Elsevier
-
Panza, F., D'Introno, A., Colacicco, A. M., Capurso, C., Palasciano, R., Capurso, S., Gadaleta, A., Capurso, A., Kehoe, P. G. & Solfrizzi, V. (2005) Molecular determinants of human longevity. Chapter 7. In: Advances in Clinical Chemistry 39 (Ed. Makowski, G.) pp. 185-210. New York: Academic Press, Elsevier.
-
(2005)
Advances in Clinical Chemistry
, vol.39
, pp. 185-210
-
-
Panza, F.1
D'Introno, A.2
Colacicco, A.M.3
Capurso, C.4
Palasciano, R.5
Capurso, S.6
Gadaleta, A.7
Capurso, A.8
Kehoe, P.G.9
Solfrizzi, V.10
-
23
-
-
4544272418
-
Association between longevity and cytokine gene polymorphisms. A study in Sardinian centenarians
-
Pes, G. M., Lio, D., Carru, C., Deiana, L., Baggio, G., Franceschi, C., Ferrucci, L., Oliveti, F., Scola, L., Crivello, A., Candore, G., Colonna-Romano, G. & Caruso, C. (2004) Association between longevity and cytokine gene polymorphisms. A study in Sardinian centenarians. Aging Clin Exp Res 16, 244-248.
-
(2004)
Aging Clin Exp Res
, vol.16
, pp. 244-248
-
-
Pes, G.M.1
Lio, D.2
Carru, C.3
Deiana, L.4
Baggio, G.5
Franceschi, C.6
Ferrucci, L.7
Oliveti, F.8
Scola, L.9
Crivello, A.10
Candore, G.11
Colonna-Romano, G.12
Caruso, C.13
-
24
-
-
0242500485
-
Interleukin-6-gene C/G 174 polymorphism in nonagenarian and octogenarian subjects in the BELFAST study. Reciprocal effects on IL-6, soluble IL-6 receptor and for IL-10 in serum and monocyte supernatants
-
Rea, I. M., Ross, O. A., Armstrong, M., McNerlan, S., Alexander, D. H., Curran, M. D. & Middleton, D. (2003) Interleukin-6-gene C/G 174 polymorphism in nonagenarian and octogenarian subjects in the BELFAST study. Reciprocal effects on IL-6, soluble IL-6 receptor and for IL-10 in serum and monocyte supernatants. Mech Ageing Dev 124, 555-561.
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 555-561
-
-
Rea, I.M.1
Ross, O.A.2
Armstrong, M.3
McNerlan, S.4
Alexander, D.H.5
Curran, M.D.6
Middleton, D.7
-
25
-
-
20444395843
-
Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: The cardiovascular health study
-
Reiner, A. P., Diehr, P., Browner, W. S., Humphries, S. E., Jenny, N. S., Cushman, M., Tracy, R. P., Walston, J., Lumley, T., Newman, A. B., Kuller, L. H. & Psaty, B. M. (2005) Common promoter polymorphisms of inflammation and thrombosis genes and longevity in older adults: The cardiovascular health study. Atherosclerosis 181, 175-183.
-
(2005)
Atherosclerosis
, vol.181
, pp. 175-183
-
-
Reiner, A.P.1
Diehr, P.2
Browner, W.S.3
Humphries, S.E.4
Jenny, N.S.5
Cushman, M.6
Tracy, R.P.7
Walston, J.8
Lumley, T.9
Newman, A.B.10
Kuller, L.H.11
Psaty, B.M.12
-
26
-
-
0037291273
-
Study of age-association with cytokine gene polymorphisms in an aged Irish population
-
Ross, O. A., Curran, M. D., Meenagh, A., Williams, F., Barnett, Y. A., Middleton, D. & Rea, I. M. (2003) Study of age-association with cytokine gene polymorphisms in an aged Irish population. Mech Ageing Dev 124, 199-206.
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 199-206
-
-
Ross, O.A.1
Curran, M.D.2
Meenagh, A.3
Williams, F.4
Barnett, Y.A.5
Middleton, D.6
Rea, I.M.7
-
27
-
-
0034711596
-
No association of serum levels of interleukin-6 and its soluble receptor components with a genetic variation in the 3'flanking region of the interleukin-6 gene in patients with multiple sclerosis
-
Schmidt, S., Papassotiropoulos, A., Bagli, M., Harzheim, M., Heun, R. & Klockgether, T. (2000) No association of serum levels of interleukin-6 and its soluble receptor components with a genetic variation in the 3'flanking region of the interleukin-6 gene in patients with multiple sclerosis. Neurosci Lett 294, 139-142.
-
(2000)
Neurosci Lett
, vol.294
, pp. 139-142
-
-
Schmidt, S.1
Papassotiropoulos, A.2
Bagli, M.3
Harzheim, M.4
Heun, R.5
Klockgether, T.6
-
28
-
-
33748787154
-
Sex differences in the association of apolipoprotein E and angiotensin-converting enzyme gene polymorphisms with healthy aging and longevity: A population-based study from Southern Italy
-
Seripa, D., Franceschi, M., Matera, M. G., Panza, F., Kehoe, P. G., Gravina, C., Orsitto, G., Solfrizzi, V., Di Minno, G., Dallapiccola, B. & Pilotto, A. (2006) Sex differences in the association of apolipoprotein E and angiotensin-converting enzyme gene polymorphisms with healthy aging and longevity: A population-based study from Southern Italy. J Gerontol A Biol Sci Med Sci 61, 918-923.
-
(2006)
J Gerontol A Biol Sci Med Sci
, vol.61
, pp. 918-923
-
-
Seripa, D.1
Franceschi, M.2
Matera, M.G.3
Panza, F.4
Kehoe, P.G.5
Gravina, C.6
Orsitto, G.7
Solfrizzi, V.8
Di Minno, G.9
Dallapiccola, B.10
Pilotto, A.11
-
29
-
-
0037042091
-
Effect of IL-6 polymorphism on risk of Alzheimer disease: Genotype-phenotype association study in Japanese cases
-
Shibata, N., Ohnuma, T., Takahashi, T., Baba, H., Ishizuka, T., Ohtsuka, M., Ueki, A., Nagao, M. & Arai, H. (2002) Effect of IL-6 polymorphism on risk of Alzheimer disease: Genotype-phenotype association study in Japanese cases. Am J Med Genet 114, 436-439.
-
(2002)
Am J Med Genet
, vol.114
, pp. 436-439
-
-
Shibata, N.1
Ohnuma, T.2
Takahashi, T.3
Baba, H.4
Ishizuka, T.5
Ohtsuka, M.6
Ueki, A.7
Nagao, M.8
Arai, H.9
-
30
-
-
0040780540
-
Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation
-
Terry, C. F., Loukaci, V. & Green, F. R. (2000) Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation. J Biol Chem 275, 18138-18144.
-
(2000)
J Biol Chem
, vol.275
, pp. 18138-18144
-
-
Terry, C.F.1
Loukaci, V.2
Green, F.R.3
-
31
-
-
0034792299
-
Lack of association between human longevity and polymorphisms of IL-1 cluster, IL-6, IL-10 and TNF-alpha genes in Finnish nonagenarians
-
Wang, X. Y., Hurme, M., Jylha, M. & Hervonen, A. (2001) Lack of association between human longevity and polymorphisms of IL-1 cluster, IL-6, IL-10 and TNF-alpha genes in Finnish nonagenarians. Mech Ageing Dev 123, 29-38.
-
(2001)
Mech Ageing Dev
, vol.123
, pp. 29-38
-
-
Wang, X.Y.1
Hurme, M.2
Jylha, M.3
Hervonen, A.4
-
32
-
-
84946650481
-
Probable inference, the law of succession, and statistical inference
-
Wilson, E. B. (1927) Probable inference, the law of succession, and statistical inference. J Am Stat Assoc 22, 209-212.
-
(1927)
J Am Stat Assoc
, vol.22
, pp. 209-212
-
-
Wilson, E.B.1
|