A novel computational strategy for the pKa estimation of drugs by non-linear regression of multiwavelength spectrophotometric pH-titration data exhibiting small spectral changes

Journal of Physical Organic Chemistry

Volumn 20, Issue 9, 2007, Pages 690-701

  Meloun, Milan ^a   Bordovská, Sylva ^a   Syrový, Tomáš ^a  

^a UNIVERSITY OF PARDUBICE   (Czech Republic)

Author keywords

Dissociation constant; Haemanthamine; INDICES; Lisuride; Losartane; MARVIN; PALLAS; Protonation; SPECFIT; Spectrophotometric titration; SQUAD

Indexed keywords

DISSOCIATION; IONIC STRENGTH; PH; PROTONATION; REGRESSION ANALYSIS; SPECTROPHOTOMETRY; TITRATION;

DISSOCIATION CONSTANT; HAEMANTHAMINE; LOSARTANE; SPECTROPHOTOMETRIC TITRATION; STANDARD DEVIATION;

DRUG PRODUCTS;

EID: 34848929016     PISSN: 08943230     EISSN: 10991395     Source Type: Journal    
DOI: 10.1002/poc.1235     Document Type: Article

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