Synthesis and molecular structure of spirocyclic 2-oxindole derivatives of 2-amino-4H-pyran condensed with the pyrazolic nucleus

Tetrahedron

Volumn 63, Issue 46, 2007, Pages 11444-11450

  Redkin, Ruslan Gr ^a   Shemchuk, Leonid A ^a   Chernykh, Valentine P ^a   Shishkin, Oleg V ^b   Shishkina, Svetlana V ^b  

^a NATIONAL UNIVERSITY OF PHARMACY   (Ukraine)

^b INSTITUTE FOR SINGLE CRYSTALS   (Ukraine)

Author keywords

3 Spiro 2 oxindoles; Methylene active nitriles; Michael reaction; Pyrano 2,3 c pyrazol; X ray diffraction analysis

Indexed keywords

2 AMINO 4H PYRAN; 3 METHYLPYRAZOLONE; 4,3' SPIRO[(6 AMINO 3 METHYL 2H,4H PYRANO[2,3 C]PYRAZOLO) 2' OXINDOLE]; ALSTONISINE; GARDMULTINE; ISATIN DERIVATIVE; MACROXIN; MELATONIN; NITRILE; OXINDOLE; PYRAN; PYRAZOLE; SEROTONIN; SPIRO COMPOUND; UNCLASSIFIED DRUG;

ALSTONIA; ANTIMALARIAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CRYSTAL STRUCTURE; DRUG STRUCTURE; DRUG SYNTHESIS; GANGLION BLOCK; KNOEVENAGEL CONDENSATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REPRODUCIBILITY; X RAY DIFFRACTION;

EID: 34848927474     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2007.08.050     Document Type: Article

References (22)

1. Rahman A., Silva W.S.J., Alvi K.A., and De Silva K.T.D. Phytochemistry 26 (1987) 865
2. Rahman A., Qureshi M.M., Muzaffar A., and De Silva K.T.D. Heterocycles 27 (1988) 725
3. Harada M., and Ozaki Y. Chem. Pharm. Bull. 26 (1978) 48
4. Pickering H., Sword S., Vonhoff S., Jones R., and Sugden D. Br. J. Pharmacol. 119 (1996) 379
5. Colotta V., Cecchi L., Catarzi D., Melani F., Filacchioni G., Martini C., Tacchi P., and Lucacchini A. Pharm. Pharmacol. Lett. 2 (1992) 74-76
6. Chem. Abstr. 118 (1993) 32807
7. Joshi K.C., Jain R., and Arora S. J. Indian Chem. Soc. 65 (1988) 277
8. Higashiyama K., and Otomasu H. Chem. Pharm. Bull. 28 (1980) 648
9. Dworczak R., Sterk H., Kratky C., and Junek H. Chem. Ber. 122 (1989) 1323
10. Abdel-Latif F.F., Mashaly M.M., and El-Gawish E.H. J. Chem. Res., Miniprint 5 (1995) 1220
11. Abdelrazek F.M., Metz P., and Farrag E.K. Arch. Pharm. Pharm. Med. Chem. 337 (2004) 482
12. Klokol G.V., Krivolysko S.G., Dyachenko V.D., and Litvinov V.P. Chem. Heterocycl. Compd. (Engl. Transl.) 35 (1999) 1183
13. Khim. Geterotsikl. Soedin. (in Russian) 10 (1999) 1363
14. Dyachenko V.D., and Rusanov Ye.B. Chem. Heterocycl. Compd. (Engl. Transl.) N2 (2004) 270
15. Khim. Geterotsikl. Soedin. (in Russian) (2004) 270
16. Shestopalov A.M., Yakubov A.P., Tsyganov D.V., Yemelyanova Yu.M., and Nesterov V.N. Chem. Heterocycl. Compd. (Engl. Transl.) N10 (2002) 1345
17. Khim. Geterotsikl. Soedin. (in Russian) (2002) 1345
18. Long D.R., Richards C.G., and Ross M.S.F. J. Heterocycl. Chem. 15 (1978) 633
19. Junek H., Dworczak R., Sterk H., and Fabian W. Liebigs Ann. Chem. (1989) 1065
20. Sheldrick G.M. SHELXTL PLUS. PC Version. A System of Computer Programs for the Determination of Crystal Structure from X-ray Diffraction Data (1998), University of Göttingen, Germany
21. Abdel-Latif F.F., Regaila H.A.A., Gohar A.K.M.N., and Mohammed Y.S. Indian J. Chem., Sect. B 24 (1985) 775
22. Daisley R.W., and Walker J. Eur. J. Med. Chem. 14 (1979) 47