Low levels of procalcitonin during episodes of necrotizing enterocolitis

Digestive Diseases and Sciences

Volumn 52, Issue 11, 2007, Pages 2972-2976

  Turner, Dan ^a,b   Hammerman, Cathy ^a   Rudensky, Bernard ^a   Schlesinger, Yechiel ^a   Wine, Eytan ^b   Muise, Aleixo ^b   Schimmel, Michael S ^a  

^a SHAARE ZEDEK MEDICAL CENTER   (Israel)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Etiology; Necrotizing enterocolitis; Preterm infants; Procalcitonin

Indexed keywords

PROCALCITONIN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HORMONE BLOOD LEVEL; HORMONE RELEASE; HUMAN; IMMUNE RESPONSE; INFANT; MALE; NECROTIZING ENTEROCOLITIS; PATHOGENESIS; PRIORITY JOURNAL; SEPSIS;

BIOLOGICAL MARKERS; CALCITONIN; ENTEROCOLITIS, NECROTIZING; FEMALE; FOLLOW-UP STUDIES; GLYCOPROTEINS; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; MALE; PROGNOSIS; PROSPECTIVE STUDIES; PROTEIN PRECURSORS; SEVERITY OF ILLNESS INDEX;

EID: 34848925803     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-007-9763-y     Document Type: Article

References (37)

1. Tudehope DI (2005) The epidemiology and pathogenesis of neonatal necrotizing enterocolitis. J Paediatr Child Health 41:167-168
2. Chan KL, Ng SP, Chan KW, Wo YH, Tam PK (2003) Pathogenesis of neonatal necrotizing enterocolitis: a study of the role of intraluminal pressure, age and bacterial concentration. Pediatr Surg Int 19:573-577
3. Yost CC (2005) Neonatal necrotizing enterocolitis: diagnosis, management, and pathogenesis. J Infus Nurs 28:130-134
4. Luig M, Lui K (2005) Epidemiology of necrotizing enterocolitis. Part II: Risks and susceptibility of premature infants during the surfactant era: a regional study. J Paediatr Child Health 41:174-179
5. Kliegman RM (2005) Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infants. J Pediatr 146:710
6. Santulli TV, Schullinger JN, Heird WC, Gongaware RD, Wigger J, Barlow B, Blanc WA, Berdon WE (1975) Acute necrotizing enterocolitis in infancy: a review of 64 cases. Pediatrics 55:376-387
7. Lawrence G, Bates J, Gaul A (1982) Pathogenesis of neonatal necrotising enterocolitis. Lancet 1:137-139
8. Hsueh W, Caplan MS, Qu XW, Tan XD, De Plaen IG, Gonzalez-Crussi F (2003) Neonatal necrotizing enterocolitis: clinical considerations and pathogenetic concepts. Pediatr Dev Pathol 6:6-23
9. de la Cochetiere MF, Piloquet H, des Robert C, Darmaun D, Galmiche JP, Roze JC (2004) Early intestinal bacterial colonization and necrotizing enterocolitis in premature infants: the putative role of Clostridium. Pediatr Res 56:366-370
10. Hackam DJ, Upperman JS, Grishin A, Ford HR (2005) Disordered enterocyte signaling and intestinal barrier dysfunction in the pathogenesis of necrotizing enterocolitis. Semin Pediatr Surg 14:49-57
11. van Rossum AM, Wulkan RW, Oudesluys-Murphy AM (2004) Procalcitonin as an early marker of infection in neonates and children. Lancet Infect Dis 4:620-630
12. Pecile P, Miorin E, Romanello C, Falleti E, Valent F, Giacomuzzi F, Tenore A (2004) Procalcitonin: a marker of severity of acute pyelonephritis among children. Pediatrics 114:e249-e254
13. Meisner M SJ, Hüttner H, Tschaikowsky K (2004) The natural elimination rate of procalcitonin in patients with normal and impaired renal function. Intensive Care Med 26:P212-P216
14. Turner D, Hammerman C, Rudensky B, Schlesinger Y, Schimmel MS (2006) The role of procalcitonin as a predictor of nosocomial sepsis in preterm infants. Acta Paediatr 95(12):1571 - 1576.
15. Duffy LC, Zielezny MA, Carrion V, Griffiths E, Dryja D, Hilty M, Rook C, Morin F 3rd (1997) Concordance of bacterial cultures with endotoxin and interleukin-6 in necrotizing enterocolitis. Dig Dis Sci 42:359-365
16. Harris MC, Costarino AT Jr, Sullivan JS, Dulkerian S, McCawley L, Corcoran L, Butler S, Kilpatrick L (1994) Cytokine elevations in critically ill infants with sepsis and necrotizing enterocolitis. J Pediatr 124:105-111
17. Grotz MR, Deitch EA, Ding J, Xu D, Huang Q, Regel G (1999) Intestinal cytokine response after gut ischemia: role of gut barrier failure. Ann Surg 229:478-486
18. Ford H, Watkins S, Reblock K, Rowe M (1997) The role of inflammatory cytokines and nitric oxide in the pathogenesis of necrotizing enterocolitis. J Pediatr Surg 32:275-282
19. Turner D, Hammerman C, Rudensky B, Schlesinger Y, Goia C, Schimmel MS (2006) Procalcitonin in preterm infants during the first few days of life: introducing an age related nomogram. Arch Dis Child Fetal Neonatal Ed 91:F283-F286
20. Bell MJ, Ternberg JL, Feigin RD, Keating JP, Marshall R, Barton L, Brotherton T (1978) Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging. Ann Surg 187:1-7
21. Chiesa C, Panero A, Rossi N, Stegagno M, De Giusti M, Osborn JF, Pacifico L (1998) Reliability of procalcitonin concentrations for the diagnosis of sepsis in critically ill neonates. Clin Infect Dis 26:664-672
22. Martin CR, Walker WA (2006) Intestinal immune defences and the inflammatory response in necrotising enterocolitis. Semin Fetal Neonatal Med 11:369-377
23. Bury RG, Tudehope D (2001) Enteral antibiotics for preventing necrotizing enterocolitis in low birthweight or preterm infants. Cochrane Database Syst Rev CD000405
24. Bin-Nun A, Bromiker R, Wilschanski M, Kaplan M, Rudensky B, Caplan M, Hammerman C (2005) Oral probiotics prevent necrotizing enterocolitis in very low birth weight neonates. J Pediatr 147:192-196
25. Lin HC, Su BH, Chen AC, Lin TW, Tsai CH, Yeh TF, Oh W (2005) Oral probiotics reduce the incidence and severity of necrotizing enterocolitis in very low birth weight infants. Pediatrics 115:1-4
26. Ballance WA, Dahms BB, Shenker N, Kliegman RM (1990) Pathology of neonatal necrotizing enterocolitis: a ten-year experience. J Pediatr 117:S6-S13
27. Sun XM, MacKendrick W, Tien J, Huang W, Caplan MS, Hsueh W (1995) Endogenous bacterial toxins are required for the injurious action of platelet-activating factor in rats. Gastroenterology 109:83-88
28. Lee JS, Polin RA (2003) Treatment and prevention of necrotizing enterocolitis. Semin Neonatol 8:449-459
29. Claud EC, Walker WA (2001) Hypothesis: inappropriate colonization of the premature intestine can cause neonatal necrotizing enterocolitis. FASEB J 15:1398-1403
30. Israel EJ (1994) Neonatal necrotizing enterocolitis, a disease of the immature intestinal mucosal barrier. Acta Paediatr Suppl 396:27-32
31. Bush TG (2002) Enteric glial cells. An upstream target for induction of necrotizing enterocolitis and Crohn's disease? Bioessays 24:130-140
32. Habib Z, Arnaud B, Pascal de L, Caroline F, Yves A, Jean-Pierre C, Michel P, Jean-Pierre H, Dominique B (2005) CARD15/NOD2 is not a predisposing factor for necrotizing enterocolitis. Dig Dis Sci 50:1684-1687
33. Szebeni B, Szekeres R, Rusai K, Vannay A, Veres G, Treszl A, Arato A, Tulassay T, Vasarhelyi B (2006) Genetic polymorphisms of CD14, Toll-like receptor 4, and caspase-recruitment domain 15 are not associated with necrotizing enterocolitis in very low birth weight infants. J Pediatr Gastroenterol Nutr 42:27-31
34. Neu J, Chen M, Beierle E (2005) Intestinal innate immunity: How does it relate to the pathogenesis of necrotizing enterocolitis. Semin Pediatr Surg 14:137-144
35. Warner BW, Warner BB (2005) Role of epidermal growth factor in the pathogenesis of neonatal necrotizing enterocolitis. Semin Pediatr Surg 14:175-180
36. Caplan MS, MacKendrick W (1994) Inflammatory mediators and intestinal injury. Clin Perinatol 21:235-246
37. Caplan MS, Sun XM, Hseuh W, Hageman JR (1990) Role of platelet activating factor and tumor necrosis factor-alpha in neonatal necrotizing enterocolitis. J Pediatr 116:960-964