Myostatin promoter analysis and expression pattern in pigs

Livestock Science

Volumn 112, Issue 1-2, 2007, Pages 143-150

  Guimaraes, Simone E F ^a,b   Stahl, Chad H ^a   Lonergan, Steven M ^a   Geiger, Becky ^c   Rothschild, Max F ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b FEDERAL UNIVERSITY OF VIÇOSA   (Brazil)

^c GENUS PLC   (United States)

Author keywords

Myogenesis; Pig production; Semi quantitative RT PCR

Indexed keywords

BOS; SUIDAE;

EID: 34848916404     PISSN: 18711413     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.livsci.2007.02.004     Document Type: Article

References (14)

1. Cieslak D., Blicharski T., Kapelanski W., and Pierzchala M. Investigation of polymorphisms in the porcine Myostatin (GDF8; MSTN) gene. Czech J. Anim. Sci. 48 (2003) 69-75
2. Grobet L., Martin L.J., Poncelet D., Pirottin D., Brouwers B., Riquet J., Schoeberlein A., Dunner S., Menissier F., Massabanda J., Fries R., Hanset R., and Georges M. A deletion in the bovine Myostatin gene causes the double-muscled phenotype in cattle. Nat. Genet. 17 (1997) 71-74
3. Grobet L., Poncelet D., Royo L.J., Brouwers B., Pirottin D., Michaux C., Menissier F., Zanotti M., Dunner S., and Georges M. Molecular definition of an allelic series of mutations disrupting the Myostatin function and causing double-muscling in cattle. Mamm. Genome 9 (1998) 210-213
4. Hidaka K., Yamamoto I., Arai Y., and Mukai T. The MEF-3 motif is required for MEF-2 mediated skeletal muscle-specific induction of the rat aldolase A gene. Molec. Cell Biol. 13 (1993) 6469-6478
5. Ji S., Losinski R.L., Cornelius S.G., Frank G.R., Willis G.M., Gerrard D.E., Depreux F.F., and Spurlock M.E. Myostatin expression in porcine tissues: tissue specificity and developmental and postnatal regulation. Am. J. Physiol. 275 (1998) R1265-R1273
6. Jiang Y.L., Li N., Plastow G., Liu Z.L., Hu X.X., and Wu C.X. Identification of three SNPs in the porcine Myostatin gene (MSTN). Anim. Biotechnol. 13 (2002) 173-178
7. Kim H.S., Liang L., Dean R.G., Hausman D.B., Hartzell D.L., and Baile C.A. Inhibition of preadipocyte differentiation by Myostatin treatment in 3t3-11 cultures. Biochem. Biophys. Res. Commun. 281 (2001) 902-906
8. T method. Methods 25 (2001) 402-408
9. McPherron A.C., Lawler A.M., and Lee S.J. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 387 (1997) 83-90
10. Spiller M.P., Kambadur R., Jeanplong F., Thomas M., Martyn J.K., Bass J.J., and Sharma M. The Myostatin gene is a downstream target of basic helix-loop-helis transcription factor MyoD. Molec. Cell Biol. 22 (2002) 7066-7082
11. Stinckens A., Bijttebier J., Luyten T., Van Den Maagdenberg K., Harmegnies N., De Smet S., Georges M., and Buys N. Detection of polymorphisms in the Myostatin gene in Belgian Pietrain pigs. Commun. Appl. Biol. Sci. 70 (2005) 37-41
12. Stratil A., and Kopecny M. Genomic organization, sequence and polymorphism of the porcine Myostatin (GDF8; MSTN) gene. Anim. Genet. 30 (1999) 468-470
13. Tellgren A., Berglund A., Savolainen P., Janis A.M., and Liberles D.A. Myostatin rapid sequence evolution in ruminants predates domestication. Mol. Phylogenet. Evol. 33 (2004) 782-790
14. Thomas M., Langley C., Berry C., Sharma M., Kirk S., Bass J., and Kambadur R. Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation. J. Biol. Chem. 275 (2000) 40235-40243