High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: Insights into the mechanism and specificity of this novel prokaryotic enzyme

Journal of Biological Chemistry

Volumn 282, Issue 37, 2007, Pages 27334-27342

  Reddy, Manchi C M ^a   Palaninathan, Satheesh K ^a   Shetty, Nishant D ^a   Owen, Joshua L ^a   Watson, Misty D ^a   Sacchettini, James C ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CHARACTERIZATION; CONFORMATIONS; CRYSTAL STRUCTURE; PHOSPHORYLATION; SUBSTRATES;

ADENOSINE MONOPHOSPHATE (AMP); BINARY COMPLEXES; MYCOBACTERIUM TUBERCULOSIS; NUCLEOSIDES;

ENZYME ACTIVITY;

2 FLUOROADENOSINE; ADENOSINE KINASE; ADENOSINE TRIPHOSPHATE DERIVATIVE; BETA,GAMMA METHYLENEADENOSINE TRIPHOSPHATE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN INTERACTION;

ADENOSINE KINASE; BINDING SITES; CRYSTALLIZATION; DIMERIZATION; ESCHERICHIA COLI; HUMANS; MYCOBACTERIUM TUBERCULOSIS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN STRUCTURE, SECONDARY;

EUKARYOTA; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; PROKARYOTA;

EID: 34848907756     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M703290200     Document Type: Article

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