Site-directed mutagenesis studies to probe the role of specific residues in the external loop (L3) of OmpF and OmpC porins in susceptibility of Serratia marcescens to antibiotics

Canadian Journal of Microbiology

Volumn 53, Issue 6, 2007, Pages 710-719

  Begic, Sanela ^a   Worobec, Elizabeth A ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Antibiotic resistance; Porins; Serratia marcescens; Site directed mutagenesis

Indexed keywords

AMINO ACIDS; ANTIBIOTICS; BIOASSAY; CONCENTRATION (PROCESS); MUTAGENESIS; PATIENT TREATMENT; PROTEINS;

ANTIBIOTIC RESISTANCE; ASPARTIC ACIDS; ENTEROBACTERIACEAE; PORINS; SERRATIA MARCESCENS;

BACTERIA;

AMPICILLIN; ASPARTIC ACID; CARBENICILLIN; CEFALORIDINE; CEFALOTIN; CIPROFLOXACIN; NORFLOXACIN; OFLOXACIN; OUTER MEMBRANE PROTEIN C; OUTER MEMBRANE PROTEIN F;

ANTIBIOTIC RESISTANCE; BACTERIUM; CONCENTRATION (COMPOSITION); MEMBRANE; MUTATION; PERMEABILITY; PROTEIN;

AIRLIFT REACTOR; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DRUG SENSITIVITY; ENTEROBACTERIACEAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; SERRATIA MARCESCENS; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; FLUOROQUINOLONES; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC COMPLEMENTATION TEST; LIPOSOMES; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PORINS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SERRATIA MARCESCENS;

BACTERIA (MICROORGANISMS); ENTEROBACTERIACEAE; SERRATIA MARCESCENS;

EID: 34848896064     PISSN: 00084166     EISSN: None     Source Type: Journal    
DOI: 10.1139/W07-018     Document Type: Article

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