Prediction of type 1 diabetes among siblings of affected children and in the general population

Diabetologia

Volumn 50, Issue 11, 2007, Pages 2272-2275

  Siljander, H T ^a,b   Veijola, R ^c   Reunanen, A ^d   Virtanen, S M ^b,d,e   Akerblom H K ^a   Knip, M ^a,b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF OULU   (Finland)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^e UNIVERSITY OF TAMPERE   (Finland)

Author keywords

Autoantibodies; General population; Prediction; Siblings; Type 1 diabetes

Indexed keywords

AUTOANTIBODY; GADA ANTIBODY; IA 2A ANTIBODY; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CHILD; COHORT ANALYSIS; FEMALE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PRIORITY JOURNAL; RISK FACTOR; SCREENING TEST; SIBLING;

ADOLESCENT; AUTOANTIBODIES; CHILD; DIABETES MELLITUS, TYPE 1; FINLAND; FOLLOW-UP STUDIES; HUMANS; MASS SCREENING; PREDICTIVE VALUE OF TESTS; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 8; REFERENCE VALUES; RISK FACTORS; SIBLINGS;

EID: 34848878979     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-007-0799-5     Document Type: Article

References (12)

1. Pietropaolo M, Yu S, Libman IM et al (2005) Cytoplasmic islet cell antibodies remain valuable in defining risk of progression to type 1 diabetes in subjects with other islet autoantibodies. Pediatr Diabetes 5:184-192
2. Dittler J, Seidel D, Schenker M, Ziegler AG (1998) GADIA2-combi determination as first-line screening for improved prediction of type 1 diabetes in relatives. Diabetes 47:592-597
3. Bingley PJ, Bonifacio E, Ziegler AG, Schatz DA, Atkinson MA, Eisenbarth GS (2001) Proposed guidelines on screening for risk of type 1 diabetes. Diabetes Care 24:398
4. LaGasse JM, Brantley MS, Leech NJ et al (2002) Successful prospective prediction of type 1 diabetes in schoolchildren through multiple defined autoantibodies: an 8-year follow-up of the Washington State Diabetes Prediction Study. Diabetes Care 25:505-511
5. Schlosser M, Strebelow M, Wassmuth R et al (2002) The Karlsburg type 1 diabetes risk study of a normal schoolchild population: association of beta-cell autoantibodies and human leukocyte antigen-DQB1 alleles in antibody-positive individuals. J Clin Endocrinol Metab 87:2254-2261
6. Kulmala P, Savola K, Petersen JS et al (1998) Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study. The Childhood Diabetes in Finland Study Group. J Clin Invest 101:327-336
7. Åkerblom HK, Viikari J, Raitakari OT, Uhari M (1999) Cardiovascular risk in Young Finns Study: general outline and recent developments. Ann Med 31(Suppl 1):45-54
8. World Health Organization (1999) Definition, diagnosis and classification of diabetes mellitus and its complications: Report of a WHO consultation. WHO, Geneva (WHO/NCD/NCS 99.2)
9. Tuomilehto J, Virtala E, Karvonen M et al (1995) Increase in incidence of insulin-dependent diabetes mellitus among children in Finland. Int J Epidemiol 24:984-992
10. Savola K, Sabbah E, Kulmala P, Vähäsalo P, Ilonen J, Knip M (1998) Autoantibodies associated with type I diabetes mellitus persist after diagnosis in children. Diabetologia 41:1293-1297
11. Maclaren NK, Lan MS, Schatz D, Malone J, Notkins AL, Krischer J (2003) Multiple autoantibodies as predictors of type 1 diabetes in a general population. Diabetologia 46:873-874
12. Veijola R, Reijonen H, Vähäsalo P et al (1996) HLA-DQB1-defined genetic susceptibility, beta cell autoimmunity, and metabolic characteristics in familial and nonfamilial insulin-dependent diabetes mellitus. Childhood Diabetes in Finland (DiMe) Study Group. J Clin Invest 98:2489-2495