Dystroglycan expression is reduced during prostate tumorigenesis and is regulated by androgens in prostate cancer cells

Journal of Cellular Physiology

Volumn 213, Issue 2, 2007, Pages 528-539

  Sgambato, A ^a,b   De Paola, B ^b   Migaldi, M ^c   Di Salvatore, M ^b   Rettino, A ^b   Rossi, G ^c   Faraglia, B ^b   Boninsegna, A ^b   Maiorana, A ^c   Cittadini, A ^a,b  

^a REFERRAL CANCER CENTER OF BASILICATA   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA DYSTROGLYCAN; ANDROGEN; BETA DYSTROGLYCAN; COMPLEMENTARY DNA; DYSTROGLYCAN;

ADULT; AGED; ANCHORAGE INDEPENDENT GROWTH; ARTICLE; CELL ADHESION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION REGULATION; HORMONAL REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION;

ADULT; AGED; AGED, 80 AND OVER; ANDROGEN ANTAGONISTS; ANDROGENS; CELL LINE, TUMOR; DYSTROGLYCANS; ELECTRIC IMPEDANCE; FLUTAMIDE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KAPLAN-MEIERS ESTIMATE; MALE; MIDDLE AGED; PROGNOSIS; PROSTATIC NEOPLASMS; PROTEIN SUBUNITS; TUMOR MARKERS, BIOLOGICAL;

EID: 34848877468     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21130     Document Type: Article

References (53)

1. AJCC. 2002. AJCC American Joint Committee on Cancer Staging Manual. New York, USA: Springer-Verlag.
2. Brennan P, Jing J, Ethunandan M, Gorecki D. 2004. Dystroglycan complex in cancer. Eur J Surg Oncol 30:589-592.
3. Calogero A, Pavoni E, Gramaglia T, D'Amati G, Ragona G, Brancaccio A, Petrucci T. 2006. Altered exression of a-dystroglycan subunit in human gliomas. Cancer Biol Ther 5:441-448.
4. Cavaldesi M, Macchia G, Barca S, Defilippi P, Tarone G, Petrucci TC. 1999. Association of the dystroglycan complex isolated from bovine brain synaptosomes with proteins involved in signal transduction. J. Neurochem 72:1648-1655.
5. Chardin P, Cussac D, Maignan S, Ducruix A. 1995. The Grb2 adaptor. FEBS Lett 369:47-51.
6. Chockalingam PS, Cholera R, Oak SA, Zheng Y, Jarrett HW, Thomason DB 2002. Dystrophin-glycoprotein complex and Ras and Rho GTPase signaling are altered in muscle atrophy. Am J Physiol Cell Physiol 283:500-511.
7. Driss A, Charrier L, Yan Y, Nduati V, Sitaraman S, Merlin D. 2006. Dystroglycan receptor is involved in integrin activation in intestinal epithelia. Am J Physiol Gastrointest Liver Physiol 290:G1228-G1242.
8. Durbeej M, Campbell KP. 1998. Biochemical characterization of the epithelial dystroglycan complex. J Biol Chem 274:26609-26616.
9. Durbeej M, Henry MD, Ferletta M, Campbell KP, Ekblom P. 1998. Distribution of dystroglycan in normal adult mouse tissues. J Histochem Cytochem 46:449-457.
10. Durbeej M, Larsson E, Ibraghimov-Beskrovnaya O, Roberds SL, Campbell KP, Ekblom P. 1995. Non-muscle β-dystroglycan is involved in epithelial development. J Cell Biol 130:79-91.
11. Durbeej M, Talts JF, Henry MD, Yurchenco PD, Campbell KP, Ekblom P. 2001. Dystroglycan binding to laminin αILG4 module influences epithelial morphogenesis of salivary gland and lung in vitro. Differentiation 69:121-134.
12. Epstein J, Allsbrook WJ, Amin M, Egevad L, Committee IG. 2005. The 2005 International Society of Urological Pathology ISUP Consensus Conference on Gleason Grading of Prostatic Carcinoma. Am J Surg Pathol 29:1228-1242.
13. Ervasti JM, Campbell KP. 1996. Dystroglycan: An extracellular matrix receptor linked to the cytoskeleton. Curr Opin Cell Biol 8:625-631.
14. Esapa CT, Bentham GR, Schroder JE, Kroger S, Blake DJ. 2003. The effects of post-translational processing on dystroglycan synthesis and trafficking. FEBS Lett 555:209-216.
15. Giaever I, Keese C. 1984. Monitoring fibroblast behavior in tissue culture with an applied electric field. Proc Natl Acad Sci USA 81:3761-3764.
16. Giaever I, Keese C. 1993. A morphological biosensor for mammalian cells. Nature 366:591-592.
17. Henry MD, Campbell KP. 1998. A role for dystroglycan in basement membrane assembly. Cell 95:859-870.
18. Henry MD, Campbell KP. 1999. Dystroglycan inside and out. Curr Opin Cell Biol 11:602-607.
19. Henry MD, Cohen MB, Campbell KP. 2001. Reduced expression of dystroglycan in breast and prostate cancer. Hum Pathol 32:791-795.
20. Herzog C, Has C, Franzke C-W, Echtermeyer F, Schlotzer-Schrehardt U, Kroger S, Gustafsson E, Fassler R, Bruckner-Tuderman L. 2004. Dystroglycan in skin and cutaneous cells: β-subunit is shed from the cell surface. J Invest Dermatol 122:1372-1380.
21. Holt KH, Crosbie RH, Venzke DP, Campbell KP. 2000. Biosynthesis of dystroglycan: Processing of a precursor peptide. FEBS Lett 468:79-83.
22. Holzbeierlein J. 2004. Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance. Am J Pathol 164:217-227.
23. Ibraghimov-Beskrovnaya O, Ervasti JM, Leveille CJ, Slaughter CA, Sernett SW, Campbell KP. 1992. Primary structure of dystroph in-associated glycoproteins linking dystrophin to the extracellular matrix. Nature 355:696-702.
24. Ibraghimov-Beskrovnaya O, Mialtovich A, Ozcelik T, Yang B, Koepnick K, Francke U, Campbell KP. 1993. Human dystroglycan: Skeletal muscle cDNA, genomic structure, origin of tissue specific isoforms and chromosomal localization. Hum Mol Gen 2:1651-1657.
25. Jing J, Lien CF, Sharma S, Rice J, Brennan PA, Gorecki DC. 2004. Aberrant expression, processing and degradation of dystroglycan in squamous cell carcinomas. Eur J Cancer 40:2143-2151.
26. Kadar A, Tokes AM, Kulka J, Robert L. 2002. Extracellular matrix components in breast carcinomas. Semin Cancer Biol 12:243-257.
27. Kahl J, Campanelli J. 2003. A Role for the juxtamembrane domain of dystroglycan in agrin-induced acetylcholine receptor clustering. J Neurosci 23:392-402.
28. Kanagawa M, Saito F, Kunz S, Yoshida-Moriguchi T, Barresi R, Kobayashi YM, Muschler J, Dumanski JP, Michele DE, Oldstone MB, Campbell KP 2004. Molecular recognition by LARGE is essential for expression of functional dystroglycan. Cell 117:953-964.
29. Langenbach KJ, Rando TA. 2002. Inhibition of dystroglycan binding to laminin disrupts the PI3K/AKT pathway and survival signaling in muscle cells. Muscle Nerve 26:644-653.
30. Lin CQ, Bissell MJ. 1993. Multi-faceted regulation of cell differentiation by extracellular matrix. FASEB J 7:737-743.
31. Losasso C, Di Tommaso F, Sgambato A, Ardito R, Cittadini A, Giardina B, Petrucci TC, Brancaccio A. 2000. Anomalous dystroglycan in carcinoma cell lines. FEBS Lett 484:194-198.
32. Mitra P, Keese C, Giaever I. 1991. Electric measurements can be used to monitor the attachment and spreading of cells in tissue culture. Biotechniques 11:504-510.
33. Mousses S. 2001 Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling. Oncogene 20:6718-6723.
34. Muschler J, Levy D, Boudreau R, Henry M, Campbell K, Bissell MJ. 2002. A role for dystroglycan in epithelial polarization: Loss of function in breast tumor cells. Cancer Res 62:7102-7109
35. Raz A. 2004. Dystroglycan: To adhere or not adhere during cancer progression. Cancer Biol Ther 3:976-976.
36. Ross J, Jennings T, Nazeer T, Sheehan C, Fisher H, Kauffman R, Anwar S, Kallakury B. 2003. Prognostic factors in prostate cancer. Am J Clin Pathol 120:S85-S100.
37. Ruoslahti E. 1992. Control of cell motility and tumour invasion by extracellular matrix interactions. Br J Cancer 66:239-242.
38. Russo K, Di Stasio E, Macchia G, Rosa G, Brancaccio A, Petrucci TC. 2000. Characterization of the beta-dystroglycan-growth factor receptor 2 Grb2 interaction. Biochem Biophys Res Commun 274:93-98.
39. Sgambato A, Brancaccio A. 2005. The dystroglycan complex: From biology to cancer. J Cell Physiol 205:163-169.
40. Sgambato A, Camerini A, Montanari M, Camerini A, Brancaccio A, Spada D, Cangiano R, Losasso C, Capelli G, Trentini G, Cittadini A. 2004. Increased expression of dystroglycan inhibits the growth and tumorigenicity of human mammary epithelial cells. Cancer Biol Ther 3:849-860.
41. Sgambato A, Di Salvatore M, De Paola B, Rettino A, Faraglia B, Boninsegna A, Graziani C, Camerini A, Proietti G, Cittadini A. 2006a. Analysis of dystroglycan regulation and functions in mouse mammary epithelial cells and implications for mammary tumorigenesis. J Cell Physiol 207:520-529.
42. Sgambato A, Migaldi M, Montanari M, Camerini A, Brancaccio A, Rossi G, Cangiano R, Losasso C, Capelli G, Trentini GP, Cittadini A. 2003. Dystroglycan expression is frequently reduced in human breast and colon cancers and is associated with tumor progression. Am J Pathol 162:849-860.
43. Sgambato A, Tarquini E, Resci F, De Paola B, Faraglia B, Camerini A, Rettino A, Migaldi M, Cittadini A, Zannoni G. 2006b. Aberrant expression of alpha-dystroglycan in cervical and vulvar cancer. Gynecol Oncol [Epub ahead of print].
44. Singh J, Itahana Y, Knight-Krajewski S, Kanagawa M, Campbell KP, Bissell MJ, Muschler J. 2004. Proteolytic enzymes and altered glycosylation modulate dystroglycan function in carcinoma cells. Cancer Res 64:6152-6159.
45. Spence HJ, Dhillon AS, James M, Winder SJ. 2004. Dystroglycan, a scaffold for the ERK-MAP kinase cascade. EMBO Rep 5:1-6.
46. Tremblay M, Carbonetto S. 2006. An extracellular pathway for dystroglycan function in acetylcholine receptor aggregation and laminin deposition in skeletal myotubes. J Biol Chem 281:13365-13373.
47. Wegener J, Keese C, Giaever I. 2000. Electric cell-substrate impedance sensing ECIS as a noninvasive means to monitor the kinetics of cell spreading to artificial surfaces. Exp Cell Res 259:158-166.
48. Weir M, Muschler J. 2003. Dystroglycan: Emerging roles in mammary gland function. J Mammary Gland Biol Neopl 8:409-419.
49. Williamson RA, Henry MD, Daniels KJ, Hrstka RF, Lee JC, Sunada Y, Ibraghimov-Beskrovnaya O, Campbell KP 1997. Dystroglycan is essential for early embryonic development: Disruption of Reichert's membrane in Dag1-null mice. Hum Mol Genet 6:831-841.
50. Winder SJ. 2001. The complexities of dystroglycan. TIBS 26:118-124.
51. Yamada H, Saito F, Fukuta-Ohi H, Zhong D, Hase A, Arai K, Okuyama A, Maekawa R, Shimizu T, Matsumura K. 2001. Processing of β-dystroglycan by matrix metalloproteinase disrupts the link between the extracellular matrix and cell membrane via the dystroglycan complex. Hum Mol Genet 10:1563-1569.
52. Yang B, Jung D, Motto D, Meyeer J, Koretzky G, Campbell KP. 1995. SH3 domain mediated interaction of dystroglycan and Grb2. J Biol Chem 270:11711-11714.
53. Zhu Y-S, Cai L-Q, You X, Cordero J, Huang Y, Imperato-Mcginley J. 2003. Androgen-induced prostate-specific antigen gene expression is mediated via dihydrotestosterone in LNCaP cells. J Androl 24:681-687.