Are false-positive phencyclidine immunoassay instant-view multi-test results caused by overdose concentrations of ibuprofen, metamizol, and dextromethorphan? [1]

Therapeutic Drug Monitoring

Volumn 29, Issue 5, 2007, Pages 671-673

  Marchei, Emilia ^a   Pellegrini, Manuela ^a   Pichini, Simona ^a   Martín, Itziar ^b   García Algar, Óscar ^b,c   Vall, Oriol ^b,c  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b HOSPITAL DEL MAR   (Spain)

^c UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYIBUPROFEN; 4 AMINOPHENAZONE; 4 FORMYLAMINOANTIPYRINE; CARBOXYIBUPROFEN; DEXTROMETHORPHAN; DIPYRONE; DRUG METABOLITE; IBUPROFEN; NORAMIDOPYRINE; PHENCYCLIDINE; UNCLASSIFIED DRUG;

APGAR SCORE; APNEA; ATAXIA; BLOOD CHEMISTRY; CASE REPORT; DRUG IDENTIFICATION; DRUG SCREENING; DRUG URINE LEVEL; FALSE POSITIVE RESULT; FEMALE; GAS CHROMATOGRAPHY; GRAND MAL SEIZURE; HUMAN; HYPOGLYCEMIA; IMMUNOASSAY; LETTER; LIQUID LIQUID EXTRACTION; MALE; MASS SPECTROMETRY; MUSCLE HYPOTONIA; NEWBORN; OTALGIA; PHYSICAL EXAMINATION; PRESCHOOL CHILD; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEROLOGY; TOXICITY TESTING; URINALYSIS;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTITUSSIVE AGENTS; CHILD, PRESCHOOL; DEXTROMETHORPHAN; DIAGNOSIS, DIFFERENTIAL; DIPYRONE; FALSE POSITIVE REACTIONS; FEMALE; HUMANS; IBUPROFEN; IMMUNOASSAY; INFANT, NEWBORN; MALE; OVERDOSE; PHENCYCLIDINE; SEIZURES;

EID: 34848869719     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/FTD.0b013e318156e983     Document Type: Letter

References (12)

1. Maurer HH, Arlt JW, Kraemer T, et al. Analytical development for low molecular weight xenobiotic compounds. Arch Toxicol Suppl. 1997;19:189-197.
2. Oliveira ARM, Santana FJM, Bonato PS. Stereoselective determination of the major ibuprofen metabolites in human urine by off-line coupling solid-phase microextraction and high-performance liquid chromatography. Anal Chim Acta. 2005;538:25-34.
3. Peace MR, Tarnai LD, Poklis A. Performance evaluation of four on-site drug-testing devices for detection of drugs of abuse in urine. J Anal Toxicol. 2000;24:589-594.
4. Mussig K, Pfafflin A, Haring HU, et al. Dipyrone (metamizol) metabolites interfere with HPLC analysis of plasma catecholamines but not with the determination of urinary catecholamines. Clin Chem. 2006;52:1829-1831.
5. Smardi G, Jamali F. Pharmacokinetics of dipyrone inman: role of the administration route. Eur J Drug Metab Pharmacokinet. 1985;10:121-125.
6. Levy M, Zylber-Katz E, Rosenkranz B. Clinical pharmacokinetics of dipyrone and its metabolites. Clin Pharmacokinet. 1995;28:216-234.
7. Schwartz RH. Adolescent abuse of dextromethorphan. Clin Pediatr (Phila). 2005;44:565-568.
8. Kim EM, Lee JS, Park MJ, et al. Standardization of method for the analysis of dextromethorphan in urine. Forensic Sci Int. 2006;161:198-201.
9. Miller J, Valdes R Jr. Methods for calculating cross-reactivity in immunoassays. J Clin Immunoassay. 1992;15:97-107.
10. Way BA, Wilhite TR, Smith CH, et al. Measurement of plasma ibuprofen by gas chromatography-mass spectrometry. J Clin Lab Anal. 1997;11:336-339.
11. Degiovanni N, d'Aloja E. Death due to baclofen and dipyrone ingestion. Forensic Sci Int. 2001:123:26-32.
12. Wood DM, Monaghan J, Streete P, et al. Fatality after deliberate ingestion of sustained-release ibuprofen: a case report. Crit Care. 2006:10:R44.