Seminal plug expulsion induced by electrical stimulation of the intermesenteric nerve in anesthetized rats

Biology of Reproduction

Volumn 77, Issue 4, 2007, Pages 717-722

  Bernabé, Jacques ^a   Clément, Pierre ^a   Denys, Pierre ^b,c   Alexandre, Laurent ^a   Giuliano, François ^a,b,c  

^a CNRS   (France)

^b RAYMOND POINCARÉ HOSPITAL   (France)

^c LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

Author keywords

Bulbospongiosus muscle; Central nervous system; Ejaculation; Intermesenteric nerve; Male sexual function; Rat; Seminal vesicles

Indexed keywords

ISOFLURANE;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTONOMIC NERVE; AUTONOMIC NERVOUS SYSTEM; BLADDER NECK; BULBOSPONGIOSUS MUSCLE; EJACULATION; ELECTROSTIMULATION; INTERMESENTERIC NERVE; MALE; MUSCLE CONTRACTION; NERVE STIMULATION; NONHUMAN; PELVIS; PERINEUM; PRIORITY JOURNAL; RAT; SEMINAL VESICLE; SENSORY NERVE; SKELETAL MUSCLE;

ANESTHESIA; ANIMALS; EJACULATION; ELECTRIC STIMULATION; MALE; MESENTERY; MUSCLE CONTRACTION; PERIPHERAL NERVES; RATS; RATS, INBRED STRAINS; SEMINAL VESICLES;

RATTUS;

EID: 34848864256     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.107.060921     Document Type: Article

References (26)

1. Bohlen D, Hugonnet CL, Mills RD, Weise ES, Schmid HP. Five meters of H(2)O: the pressure at the urinary bladder neck during human ejaculation. Prostate 2000; 44:339-341.
2. Gil-Vernet JM Jr, Alvarez-Vijande R, Gil-Vernet A, Gil-Vernet JM. Ejaculation in men: a dynamic endorectal ultrasonographical study. Br J Urol 1994; 73:442-448.
3. Gerstenberg TC, Levin RJ, Wagner G. Erection and ejaculation in man. Assessment of the electromyographic activity of the bulbocavernosus and ischiocavernosus muscles. Br J Urol 1990; 65:395-402.
4. Dail WG. Autonomic innervation of male genitalia. In: Maggi CA (ed.), Nervous Control of the Urogenital System. Chur, Switzerland: Harwood Academic; 1993:69-102.
5. Janig W, McLachlan EM. Organization of lumbar spinal outflow to distal colon and pelvic organs. Physiol Rev 1987; 67:1332-1404.
6. Owman C, Stjernquist M. The peripheral nervous system. In: Bjorklund A, Hokfelt T, Owman C (eds.), Handbook of Chemical Neuroanatomy. Amsterdam: Elsevier Science; 1988:445-544.
7. Giuliano F, Facchinetti P, Bernabé J, Benoit G, Calas A, Rampin O. Evidence of sympathetic fibers in the male rat pelvic nerve by gross anatomy, retrograde labelling and high resolution autoradiographic study. Int J Impot Res 1997; 9:179-185.
8. Johnson RD, Halata Z. Topography and ultrastructure of sensory nerve endings in the glans penis of the rat. J Comp Neurol 1991; 312:299-310.
9. Nunez R, Gross GH, Sachs BD. Origin and central projections of rat dorsal penile nerve: possible direct projection to autonomic and somatic neurons by primary afferents of nonmuscle origin. J Comp Neurol 1986; 247:417-429.
10. Baron R, Janig W. Afferent and sympathetic neurons projecting into lumbar visceral nerves of the male rat. J Comp Neurol 1991; 314:429-436.
11. Johnson RD, Hubscher CH. Brainstem microstimulation differentially inhibits pudendal motoneuron reflex inputs. Neuroreport 1998; 9:341-345.
12. McKenna KE, Chung SK, McVary KT. A model for the study of sexual function in anesthetized male and female rats. Am J Physiol 1991; 261:R1276-1285.
13. Nordling J, Andersen JT, Walter S, Meyhoff HH, Hald T, Gammelgaard PA. Evoked response of the bulbocavemosus reflex. Eur Urol 1979; 5:36-38.
14. Opsomer RJ, Caramia MD, Zarola F, Pesce F, Rossini PM. Neurophysiological evaluation of central-peripheral sensory and motor pudendal fiber. Electroencephalogr Clin Neurophysiol 1989; 74:260-270.
15. Hsieh JT, Chang HC, Law HS, Hsieh CH, Cheng JT. In vivo evaluation of serotonergic agents and alpha-adrenergic blockers on premature ejaculation by inhibiting the seminal vesicle pressure response to electrical nerve stimulation. Br J Urol 1998; 82:237-240.
16. Kihara K, De Groat WC. Sympathetic efferent pathways projecting to the bladder neck and proximal urethra in the rat. J Auton Nerv Syst 1997; 62:134-142.
17. Turek PJ, Aslam K, Younes AK, Nguyen HT. Observations on seminal vesicle dynamics in an in vivo rat model. J Urol 1998; 159:1731-1734.
18. Luckensmeyer GB, Keast JR. Distribution and morphological characterization of viscerofugal projections from the large intestine to the inferior mesenteric and pelvic ganglia of the male rat. Neuroscience 1995; 66:663-671.
19. Schroder HD. Anatomical and pathoanatomical studies on the spinal efferent systems innervating pelvic structures. 1. Organization of spinal nuclei in animals. 2. The nucleus X-pelvic motor system in man. J Auton Nerv Syst 1985; 14:23-48.
20. Xu C, Giuliano F, Yaici ED, Conrath M, Trassard O, Benoit G, Verge D. Identification of lumbar spinal neurons controlling simultaneously the prostate and the bulbospongiosus muscles in the rat. Neuroscience 2006; 138:561-573.
21. McKenna KE, Nadelhaft I. The pudendo-pudendal reflex in male and female rats. J Auton Nerv Syst 1989; 27:67-77.
22. Carro-Juarez M, Cruz SL, Rodriguez-Manzo G. Evidence for the involvement of a spinal pattern generator in the control of the genital motor pattern of ejaculation. Brain Res 2003; 975:222-228.
23. Brindley GS, Sauerwein D, Hendry WF. Hypogastric plexus stimulators for obtaining semen from paraplegic men. Br J Urol 1989; 64:72-77.
24. Wieder JA, Brackett NL, Lynne CM, Green JT, Aballa TC. Anesthetic block of the dorsal penile nerve inhibits vibratory-induced ejaculation in men with spinal cord injuries. Urology 2000; 55:915-917.
25. Martin DC, Adams RJ, Aronstam RS. The influence of isoflurane on the synaptic activity of 5-hydroxytryptamine. Neurochem Res 1990; 15:969-973.
26. Giuliano F. 5-Hydroxytryptamine in premature ejaculation: opportunities for therapeutic intervention. Trends Neurosci 2006; 30:79-84.