Synthesis and antitussive evaluation of verticinone-cholic acid salt, a novel and potential cough therapeutic agent

Acta Pharmacologica Sinica

Volumn 28, Issue 10, 2007, Pages 1591-1596

  Xu, Fang Zhou ^a,b   Chen, Chang ^a   Zhang, Yong Hui ^a   Ruan, Han Li ^a   Pi, Hui Fang ^a   Zhang, Pong ^a   Wu, Ji Zhou ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b PEKING UNIVERSITY SHENZHEN HOSPITAL   (China)

Author keywords

Antitussive effect; ATP sensitive K+ channels; Cholic acid; Shedan Chuanbei powder; Verticinone; Verticinone cholic acid salt

Indexed keywords

ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ANTITUSSIVE AGENT; CHOLIC ACID; CITRIC ACID; GLIBENCLAMIDE; HERBACEOUS AGENT; NALOXONE; POTASSIUM CHANNEL BLOCKING AGENT; SHEDAN CHUANBEI; UNCLASSIFIED DRUG; VERTICINONE; VERTICINONE CHOLIC ACID;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTITUSSIVE ACTIVITY; ARTICLE; CHINESE MEDICINE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG FORMULATION; DRUG POTENTIATION; DRUG SCREENING; DRUG SYNTHESIS; NONHUMAN; POWDER; SINGLE DRUG DOSE;

ANIMALS; ANTITUSSIVE AGENTS; CEVANES; CHOLIC ACID; COUGH; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMPOUNDING; FEMALE; GLYBURIDE; GUINEA PIGS; KATP CHANNELS; MALE; MICE; MOLECULAR STRUCTURE; NALOXONE; RANDOM ALLOCATION; RECEPTORS, OPIOID;

EID: 34848860749     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2007.00179.x     Document Type: Article

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