Simultaneous determination of fixed dose combination of nebivolol and valsartan in human plasma by liquid chromatographic-tandem mass spectrometry and its application to pharmacokinetic study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 858, Issue 1-2, 2007, Pages 143-150

  Selvan, P Senthamil ^a   Gowda, K Veeran ^a   Mandal, U ^a   Solomon, W D Sam ^a   Pal, T K ^a  

^a JADAVPUR UNIVERSITY   (India)

Author keywords

LC API MS MS; Nebivolol; Valsartan

Indexed keywords

FIXED DOSE COMBINATION (FDC); INTERNAL STANDARD (IS); SELECTED REACTION MONITORING MODE (SRM); VALSARTAN FORMULATION;

ACETONITRILE; ATMOSPHERIC PRESSURE; FORMIC ACID; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; PLASMA (HUMAN);

DRUG DOSAGE;

FORMIC ACID; NEBICARD; NEBIVOLOL; UNCLASSIFIED DRUG; VALSARTAN;

ADULT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG FORMULATION; DRUG HALF LIFE; DRUG STABILITY; DRUG STRUCTURE; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NORMAL HUMAN; PH MEASUREMENT; PRIORITY JOURNAL; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY;

ADMINISTRATION, ORAL; ANTIHYPERTENSIVE AGENTS; BENZOPYRANS; CHROMATOGRAPHY, LIQUID; DRUG COMBINATIONS; ETHANOLAMINES; HUMANS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY; TETRAZOLES; VALINE;

EID: 34848835442     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.08.016     Document Type: Article

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