Epidemiology of and risk factors for acinetobacter species bloodstream infection in children

Pediatric Infectious Disease Journal

Volumn 26, Issue 10, 2007, Pages 920-926

  Segal, Shana C ^a   Zaoutis, Theoklis E ^a,b   Kagen, Jessica ^a   Shah, Samir S ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Acinetobacter; Bloodstream infection; Children

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; AZATHIOPRINE; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE INHIBITOR; CARBAPENEM; CEFOTAXIME; CIPROFLOXACIN; CLINDAMYCIN; COTRIMOXAZOLE; CYCLOSPORIN; DEXAMETHASONE; IMIPENEM; METRONIDAZOLE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TACROLIMUS;

ACINETOBACTER; ADOLESCENT; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL INFECTION; BACTERIUM ISOLATE; BACTERIUM ISOLATION; BLOOD CULTURE; BLOOD DISEASE; BLOODSTREAM INFECTION; CASE CONTROL STUDY; CHILD; CONFIDENCE INTERVAL; CONTROLLED STUDY; FEMALE; GRAM NEGATIVE BACTERIUM; HOME CARE; HUMAN; INFANT; INFECTION; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PEDIATRIC HOSPITAL; PRIORITY JOURNAL; RANDOM SAMPLE; RETROSPECTIVE STUDY; RISK FACTOR; SOLID TUMOR; TERTIARY HEALTH CARE;

ACINETOBACTER; ACINETOBACTER INFECTIONS; ADOLESCENT; AGE FACTORS; ANTI-BACTERIAL AGENTS; BACTEREMIA; BLOOD; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CROSS INFECTION; DRUG RESISTANCE, BACTERIAL; FEMALE; HUMANS; INFANT; KIDNEY FAILURE; MALE; MICROBIAL SENSITIVITY TESTS; NEOPLASMS; RETROSPECTIVE STUDIES; RISK FACTORS; UNITED STATES;

EID: 34848828884     PISSN: 08913668     EISSN: None     Source Type: Journal    
DOI: 10.1097/INF.0b013e3180684310     Document Type: Article

References (54)

1. Cisneros JM, Rodriguez-Bano J. Nosocomial bacteremia due to Acinetobacter baumannii: epidemiology, clinical features and treatment. Clin Microbiol Infect. 2002;8:687-693.
2. Arora U, Jaitwani J. Acinetobacter spp. - an emerging pathogen in neonatal septicemia in Amritsar. Indian J Med Microbiol. 2006;24:81.
3. Beck-Sague CM, Jarvis WR, Brook JH, et al. Epidemic bacteremia due to Acinetobacter baumannii in five intensive care units. Am J Epidemiol. 1990;132:723-733.
4. Wisplinghoff H, Edmond MB, Pfaller MA, Jones RN, Wenzel RP, Seifert H. Nosocomial bloodstream infections caused by Acinetobacter species in United States hospitals: clinical features, molecular epidemiology, and antimicrobial susceptibility. Clin Infect Dis. 2000;31:690-697.
5. Jerassy Z, Yinnon AM, Mazouz-Cohen S, et al. Prospective hospitalwide studies of 505 patients with nosocomial bacteraemia in 1997 and 2002. J Hosp Infect. 2006;62:230-236.
6. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from October 1986-April 1998, issued June 1998. Am J Infect Control. 1998;26:522-533.
7. Fournier PE, Richet H. The epidemiology and control of Acinetobacter baumannii in health care facilities. Clin Infect Dis. 2006;42:692-699.
8. Jeena P, Thompson E, Nchabeleng M, Sturm A. Emergence of multidrug-resistant Acinetobacter anitratus species in neonatal and paediatric intensive care units in a developing country: concern about antimicrobial policies. Ann Trop Paediatr. 2001;21:245-251.
9. Gales AC, Jones RN, Forward KR, Linares J, Sader HS, Verhoef J. Emerging importance of multidrug-resistant Acinetobacter species and Stenotrophomonas maltophilia as pathogens in seriously ill patients: geographic patterns, epidemiological features, and trends in the SENTRY Antimicrobial Surveillance Program (1997-1999). Clin Infect Dis. 2001;32(suppl 2):S104-S113.
10. Acinetobacter baumannii infections among patients at military medical facilities treating injured U.S. service members, 2002-2004. MMWR Morb Mortal Wkly Rep. 2004;53:1063-1066.
11. Katragkou A, Kotsiou M, Antachopoulos C, et al. Acquisition of imipenem-resistant Acinetobacter baumannii in a pediatric intensive care unit: a case-control study. Intensive Care Med. 2006;32:1384-1391.
12. Anyebuno M, Newman M. Common causes of neonatal bacteraemia in Accra, Ghana. East Afr Med J. 1995;72:805-808.
13. Mishra A, Mishra S, Jaganath G, Mittal RK, Gupta PK, Patra DP. Acinetobacter sepsis in newborns. Indian Pediatr. 1998;35:27-32.
14. de Beaufort AJ, Bernards AT, Dijkshoorn L, van Boven CP. Acinetobacter junii causes life-threatening sepsis in preterm infants. Acta Paediatr. 1999;88:772-775.
15. Stone JW, Das BC. Investigation of an outbreak of infection with Acinetobacter calcoaceticus in a special care baby unit. J Hosp Infect. 1986;7:42-48.
16. Sakata H, Fujita K, Maruyama S, Kakehashi H, Mori Y, Yoshioka H. Acinetobacter calcoaceticus biovar anitratus septicaemia in a neonatal intensive care unit: epidemiology and control. J Hosp Infect. 1989;14:15-22.
17. Horrevorts A, Bergman K, Kollee L, Breuker I, Tjernberg I, Dijkshoorn L. Clinical and epidemiological investigations of Acinetobacter genomospecies 3 in a neonatal intensive care unit. J Clin Microbiol. 1995;33:1567-1572.
18. Ng PC, Herrington RA, Beane CA, Ghoneim AT, Dear PR. An outbreak of Acinetobacter septicaemia in a neonatal intensive care unit. J Hosp Infect. 1989;14:363-368.
19. Schloesser RL, Laufkoetter EA, Lehners T, Mietens C. An outbreak of Acinetobacter calcoaceticus infection in a neonatal care unit. Infection. 1990;18:230-233.
20. Regev R, Dolfin T, Zelig I, Givoni S, Wolach B. Acinetobacter septicemia: a threat to neonates? Special aspects in a neonatal intensive care unit. Infection. 1993;21:394-396.
21. Pillay T, Pillay DG, Adhikari M, Pillay A, Sturm AW. An outbreak of neonatal infection with Acinetobacter linked to contaminated suction catheters. J Hosp Infect. 1999;43:299-304.
22. Mittal N, Nair D, Gupta N, et al. Outbreak of Acinetobacter spp septicemia in a neonatal ICU. Southeast Asian J Trop Med Public Health. 2003;34:365-366.
23. Melamed R, Greenberg D, Porat N, et al. Successful control of an Acinetobacter baumannii outbreak in a neonatal intensive care unit. J Hosp Infect. 2003;53:31-38.
24. McDonald LC, Walker M, Carson L, et al. Outbreak of Acinetobacter spp. bloodstream infections in a nursery associated with contaminated aerosols and air conditioners. Pediatr Infect Dis J. 1998;17:716-722.
25. von Dolinger de Brito D, Oliveira EJ, Abdallah VO, da Costa Darini AL, Filho PP. An outbreak of Acinetobacter baumannii septicemia in a neonatal intensive care unit of a university hospital in Brazil. Braz J Infect Dis. 2005;9:301-309.
26. Huang YC, Su LH, Wu TL, et al. Outbreak of Acinetobacter baumannii bacteremia in a neonatal intensive care unit: clinical implications and genotyping analysis. Pediatr Infect Dis J. 2002;21:1105-1109.
27. Nagels B, Ritter E, Thomas P, Schulte-Wissermann H, Wirsing von Konig CH. Acinetobacter baumannii colonization in ventilated preterm infants. Eur J Clin Microbiol Infect Dis. 1998;17:37-40.
28. Larson EL, Cimiotti JP, Haas J, et al. Gram-negative bacilli associated with catheter-associated and non-catheter-associated bloodstream infections and hand carriage by healthcare workers in neonatal intensive care units. Pediatr Crit Care Med. 2005;6:457-461.
29. El-Mahallawy H, Sidhom I, El-Din NH, Zamzam M, El-Lamie MM. Clinical and microbiologic determinants of serious bloodstream infections in Egyptian pediatric cancer patients: a one-year study. Int J Infect Dis. 2005;9:43-51.
30. Kappstein I, Grundmann H, Hauer T, Niemeyer C. Aerators as a reservoir of Acinetobacter junii: an outbreak of bacteraemia in paediatric oncology patients. J Hosp Infect. 2000;44:27-30.
31. Fuchs GJ III, Jaffe N, Pickering LK. Acinetobacter calcoaceticus sepsis in children with malignancies. Pediatr Infect Dis. 1986;5:545-549.
32. Simon A, Bode U, Beutel K. Diagnosis and treatment of catheter-related infections in paediatric oncology: an update. Clin Microbiol Infect. 2006;12:606-620.
33. Koprnova J, Svetlansky I, Bilikova E, Babela R, Krcmery V. Acinetobacter baumanii bacteremia in children. Pediatr Infect Dis J. 2001;20:1183.
34. Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MB. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis. 2004;39:309-317.
35. Gaynes R, Edwards JR. Overview of nosocomial infections caused by gram-negative bacilli. Clin Infect Dis. 2005;41:848-854.
36. Levy I, Leibovici L, Drucker M, Samra Z, Konisberger H, Ashkenazi S. A prospective study of Gram-negative bacteremia in children. Pediatr Infect Dis J. 1996;15:117-122.
37. Richards MJ, Edwards JR, Culver DH, Gaynes RP. Nosocomial infections in pediatric intensive care units in the United States. National Nosocomial Infections Surveillance System. Pediatrics. 1999;103:e39.
38. Getchell-White SI, Donowitz LG, Groschel DH. The inanimate environment of an intensive care unit as a potential source of nosocomial bacteria: evidence for long survival of Acinetobacter calcoaceticus. Infect Control Hosp Epidemiol. 1989;10:402-407.
39. Rusin PA, Rose JB, Haas CN, Gerba CP. Risk assessment of opportunistic bacterial pathogens in drinking water. Rev Environ Contam Toxicol. 1997;152:57-83.
40. Ecker JA, Massire C, Hall TA, et al. Identification of Acinetobacter species and genotyping of Acinetobacter baumannii by multilocus PCR and mass spectrometry. J Clin Microbiol. 2006;44:2921-2932.
41. Richet H, Fournier PE. Nosocomial infections caused by Acinetobacter baumannii: a major threat worldwide. Infect Control Hosp Epidemiol. 2006;27:645-646.
42. McDonald LC, Banerjee SN, Jarvis WR. Seasonal variation of Acinetobacter infections: 1987-1996. Nosocomial Infections Surveillance System. Clin Infect Dis. 1999;29:1133-1137.
43. Retailliau HF, Hightower AW, Dixon RE, Allen JR. Acinetobacter calcoaceticus: a nosocomial pathogen with an unusual seasonal pattern. J Infect Dis. 1979;139:371-375.
44. Mulin B, Talon D, Viel JF, et al. Risk factors for nosocomial colonization with multiresistant Acinetobacter baumannii. Eur J Clin Microbiol Infect Dis. 1995;14:569-576.
45. Vahter M, Gochfeld M, Casati B, et al. Implications of gender differences for human health risk assessment and toxicology. Environ Res. 2007;104:70-84.
46. Tran D, Phongsavan P, Bauman AE, Havea D, Galea G. Hygiene behaviour of adolescents in the Pacific: associations with socio-demographic, health behaviour and school environment. Asia Pac J Public Health. 2006;18:3-11.
47. Kaciuba-Uscilko H, Grucza R. Gender differences in thermoregulation. Curr Opin Clin Nutr Metab Care. 2001;4:533-536.
48. Abrutyn E, Goodhart GL, Roos K, Anderson R, Buxton A. Acinetobacter calcoaceticus outbreak associated with peritoneal dialysis. Am J Epidemiol. 1978;107:328-335.
49. Kantor RJ, Carson LA, Graham DR, Petersen NJ, Favero MS. Outbreak of pyrogenic reactions at a dialysis center. Association with infusion of heparinized saline solution. Am J Med. 1983;74:449-456.
50. Valdez JM, Asperilla MO, Smego RA Jr. Acinetobacter peritonitis in patients receiving continuous ambulatory peritoneal dialysis. South Med J. 1991;84:607-610.
51. Flaherty JP, Garcia-Houchins S, Chudy R, Arnow PM. An outbreak of gram-negative bacteremia traced to contaminated O-rings in reprocessed dialyzers. Ann Intern Med. 1993;119:1072-1078.
52. Taylor G, Gravel D, Johnston L, Embil J, Holton D, Paton S. Incidence of bloodstream infection in multicenter inception cohorts of hemodialysis patients. Am J Infect Control. 2004;32:155-160.
53. Taylor GD, McKenzie M, Buchanan-Chell M, Caballo L, Chui L, Kowalewska-Grochowska K. Central venous catheters as a source of hemodialysis-related bacteremia. Infect Control Hosp Epidemiol. 1998;19:643-646.
54. Ladhani S, Gransden W. Septicaemia due to glucose non-fermenting, gram-negative bacilli other than Pseudomonas aeruginosa in children. Acta Paediatr. 2002;91:303-306.