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Volumn 9, Issue 5, 2007, Pages 317-322

Biweekly docetaxel and gemcitabine as neoadjuvant chemotherapy followed by adjuvant doxorubicin and cyclophosphamide therapy in stage II and III breast cancer patients: Results of a phase II study

Author keywords

Breast cancer; Docetaxel; Gemcitabine; Preoperative treatment

Indexed keywords

CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN; GEMCITABINE; ANTINEOPLASTIC AGENT; DEOXYCYTIDINE; DRUG DERIVATIVE; TAXOID;

EID: 34848826289     PISSN: 1699048X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12094-007-0059-7     Document Type: Article
Times cited : (4)

References (39)
  • 1
    • 0018180337 scopus 로고
    • Combined chemotherapy-radiotherapy approach in locally advanced (T3b-T4) breast cancer
    • De Lena M, Zucali R, Viganotti G et al (1978) Combined chemotherapy-radiotherapy approach in locally advanced (T3b-T4) breast cancer. Cancer Chemother Pharmacol 1:53-59
    • (1978) Cancer Chemother Pharmacol , vol.1 , pp. 53-59
    • De Lena, M.1    Zucali, R.2    Viganotti, G.3
  • 2
    • 13744257860 scopus 로고    scopus 로고
    • Neoadjuvant versus adjuvant systemic treatment in breast cancer: A meta-analysis
    • Mauri D, Pavlidis N, Ioannidis JP (2005) Neoadjuvant versus adjuvant systemic treatment in breast cancer: A meta-analysis. J Natl Cancer Inst 97:188-194
    • (2005) J Natl Cancer Inst , vol.97 , pp. 188-194
    • Mauri, D.1    Pavlidis, N.2    Ioannidis, J.P.3
  • 3
    • 0037137519 scopus 로고    scopus 로고
    • A gene-expression signature as a predictor of survival in breast cancer
    • Van de Vijver MJ, He YD, van't Verr LJ et al (2002) A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 347:1999-2009
    • (2002) N Engl J Med , vol.347 , pp. 1999-2009
    • Van de Vijver, M.J.1    He, Y.D.2    van't Verr, L.J.3
  • 4
    • 0031926839 scopus 로고    scopus 로고
    • Effect of preoperative chemotherapy on the outcome of women with operable breast cancer
    • Fisher B, Bryant J, Wolmark N et al (1998) Effect of preoperative chemotherapy on the outcome of women with operable breast cancer. J Clin Oncol 16:2672-2685
    • (1998) J Clin Oncol , vol.16 , pp. 2672-2685
    • Fisher, B.1    Bryant, J.2    Wolmark, N.3
  • 5
    • 0035751675 scopus 로고    scopus 로고
    • Preoperative chemotherapy in patients with operable breast cancer: Nine-year results from National Surgical Adjuvant Breast and Bowel Project B-18
    • Wolmark N, Wang J, Mamounas E et al (2001) Preoperative chemotherapy in patients with operable breast cancer: Nine-year results from National Surgical Adjuvant Breast and Bowel Project B-18. J Natl Cancer Inst Monogr (30): 96-102
    • (2001) J Natl Cancer Inst Monogr , vol.30 , pp. 96-102
    • Wolmark, N.1    Wang, J.2    Mamounas, E.3
  • 6
    • 0037041610 scopus 로고    scopus 로고
    • Prognostic significance of a complete pathological response after induction chemotherapy in operable breast cancer
    • Chollet P, Amat S, Cure H et al (2002) Prognostic significance of a complete pathological response after induction chemotherapy in operable breast cancer. Br J Cancer 86:1041-1046
    • (2002) Br J Cancer , vol.86 , pp. 1041-1046
    • Chollet, P.1    Amat, S.2    Cure, H.3
  • 7
    • 0031972858 scopus 로고    scopus 로고
    • Primary chemotherapy in operable breast cancer: Eight-year experience at the Milan Cancer Institute
    • Bonadonna G, Valagussa P, Brambilla C et al (1998) Primary chemotherapy in operable breast cancer: Eight-year experience at the Milan Cancer Institute. J Clin Oncol 16:93-100
    • (1998) J Clin Oncol , vol.16 , pp. 93-100
    • Bonadonna, G.1    Valagussa, P.2    Brambilla, C.3
  • 8
    • 0032787785 scopus 로고    scopus 로고
    • Prospective randomized trial of docetaxel versus doxorubicin in patients with metastatic breast cancer
    • Chan S, Friedrichs K, Noel D et al (1999) Prospective randomized trial of docetaxel versus doxorubicin in patients with metastatic breast cancer. J Clin Oncol 17:2341-2354
    • (1999) J Clin Oncol , vol.17 , pp. 2341-2354
    • Chan, S.1    Friedrichs, K.2    Noel, D.3
  • 9
    • 0037445247 scopus 로고    scopus 로고
    • Docetaxel and doxorubicin compared with doxorubicin and cyclophosphamide as first-line chemotherapy for metastatic breast cancer: Results of a randomized, multicenter, phase III trial
    • Nabholtz JM, Falkson C, Campos D et al (2003) Docetaxel and doxorubicin compared with doxorubicin and cyclophosphamide as first-line chemotherapy for metastatic breast cancer: Results of a randomized, multicenter, phase III trial. J Clin Oncol 21:968-975
    • (2003) J Clin Oncol , vol.21 , pp. 968-975
    • Nabholtz, J.M.1    Falkson, C.2    Campos, D.3
  • 10
    • 21144435932 scopus 로고    scopus 로고
    • Adjuvant docetaxel for node-positive breast cancer
    • Martin M, Pienkowski T, Mackey J et al (2005) Adjuvant docetaxel for node-positive breast cancer. N Engl J Med 352:2302-2313
    • (2005) N Engl J Med , vol.352 , pp. 2302-2313
    • Martin, M.1    Pienkowski, T.2    Mackey, J.3
  • 11
    • 0037314676 scopus 로고    scopus 로고
    • Weekly docetaxel as neoadjuvant chemotherapy for stage II and III breast cancer: Efficacy and correlation with biological markers in a phase II, multicenter study
    • Estevez LG, Cuevas JM, Antón A et al (2003) Weekly docetaxel as neoadjuvant chemotherapy for stage II and III breast cancer: Efficacy and correlation with biological markers in a phase II, multicenter study. Clin Cancer Res 9:686-692
    • (2003) Clin Cancer Res , vol.9 , pp. 686-692
    • Estevez, L.G.1    Cuevas, J.M.2    Antón, A.3
  • 12
    • 0030794314 scopus 로고    scopus 로고
    • Docetaxel as neoadjuvant chemotherapy in patients with stage III breast cancer
    • Gradishar WJ (1997) Docetaxel as neoadjuvant chemotherapy in patients with stage III breast cancer. Oncology (Huntingt) 11[8 Suppl 8]: 15-18
    • (1997) Oncology (Huntingt) , vol.11 , Issue.8 SUPPL. 8 , pp. 15-18
    • Gradishar, W.J.1
  • 13
    • 0037087562 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy in breast cancer: Significantly enhanced response with docetaxel
    • Smith IC, Heys SD, Hutcheon AW et al (2002) Neoadjuvant chemotherapy in breast cancer: Significantly enhanced response with docetaxel. J Clin Oncol 20:1456-1466
    • (2002) J Clin Oncol , vol.20 , pp. 1456-1466
    • Smith, I.C.1    Heys, S.D.2    Hutcheon, A.W.3
  • 14
    • 0642347622 scopus 로고    scopus 로고
    • The effect on tumor response of adding sequential preoperative docetaxel to preoperative doxorubicin and cyclophosphamide: Preliminary results from National Surgical Adjuvant Breast and Bowel Project Protocol B-27
    • Bear HD, Anderson S, Brown A et al (2003) The effect on tumor response of adding sequential preoperative docetaxel to preoperative doxorubicin and cyclophosphamide: Preliminary results from National Surgical Adjuvant Breast and Bowel Project Protocol B-27. J Clin Oncol 21:4165-4174
    • (2003) J Clin Oncol , vol.21 , pp. 4165-4174
    • Bear, H.D.1    Anderson, S.2    Brown, A.3
  • 15
    • 33646445341 scopus 로고    scopus 로고
    • Sequential preoperative or postoperative docetaxel added to preoperative doxorubicin plus cyclophosphamide for operable breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-27
    • Bear HD, Anderson S, Smith RE et al (2006) Sequential preoperative or postoperative docetaxel added to preoperative doxorubicin plus cyclophosphamide for operable breast cancer: National Surgical Adjuvant Breast and Bowel Project Protocol B-27. J Clin Oncol 24:2019-2027
    • (2006) J Clin Oncol , vol.24 , pp. 2019-2027
    • Bear, H.D.1    Anderson, S.2    Smith, R.E.3
  • 16
    • 0028799915 scopus 로고
    • Advanced breast cancer: A phase II trial with gemcitabine
    • Carmichael J, Possinger K, Phillip P et al (1995) Advanced breast cancer: A phase II trial with gemcitabine. J Clin Oncol 13:2731-2736
    • (1995) J Clin Oncol , vol.13 , pp. 2731-2736
    • Carmichael, J.1    Possinger, K.2    Phillip, P.3
  • 17
    • 0342647532 scopus 로고    scopus 로고
    • Gemcitabine in combination with doxorubicin in advanced breast cancer: Final results of a phase II pharmacokinetic trial
    • Perez-Manga G, Lluch A, Alba E et al (2000) Gemcitabine in combination with doxorubicin in advanced breast cancer: Final results of a phase II pharmacokinetic trial. J Clin Oncol 18:2545-2552
    • (2000) J Clin Oncol , vol.18 , pp. 2545-2552
    • Perez-Manga, G.1    Lluch, A.2    Alba, E.3
  • 18
    • 0033956168 scopus 로고    scopus 로고
    • Paclitaxel/gemcitabine administered every two weeks in advanced breast cancer: Preliminary results of a phase II trial
    • Colomer R, Llombart A, Lluch A et al (2000) Paclitaxel/gemcitabine administered every two weeks in advanced breast cancer: Preliminary results of a phase II trial. Semin Oncol 27[1 Suppl 2]:20-24
    • (2000) Semin Oncol , vol.27 , Issue.1 SUPPL. 2 , pp. 20-24
    • Colomer, R.1    Llombart, A.2    Lluch, A.3
  • 19
    • 0034885618 scopus 로고    scopus 로고
    • A phase II study of neoadjuvant gemcitabine plus doxorubicin in stage IIIB breast cancer: A preliminary report
    • Gomez H, Kahatt C, Falcon S et al (2001) A phase II study of neoadjuvant gemcitabine plus doxorubicin in stage IIIB breast cancer: A preliminary report. Semin Oncol 28[3 Suppl 10]:57-61
    • (2001) Semin Oncol , vol.28 , Issue.3 SUPPL. 10 , pp. 57-61
    • Gomez, H.1    Kahatt, C.2    Falcon, S.3
  • 20
    • 0036074995 scopus 로고    scopus 로고
    • Neoadjuvant gemcitabine therapy for breast cancer
    • [review]
    • Sanchez-Rovira P, Jaen A, Dueñas R et al (2002) Neoadjuvant gemcitabine therapy for breast cancer [review]. Clin Breast Cancer 3[Suppl 1]:39-44
    • (2002) Clin Breast Cancer , vol.3 , Issue.SUPPL. 1 , pp. 39-44
    • Sanchez-Rovira, P.1    Jaen, A.2    Dueñas, R.3
  • 21
    • 9144256622 scopus 로고    scopus 로고
    • Evidence for in vivo synergism between docetaxel and gemcitabine in patients with metastatic breast cancer
    • Alexopoulos A, Tryfonopoulos D, Karamouzis MV et al (2004) Evidence for in vivo synergism between docetaxel and gemcitabine in patients with metastatic breast cancer. Ann Oncol 15: 95-99
    • (2004) Ann Oncol , vol.15 , pp. 95-99
    • Alexopoulos, A.1    Tryfonopoulos, D.2    Karamouzis, M.V.3
  • 22
    • 0032996301 scopus 로고    scopus 로고
    • Salvage chemotherapy in anthracycline-pretreated metastatic breast cancer patients with docetaxel and gemcitabine: A multicenter phase II trial. Greek Breast Cancer Cooperative Group
    • Mavroudis D, Malamos N, Alexopoulos A et al (1999) Salvage chemotherapy in anthracycline-pretreated metastatic breast cancer patients with docetaxel and gemcitabine: A multicenter phase II trial. Greek Breast Cancer Cooperative Group. Ann Oncol 10:211-215
    • (1999) Ann Oncol , vol.10 , pp. 211-215
    • Mavroudis, D.1    Malamos, N.2    Alexopoulos, A.3
  • 23
    • 0033931583 scopus 로고    scopus 로고
    • Docetaxel and gemcitabine in anthracycline-resistant advanced breast cancer: A Hellenic Cooperative Oncology Group phase II study
    • Fountzilas G, Nicolaides C, Bafaloukos D et al (2000) Docetaxel and gemcitabine in anthracycline-resistant advanced breast cancer: A Hellenic Cooperative Oncology Group phase II study. Cancer Invest 18:503-509
    • (2000) Cancer Invest , vol.18 , pp. 503-509
    • Fountzilas, G.1    Nicolaides, C.2    Bafaloukos, D.3
  • 24
    • 0034772092 scopus 로고    scopus 로고
    • Monthly docetaxel and weekly gemcitabine in metastatic breast cancer: A phase II trial
    • Laufman LR, Spiridonidis CH, Pritchard J et al (2001) Monthly docetaxel and weekly gemcitabine in metastatic breast cancer: A phase II trial. Ann Oncol 12:1259-1264
    • (2001) Ann Oncol , vol.12 , pp. 1259-1264
    • Laufman, L.R.1    Spiridonidis, C.H.2    Pritchard, J.3
  • 25
    • 30544441289 scopus 로고    scopus 로고
    • A phase II study of first-line combination chemotherapy with docetaxel and gemcitabine in anthracycline-pretreated, Her2-negative metastatic breast cancer (MBC)
    • [abstract]. (abstr 455)
    • Lenz F, Beldermann F, Geberth M et al (2003) A phase II study of first-line combination chemotherapy with docetaxel and gemcitabine in anthracycline-pretreated, Her2-negative metastatic breast cancer (MBC) [abstract]. Eur J Cancer 1: S139 (abstr 455)
    • (2003) Eur J Cancer , vol.1
    • Lenz, F.1    Beldermann, F.2    Geberth, M.3
  • 26
    • 0036091283 scopus 로고    scopus 로고
    • Treatment of advanced breast cancer with docetaxel and gemcitabine with and without human granulocyte colony-stimulating factor
    • Kornek GV, Haider K, Kwasny W et al (2002) Treatment of advanced breast cancer with docetaxel and gemcitabine with and without human granulocyte colony-stimulating factor. Clin Cancer Res 8:1051-1056
    • (2002) Clin Cancer Res , vol.8 , pp. 1051-1056
    • Kornek, G.V.1    Haider, K.2    Kwasny, W.3
  • 27
    • 2442643900 scopus 로고    scopus 로고
    • Novel association with gemcitabine and docetaxel as salvage chemotherapy in metastatic breast cancer previously treated with anthracyclines: Results of a multicenter phase II study
    • and the Grupo Oncologico Italia Meridionale
    • Brandi M, Vici P, Lopez M et al and the Grupo Oncologico Italia Meridionale (2004) Novel association with gemcitabine and docetaxel as salvage chemotherapy in metastatic breast cancer previously treated with anthracyclines: Results of a multicenter phase II study. Semin Oncol 31[2 Suppl 5]:13-19
    • (2004) Semin Oncol , vol.31 , Issue.2 SUPPL. 5 , pp. 13-19
    • Brandi, M.1    Vici, P.2    Lopez, M.3
  • 28
    • 49849094667 scopus 로고    scopus 로고
    • Combination chemotherapy with docetaxel and gemcitabine in anthracycline pretreated patients with metastatic breast cancer (MBC)
    • [abstract]. (abstr 728)
    • Slee PH, Jong PC, Jong RS et al (2005) Combination chemotherapy with docetaxel and gemcitabine in anthracycline pretreated patients with metastatic breast cancer (MBC) [abstract]. J Clin Oncol 23[16S, Part I]: 60s (abstr 728)
    • (2005) J Clin Oncol , vol.23 , Issue.16 S
    • Slee, P.H.1    Jong, P.C.2    Jong, R.S.3
  • 29
    • 30544455528 scopus 로고    scopus 로고
    • Docetaxel/gemcitabine administered every other week as first-line treatment for metastatic breast cancer: Final results of a phase II trial
    • and the Spanish Group for Breast Cancer Research GEICAM)
    • Pelegri A, Calvo L, Anton A et al and the Spanish Group for Breast Cancer Research GEICAM) (2005) Docetaxel/gemcitabine administered every other week as first-line treatment for metastatic breast cancer: Final results of a phase II trial. Clin Breast Cancer 6:433-438 433-438
    • (2005) Clin Breast Cancer , vol.6 , pp. 433-438
    • Pelegri, A.1    Calvo, L.2    Anton, A.3
  • 30
    • 23844469121 scopus 로고    scopus 로고
    • Weekly docetaxel and gemcitabine as first-line treatment for metastatic breast cancer: Results of a multicenter phase II study
    • [review]
    • Palmeri S, Vaglica M, Spada S et al (2005) Weekly docetaxel and gemcitabine as first-line treatment for metastatic breast cancer: results of a multicenter phase II study [review]. Oncology 68:438-445
    • (2005) Oncology , vol.68 , pp. 438-445
    • Palmeri, S.1    Vaglica, M.2    Spada, S.3
  • 31
    • 9244254315 scopus 로고    scopus 로고
    • Front-line chemotherapy with docetaxel and gemcitabine administered every two weeks in patients with metastatic breast cancer: A multicenter phase II study
    • and the Breast Cancer Study Group of the Hellenic Oncology Research Group (HORG)
    • Mavroudis D, Malamos N, Polyzos A et al and the Breast Cancer Study Group of the Hellenic Oncology Research Group (HORG) (2004) Front-line chemotherapy with docetaxel and gemcitabine administered every two weeks in patients with metastatic breast cancer: A multicenter phase II study. Oncology 67:250-256
    • (2004) Oncology , vol.67 , pp. 250-256
    • Mavroudis, D.1    Malamos, N.2    Polyzos, A.3
  • 32
    • 0032998048 scopus 로고    scopus 로고
    • Adjuvant breast cancer therapy: Current status and future strategies - Growth kinetics and the improved drug therapy of breast cancer
    • [review]
    • Norton L (1999) Adjuvant breast cancer therapy: Current status and future strategies - growth kinetics and the improved drug therapy of breast cancer [review]. Semin Oncol 26[1 Suppl 3]:1-4
    • (1999) Semin Oncol , vol.26 , Issue.1 SUPPL. 3 , pp. 1-4
    • Norton, L.1
  • 34
    • 49849096050 scopus 로고    scopus 로고
    • National Cancer Institute, Cancer Therapy Evaluation Program(CTEP) [database on the internet]. Common Toxicity Criteria, Version 2.0 [published 1999 April 30; cited Nov 15]. Available from:
    • National Cancer Institute, Cancer Therapy Evaluation Program(CTEP) Reporting Guidelines [database on the internet]. Common Toxicity Criteria, Version 2.0 [published 1999 April 30; cited 2005 Nov 15]. Available from: http://ctep.cancer.gov/reporting/CTC-3test.html
    • (2005) Reporting Guidelines
  • 35
    • 29244467646 scopus 로고    scopus 로고
    • European Cooperative Trial in Operable Breast Cancer (ECTO): Improved freedom from progression (FFP) from adding paclitaxel (T) to doxorubicin (A) followed by cyclophosphamide methotrexate and fluorouracil (CMF)
    • [abstract] (abstr 513)
    • Gianni L, Baselga L, Eiermann W et al (2005) European Cooperative Trial in Operable Breast Cancer (ECTO): Improved freedom from progression (FFP) from adding paclitaxel (T) to doxorubicin (A) followed by cyclophosphamide methotrexate and fluorouracil (CMF) [abstract]. J Clin Oncol 23[16S, Part I]: 7s (abstr 513)
    • (2005) J Clin Oncol , vol.23 , Issue.16 S
    • Gianni, L.1    Baselga, L.2    Eiermann, W.3
  • 36
    • 0033050164 scopus 로고    scopus 로고
    • Clinical course of breast cancer patients with complete pathologic primary tumor and axillary lymph node response to doxorubicin-based neoadjuvant chemotherapy. J
    • Kuerer HM, Newman LA, Smith TL et al (1999) Clinical course of breast cancer patients with complete pathologic primary tumor and axillary lymph node response to doxorubicin-based neoadjuvant chemotherapy. J Clin Oncol 17:460-469
    • (1999) Clin Oncol , vol.17 , pp. 460-469
    • Kuerer, H.M.1    Newman, L.A.2    Smith, T.L.3
  • 37
    • 0012812281 scopus 로고    scopus 로고
    • Pathologically involved axillary nodes following primary chemotherapy (PCT) in locally advanced breast cancer (LABC) is an early biological prognostic factor of long-term outcome in patients with LABC: The University of Texas MD Anderson Cancer Center experience
    • (abstr 132P) [abstract]
    • Valero V, Buzdar AU, Kau S-W et al (2002) Pathologically involved axillary nodes following primary chemotherapy (PCT) in locally advanced breast cancer (LABC) is an early biological prognostic factor of long-term outcome in patients with LABC: The University of Texas MD Anderson Cancer Center experience [abstract]. Ann Oncol 13[Suppl 5]: 37 (abstr 132P)
    • (2002) Ann Oncol , vol.13 , Issue.SUPPL. 5 , pp. 37
    • Valero, V.1    Buzdar, A.U.2    Kau, S.-W.3
  • 38
    • 2942702177 scopus 로고    scopus 로고
    • The use of alternate, non-cross-resistant adjuvant chemotherapy on the basis of pathologic response to a neoadjuvant doxorubicin-based regimen in women with operable breast cancer: Long-term results from a prospective randomized trial
    • Thomas E, Holmes FA, Smith TL et al (2004) The use of alternate, non-cross-resistant adjuvant chemotherapy on the basis of pathologic response to a neoadjuvant doxorubicin-based regimen in women with operable breast cancer: Long-term results from a prospective randomized trial. J Clin Oncol 22:2294-2302
    • (2004) J Clin Oncol , vol.22 , pp. 2294-2302
    • Thomas, E.1    Holmes, F.A.2    Smith, T.L.3
  • 39
    • 0036098442 scopus 로고    scopus 로고
    • Evaluation of paclitaxel in adjuvant chemotherapy for patients with operable breast cancer: Preliminary data of a prospective randomized trial
    • Buzdar AU, Singletary SE, Valero V et al (2002) Evaluation of paclitaxel in adjuvant chemotherapy for patients with operable breast cancer: preliminary data of a prospective randomized trial. Clin Cancer Res 8:1073-1079
    • (2002) Clin Cancer Res , vol.8 , pp. 1073-1079
    • Buzdar, A.U.1    Singletary, S.E.2    Valero, V.3


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