Technetium-99m 2-methoxy-isobutyl-isonitrile uptake scintigraphy in detection of the bone marrow infiltration in multiple myeloma: Correlation with MRI and other prognostic factors

Annals of Hematology

Volumn 86, Issue 11, 2007, Pages 805-813

  Erten, N ^a   Saka, B ^a   Berberoglu, K ^a   Turkmen, C ^a   Unal, S ^a   Bakir, B ^a   Yekeler, E ^a   Besisik, S K ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Magnetic resonance imaging; Multiple myeloma; Tc 99m methoxy 2 isobutylisonitrile

Indexed keywords

ANTINEOPLASTIC AGENT; BETA 2 MICROGLOBULIN; BIOCHEMICAL MARKER; IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN G; IMMUNOGLOBULIN LIGHT CHAIN; LACTATE DEHYDROGENASE; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M; PARAPROTEIN;

ADULT; AGED; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; BONE MARROW METASTASIS; BONE RADIOGRAPHY; CANCER INFILTRATION; CANCER REGRESSION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC ACCURACY; DISEASE ACTIVITY; DRUG MEGADOSE; FEMALE; HUMAN; INTERMETHOD COMPARISON; LACTATE DEHYDROGENASE BLOOD LEVEL; MALE; MULTIPLE MYELOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; SENSITIVITY AND SPECIFICITY; WHOLE BODY SCINTISCANNING;

ADULT; AGED; BETA 2-MICROGLOBULIN; BIOLOGICAL MARKERS; BONE MARROW; FEMALE; HUMANS; IMMUNOGLOBULIN M; L-LACTATE DEHYDROGENASE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MULTIPLE MYELOMA; RADIOPHARMACEUTICALS; SENSITIVITY AND SPECIFICITY; TECHNETIUM TC 99M SESTAMIBI;

EID: 34848816607     PISSN: 09395555     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00277-007-0329-z     Document Type: Article

References (19)

1. Ak I, Aslan V, Vardareli E, Gulbas Z (2003) Tc-99m methoxy isobutylisonitrile bone marrow imaging for predicting the levels of myeloma cells in bone marrow in multiple myeloma: Correlation with CD38/ CD138 expressing myeloma cells. Ann Hematol 82:88-92
2. Alexandrakis MG, Kyriakou DS, Passam FH, Malliaraki N, Christophoridou AV, Karkavitsas N (2002) Correlation between the uptake of Tc-99m-sestaMIBI and prognostic factors in patients with multiple myeloma. Clin Lab Haematol 24:155-159
3. Attal M, Harousseau JL, Stoppa AM, Sotta JJ, Fuzibet JG, Rossi JF, Cassassus P, Maissonneuve H, Facon T, Ifrah N, Payen C, Bataille R (1996) A prospective randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. N Engl J Med 335:91-97
4. Bacovsky J, Scudla V, Myslivecek M, Nekula J, Vytrasova M (2005) Scintigraphy using (99 m)Tc-MIBI (sestamibi), a sensitive parameter of activity of multiple myeloma. Neoplasma 52:302-306
5. Baur-Melnyk A, Buhmann S, Durr HR, Reiser M (2005) Role of MRI for the diagnosis and prognosis of multiple myeloma. Eur J Radiol 55:56-63
6. Catalano L, Pace L, Califano C, Pinto AM, De Renzo A, Di Gennaro F, Del Vecchio S, Fonti R, Salvatore M (1999) Detection of focal myeloma lesions by technetium-99 m-sestaMIBI scintigraphy. Haematologica 84:119-124
7. Del Vecchio S, Ciarmiello A, Pace L, Potena MI, Carriero MV, Mainolfi C, Thomas R, D'Aiuto G, Tsuruo T, Salvatore M (1997) Fractional retention of technetium-99 m-sestamibi as an index of P-glycoprotein expression in untreated breast cancer. J Nucl Med 38:1348-1351
8. Durie BGM, Salmon SE (1975) A clinical stating system for multiple myeloma. Cancer 36:842-854
9. Durie BGM, Waxman A, Jochelson M, Giles FJ, Hamburg S, Avedon M (1994) Technetium-99m-MIBI scanning in multiple myeloma. Proc Am Soc Clin Oncol 13:411a
10. Durie BGM (2006) The role of anatomic and functional staging in myeloma: description of Durie/Salmon plus staging system. Eur J Cancer 42:1539-1543
11. Fonti R, Del Vecchio S, Zannetti A, De Renzo A, Di Gennaro F, Catalano L, Califano C, Pace L, Rotoli B, Salvatore M (2001) Bone marrow uptake of 99mTc-MIBI in patients with multiple myeloma. Eur J Nucl Med 28:214-220
12. Lindstrom E, Lindstrom FD (1980) Skeletal scintigraphy with technetium diphosphonate in multiple myeloma - a comparison with skeletal X-ray. Acta Med Scand 208:289-291
13. Mirzaei S, Filipits M, Keck A, Bergmayer W, Knoll P, Koehn H, Ludwig H, Pecherstorfer M (2003) Comparison of Technetium-99m-MIBI imaging with MRI for detection of spine involvement in patients with multiple myeloma. BMC Nucl Med 3:2
14. Moulopoulos LA, Varma DG, Dimopoulos MA, Leeds NE, Kim EE, Johnston DA, Alexanian R, Libshitz HI (1992) Multiple myeloma: Spinal MR imaging in patients with untreated newly diagnosed disease. Radiology 185:833-840
15. Moulopoulos LA, Dimopoulos MA (2004) Radiologic features of multiple myeloma. In: Malpas JS, Bergsagel DE, Kyle RA, Anderson KC (eds) Myeloma biology and management, 3rd edn. Elsevier, USA, pp 175-185
16. Otsuka N, Fukunaga M, Morita K, Ono S, Nagai K, Yamada O, Yawata Y (1993) Bone and 67Ga scintigraphy in the evaluation of rib lesions in patients with multiple myeloma. Radiat Med 11:75-80
17. Pace L, Catalano L, Pinto AM, Renzo A, Di Gennaro F, Califano C, Del Vecchio S, Rotoli B, Salvatore M (1998) Different patterns of technetium-99 sestamibi uptake in multiple myeloma. Eur J Nucl Med 25:714-720
18. Tirovola EB, Biassoni L, Britton KE, Kaleva N, Kouykin V, Malpas JS (1996) The use of 99mTc-MIBI scanning in multiple myeloma. Br J Cancer 74:1815-1820
19. Vande Berg BC, Lecouvet FE, Michaux L, Ferrant A, Maldague B, Malghem J (1998) Magnetic resonance imaging of the bone marrow in hematological malignancies. Eur Radiol 8:1335-1344