Stereochemical identification of (R)- and (S)-ibuprofen using residual dipolar couplings, NMR, and modeling

Chirality

Volumn 19, Issue 9, 2007, Pages 741-750

  Marathias, Vasilios M ^a   Tawa, Gregory J ^a   Goljer, Igor ^a   Bach II, Alvin C ^a  

^a PFIZER INC   (United States)

Author keywords

Alignment media; Dipolar coupling; Enantiomer, chiral; PBLG; Small molecule

Indexed keywords

CADMIUM CHLORIDE; IBUPROFEN; POLY GAMMA BENZYL GLUTAMATE; POLYPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DRUG CONFORMATION; DRUG IDENTIFICATION; ENANTIOMER; LIQUID CRYSTAL; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; STEREOCHEMISTRY; VISCOSITY;

CHEMISTRY, ORGANIC; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; IBUPROFEN; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; MODELS, THEORETICAL; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; SOLVENTS; STEREOISOMERISM; TECHNOLOGY, PHARMACEUTICAL;

EID: 34748914846     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20338     Document Type: Article

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