Haemostatic changes and acquired activated protein C resistance in normal pregnancy

Blood Coagulation and Fibrinolysis

Volumn 18, Issue 7, 2007, Pages 685-688

  Mahieu, Boris ^a   Jacobs, Nadia ^a   Mahieu, Sarah ^a   Naelaerts, Kristine ^a   Vertessen, Francine ^a   Weyler, Joost ^b   Jacquemyn, Yves ^a   Van Der Planken, Marc ^a  

^a ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^b UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Activated partial thromboplastin time; Activated protein C resistance; Factor VIII; Pregnancy; Protein C; Protein S

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 8; PROTEIN C; PROTEIN S; VON WILLEBRAND FACTOR;

ADULT; ANTICOAGULATION; ARTICLE; FEMALE; GESTATIONAL AGE; HEMOSTASIS; HUMAN; NORMAL HUMAN; PARTIAL THROMBOPLASTIN TIME; PREGNANCY; PRIORITY JOURNAL; PUERPERIUM; SECOND TRIMESTER PREGNANCY; SENSITIVITY ANALYSIS; STEREOSPECIFICITY; THIRD TRIMESTER PREGNANCY;

ACTIVATED PROTEIN C RESISTANCE; ADULT; CROSS-SECTIONAL STUDIES; FACTOR V; FACTOR VIII; FEMALE; HUMANS; PARTIAL THROMBOPLASTIN TIME; PREGNANCY; PREGNANCY TRIMESTERS; PROTEIN C; PROTEIN C DEFICIENCY; PROTEIN S; PROTEIN S DEFICIENCY; RISK FACTORS; VON WILLEBRAND FACTOR;

EID: 34748909461     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/MBC.0b013e3282f09835     Document Type: Article

References (11)

1. Rai R, Shlebak A, Cohen H, Backos M, Holmes Z, Marriott K, et al. Factor V Leiden and acquired activated protein C resistance among 1000 women with recurrent miscarriage. Hum Reprod 2001; 16:961-965.
2. Brenner B. Haemostatic changes in pregnancy. Thromb Res 2004; 114(5-6):409-414.
3. Yale SA, De-Hui WK. Thrombophilia and pregnancy: review of the literature and some original data. Clin Appl Thromb Hemost 2001; 7:259-268.
4. Kutteh WH, Triplett DA. Thrombophilias and recurrent pregnancy loss. Semin Reprod Med 2006; 24:54-66.
5. Bertina RM, Koeleman BP, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, et al. Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 1994; 369:64-67.
6. Marcucci R, Abbate R, Fedi S, Gori AM, Brunelli T, Bruni V, et al. Acquired activated protein C resistance in postmenopausal women is dependant on factor VIII:c levels. Am J Clin Pathol 1999; 111:769-772.
7. Lindqvist PG, Svensson P, Dahlback B. Activated proteine C resistance - in the absence of factor V Leiden - and pregnancy. J Thromb Haemost 2006; 4:361-366.
8. Paternoster DM, Stella A, Simioni P, Girolami A, Snijders D. Activated protein C resistance in normal and preeclamptic pregnancies. Gynecol Obstet Invest 2002; 54:145-149.
9. Schneider DM, van Tempelhoff GF, Hoppenstaedt D, Fareed J, Heilmann L. Acquired resistance to activated protein C in pregnancy. Z Geburtshilfe Neonatol 1998; 202:107-110.
10. Walker MC, Garner PR, Keely EJ, Rock GA, Reis MD. Changes in activated protein C resistance during normal pregnancy. Am J Obstet Gynecol 1997; 177:162-169.
11. Cumming AM, Tait RC, Fildes S, Yoong A, Keeney S, Hay CRM. Development of resistance to activated protein C during pregnancy. Br J Haematol 1995; 90:725-727.