Evaluation of centrally acting cholinesterase inhibitor exposures in adults

Annals of Pharmacotherapy

Volumn 41, Issue 10, 2007, Pages 1632-1637

  McCain, Keith R ^a   Sawyer, Tama S ^b   Spiller, Henry A ^c  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b UNIVERSITY OF KANSAS HOSPITAL   (United States)

^c KENTUCKY REGIONAL POISON CENTER   (United States)

Author keywords

Cholinesterase inhibitor; Overdose; Poison

Indexed keywords

ACTIVATED CARBON; ANTIARRHYTHMIC AGENT; ANTICONVULSIVE AGENT; ANTIEMETIC AGENT; ANTIHISTAMINIC AGENT; ANTIHYPERTENSIVE AGENT; ATROPINE; BENZODIAZEPINE; CHOLINESTERASE INHIBITOR; DONEPEZIL; EMETIC AGENT; GALANTAMINE; INFUSION FLUID; LAXATIVE; OXYGEN; PRALIDOXIME; RIVASTIGMINE; TACRINE;

ADULT; AGED; ARTICLE; BRADYCARDIA; DEATH; DEMOGRAPHY; DIAPHORESIS; DIARRHEA; DIZZINESS; DROWSINESS; DRUG EXPOSURE; DRUG INTOXICATION; FEMALE; HOSPITAL ADMISSION; HUMAN; INTENSIVE CARE UNIT; LETHARGY; LONG TERM EXPOSURE; MAJOR CLINICAL STUDY; MALE; MEDICATION ERROR; NAUSEA; OUTCOMES RESEARCH; POISON CENTER; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SINGLE DRUG DOSE; TREMOR; UNITED STATES; UNSPECIFIED SIDE EFFECT; VERTIGO; VOMITING;

ADULT; AGED; AGED, 80 AND OVER; CHOLINESTERASE INHIBITORS; FEMALE; GALANTAMINE; GASTROINTESTINAL DISEASES; HUMANS; INDANS; MALE; MIDDLE AGED; PHENYLCARBAMATES; PIPERIDINES; POISON CONTROL CENTERS; RETROSPECTIVE STUDIES; TACRINE;

EID: 34748896508     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1K139     Document Type: Article

References (17)

1. Smith CP, Bores GM, Petko W, et al. Pharmacological activity and safety profile of P10358, a novel, orally active acetylcholinesterase inhibitor for Alzheimer's disease. J Pharmacol Exp Ther 1997;280:710-20.
2. Aguglia E, Onor ML, Saina M, Maso E. An open-label, comparative study of rivastigmine, donepezil and galantamine in a real-world setting. Curr Med Res Opin 2004;20:1747-52.
3. Blount PJ, Nguyen CD, McDeavitt JT. Clinical use of cholinomimetic agents: a review. J Head Trauma Rehabil 2002;17:314-21.
4. Gold Standard, Inc. Clinical pharmacology [tacrine]. http://Libproxy. uams.edu/Login?url=http://cpip.gsm.com (accessed 2005 Dec 28).
5. Package insert. Cognex (tacrine hydrochloride). Vega Baja, PR: Parke-Davis Pharmaceuticals, October 2000.
6. Sthal SM. The new Cholinesterase inhibitors for Alzheimer's disease, part 1: their similarities are different. J Clin Psychiatry 2000;61:710-1.
7. Gold Standard, Inc. Clinical pharmacology [donepezil]. http://Libproxy.uams.edu/Login?url=http://cpip.gsm.com (accessed 2005 Dec 28).
8. Package insert. Aricept (donepezil hydrochloride). New York, NY: Pfizer, March 2005.
9. Gold Standard, Inc. Clinical pharmacology [rivastigmine]. http://Libproxy.uams.edu/Login?url=http://cpip.gsm.com (accessed 2005 Dec 28).
10. Package insert. Exelon (rivastigmine tartrate). East Hanover, NJ: Novartis Pharmaceuticals, October 2004.
11. Gold Standard, Inc. Clinical pharmacology [galantamine]. http://Libproxy.uams.edu/Login?url=http://cpip.gsm.com (accessed 2005 Dec 28).
12. Package insert. Razadyne/Razadyne ER (galantamine hydrobromide/ galantamine hydrobromide ER). Titusville, NJ: Ortho-McNeil Neurologics, June 2005.
13. Lai MW, Klein-Schwartz W, Rogers GC. 2005 Annual report of the American Association of Poison Control Centers' national poisoning and exposure database. Clin Toxicol (Phila) 2006;44:803-932.
14. Greene YM, Novisasky J, Tariot PN. Donepezil overdose (letter). J Clin Psychiatry 1999;60:56-7.
15. Shepherd G, Klein-Schwartz W, Edwards R. Donepezil overdose: a ten-fold dosing error. Ann Pharmacother 1999;33:812-5. DOI 10.1345/aph.18273
16. Package insert. Protopam (pralidoxime chloride). Deerfield, IL: Baxter Healthcare, May 2004.
17. Carbamate insecticides (management/treatment protocol). POISONDEX System. Thomson Micromedex, Greenwood Village, CO (edition expired 6/2007).