Composite hemangioendothelioma: Report of 5 cases including one with associated Maffucci syndrome

American Journal of Surgical Pathology

Volumn 31, Issue 10, 2007, Pages 1567-1572

  Fukunaga, Masaharu ^a,e   Suzuki, Koyu ^b   Saegusa, Noriko ^c   Folpe, Andrew L ^d  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b ST LUKE'S INTERNATIONAL HOSPITAL   (Japan)

^c Department of Plastic Surgery ^*  (Japan)

^d MAYO CLINIC   (United States)

^e JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiomatosis; Composite hemangioendothelioma; Maffucci syndrome angiosarcoma

Indexed keywords

CD3 ANTIGEN; CD31 ANTIGEN;

ADULT; AGED; ARM TUMOR; ARTERIOVENOUS MALFORMATION; ARTICLE; BLOOD VESSEL; CANCER SURGERY; CAVERNOUS HEMANGIOMA; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONGENITAL TUMOR; DERMIS; DISEASE ASSOCIATION; ENCHONDROMA; ENDOTHELIUM CELL; FEMALE; FINGER AMPUTATION; FOLLOW UP; FOOT TUMOR; HEMANGIOENDOTHELIOMA; HEMANGIOMA; HISTORY OF MEDICINE; HUMAN; IMMUNOHISTOCHEMISTRY; KASABACH MERRITT SYNDROME; LYMPHANGIOMA; LYMPHOCYTIC INFILTRATION; MALE; MANDIBLE TUMOR; OSTEOCHONDROMA; OSTEOSCLEROSIS; PHYSICAL EXAMINATION; SKIN NODULE; SPINDLE CELL; SUBCUTANEOUS TISSUE; TUMOR; TUMOR RECURRENCE; VASCULAR LESION;

ADULT; AGED; ENCHONDROMATOSIS; FEMALE; HEMANGIOENDOTHELIOMA; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; NEOPLASM RECURRENCE, LOCAL; SOFT TISSUE NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 34748888381     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/PAS.0b013e318038f6b5     Document Type: Article

References (18)

1. Auyeung J, Mohanty K, Tayton K. Maffucci lymphangioma syndrome: an unusual variant of Ollier's disease, a case report and a review of the literature. J Pediatr Orothop B. 2003;12:147-150.
2. Biagioli M, Sbano P, Miracco C, et al. Composite cutaneous haemangioendothelioma: case report and review of the literature. Clin Exp Dermatol. 2005;30:385-387.
3. Fanburg JC, Meis-Kindblom JM, Rosenberg AE. Multiple enchondromas associated with spindle-cell hemangioendothelioma. An overlooked variant of Maffucci's syndrome. Am J Surg Pathol. 1995;19:1029-1038.
4. Fukunaga M, Ushigome S, Nikaido T, et al. Spindle cell hemangioendothelioma: an immunohistochemical and flow cytometric study of six cases. Pathol Int. 1995;45:589-595.
5. Fukunaga M, Endo Y, Masui F, et al. Retiform hemangioendothelioma. Virchows Arch. 1996;428:301-304.
6. Lewis RJ, Ketcham AS. Maffucci's syndrome: functional and neoplastic significance. Case report and review of literature. J Bone Joint (Am). 1973;55:1465-1479.
7. Mentzel T, Beham A, Calonje E, et al. Epithelioid hemangioendothelioma of the skin and soft tissues; clinicopathologic and immunohistochemical studies of 30 cases. Am J Surg Pathol. 1997;21:363-374.
8. Nayler SJ, Rubin BP, Calonje E, et al. Composite hemangioendothelioma: a complex low-grade vascular lesion mimicking angiosarcoma. Am J Surg Pathol. 2000;24:352-356.
9. Perkins P, Weiss SW. Spindle cell hemangioendothelioma. An analysis of 78 cases with reassessment of its pathogenesis and biologic behavior. Am J Surg Pathol. 1996;20:1196-1204.
10. Rao VK, Weiss SW. Angiomatosis of soft tissue. An analysis of the histologic features and clinical outcome in 51 cases. Am J Surg Pathol. 1992;16:764-771.
11. Reis-Filho JS, Paiva ME, Lopes JM. Congenital composite hemangioendothelioma: case report and reappraisal of the hemangioendothelioma spectrum. J Cutan Pathol. 2002;29:226-231.
12. Rubin BP. Composite haemangioendothelioma. In: Fletcher CDM, Unni KK, Mertens F, eds. Tumours of Soft Tissue and Bone. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IRAC Press; 2002:168-169.
13. Rubin BP, Nayler SJ, Calonje E, et al. Composite hemangioendothelioma: a complex vascular lesion mimicking angiosarcoma. Lab Invest. 1998;64:14A.
14. Silva EG, Phillips MJ, Langer B, et al. Spindle and histiocytoid (epithelioid) hemangioendothelioma. Primary in lymph node. Am J Clin Pathol. 1986;85:731-735.
15. Weiss SW. Angiomatosis. In: Fletcher CDM, Unni KK, Mertens F, eds. Tumours of Soft Tissue and Bone. World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: IRAC Press; 2002:161.
16. Weiss S, Enzinger FM. Epithelioid hemangioendothelioma: a vascular tumor often mistaken for a carcinoma. Cancer. 1982;50:970-981.
17. Yanez S, Val-Bernal JF, Mira C, et al. Spindle cell hemangioendothelioma associated with multiple skeletal enchondromatosis: a variant of Maffucci's syndrome. Gen Diagn Pathol. 1998;143:331-335.
18. Zoltie N, Roberts PF. Spindle cell hemangioendothelioma in association with epithelioid hemangioendothelioma. Histopathology. 1989;15:544-546.