Significance and mechanism of microsatellite instability in laryngeal squamous cell carcinoma

Journal of Otolaryngology

Volumn 36, Issue 3, 2007, Pages 168-174

  Zhigang, Huang ^a   Demin, Han ^a   Han, Gao ^a   Erzhong, Fan ^a   Xiaohong, Chen ^a   Hongbo, Xu ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

hMLH1; hMSH2; Laryngeal squamous cell carcinoma; Microsatellite instability; Mismatch repair gene

Indexed keywords

SINGLE STRANDED DNA;

ADULT; AGED; ARTICLE; CANCER RECURRENCE; CANCER RELAPSE; CARCINOGENESIS; CHROMOSOME 17P; CHROMOSOME 1P; CHROMOSOME 3P; CHROMOSOME 5Q; CHROMOSOME 9P; CLINICAL ARTICLE; DISEASE SEVERITY; DNA POLYMORPHISM; FEMALE; GENDER; GENE EXPRESSION; GENE FREQUENCY; GROUPS BY AGE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LARYNX CARCINOMA; MALE; MARKER GENE; MICRODISSECTION; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MOLECULAR DYNAMICS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SILVER STAINING; SMOKING; SQUAMOUS CELL CARCINOMA; STATISTICAL SIGNIFICANCE; TUMOR DIFFERENTIATION; TUMOR LOCALIZATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CELL DIFFERENTIATION; DNA MISMATCH REPAIR; EPITHELIUM; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LARYNGEAL NEOPLASMS; MALE; MICRODISSECTION; MICROSATELLITE INSTABILITY; MIDDLE AGED; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TUMOR MARKERS, BIOLOGICAL;

EID: 34748877623     PISSN: 03816605     EISSN: None     Source Type: Journal    
DOI: 10.2310/7070.2007.0015     Document Type: Article

References (18)

1. Garfinkel DJ, Bailis AM. Nucleotide excision repair, genome stability, and human disease: new insight from model systems. J Biomed Biotechnol 2002;2:55-60.
2. Wang Y, Irish J, MacMillan C, et al. High frequency of microsatellite instability in young patients with head-and-neck squamous-cell carcinoma: lack of involvement of the mismatch repair genes hMLH1 and hMSH2. Int J Cancer 2001;93:353-60.
3. Liu K, Zuo C, Luo QK, et al. Promoter hypermethylation and inactivation of hMLH1, a DNA mismatch repair gene, in head and neck squamous cell carcinoma. Diagn Mol Pathol 2003;12:50-6.
4. Pedroni M, Sala E, Scarselli A, et al. Microsatellite instability and mismatch-repair protein expression in hereditary and sporadic colorectal carcinogenesis. Cancer Res 2001;61:896-9.
5. Ma AH, Xia L, Littman SJ, et al. Somatic mutation of hPMS2 as a possible cause of sporadic human colon cancer with microsatellite instability. Oncogene 2000;19:2249-56.
6. Planck M, Rambech E, Moslein G, et al. High frequency of microsatellite instability and loss of mismatch-repair protein expression in patients with double primary tumors of the endometrium and colorectum. Cancer 2002;94:2502-10.
7. Boland CR, Thibodeau SN, Hamilton SR, et al. A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;58:5248-57.
8. de Jong AE, van Puijenbroek M, Hendriks Y, et al. Microsatellite instability, immunohistochemistry, and additional pms2 staining in suspected hereditary nonpolyposis colorectal cancer. Clin Cancer Res 2004;10:972-80.
9. Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993;260:816-9.
10. Waterston AM, Cassidy J. Adjuvant treatment strategies for early colon cancer. Drugs 2005;65:1935-47.
11. Zhang SH, Cong WM, Xian ZH, et al. Clinicopathological significance of loss of heterozygosity and microsatellite instability in hepatocellular carcinoma in China. World J Gastroenterol 2005; 11:3034-9.
12. Worthley DL, Walsh MD, Barker M, et al. Familial mutations in pms2 can cause autosomal dominant hereditary nonpolyposis colorectal cancer. Gastroenterology 2005;128:1431-6.
13. Wang B, Chen Y, Wen S, et al. [Investigation on recurrent-associated gene expression pattern of recurrent-laryngeal squamous cell carcinoma]. Lin Chuang Er Bi Yan Hou Ke Za Zhi 2003; 17:339-41.
14. Kubo N, Yashiro M, Ohira M, et al. Frequent microsatellite instability in primary esophageal carcinoma associated with extraesophageal primary carcinoma. Int J Cancer 2005;114:166-73.
15. Glavac D, Volavsek M, Potocnik U, et al. Low microsatellite instability and high loss of heterozygosity rates indicate dominant role of the suppressor pathway in squamous cell carcinoma of head and neck and loss of heterozygosity of 11q14.3 correlates with tumor grade. Cancer Genet Cytogenet 2003;146:27-32.
16. Ng IO, Xiao L, Lam KY, et al. Microsatellite alterations in squamous cell carcinoma of the head and neck - clustering of loss of heterozygosity in a distinct subset. Oral Oncol 2000;36:484-90.
17. Smigiel R, Stembalska-Kozlowska A, Mirghomizadeh F, et al. Correlation among loss of heterozygosity, promoter methylation and protein expression of MLH1 in larynx cancer. Oncol Rep 2004; 11:707-10.
18. Mao L, Lee DJ, Tockman MS, et al. Microsatellite alterations as clonal markers for the detection of human cancer. Proc Natl Acad Sci U S A 1994;91:9871-5.